Publications de Sylvain Jean-François Harquel

Brain Oscillatory Modes as a Proxy of Stroke Recovery

Dimitri Nestor Alice Van De Ville, Olaf Blanke, Philip Egger, Sylvain Jean-François Harquel, Silvestro Micera, Nathalie Heidi Meyer, Elena Beanato, Julia Brügger, Friedhelm Christoph Hummel, Takuya Morishita, Maximilian Jonas Wessel, Philipp Johannes Koch, Giorgia Giulia Evangelista, Andéol Geoffroy Cadic-Melchior, Pauline Menoud, Lisa Aïcha Mireille Julie Fleury

Background Stroke is the leading cause of long-term disability, making the search for successful rehabilitation treatment one of the most important public health issues. A better understanding of the neural mechanisms underlying impairment and recovery is ...

SAGE Publications2025

Reduced spatial frequency differentiation and sex‐related specificities in fearful face detection in autism: Insights from EEG and the predictive brain model

Sylvain Jean-François Harquel

Face processing relies on predictive processes driven by low spatial frequencies (LSF) that convey coarse information prior to fine information conveyed by high spatial frequencies. However, autistic individuals might have atypical predictive processes, co ...

Wiley2024

MEP and TEP features variability: is it just the brain-state?

Sylvain Jean-François Harquel, Michele Bevilacqua, Claudia Bigoni, Friedhelm Christoph Hummel, Estelle Emeline Raffin, Andéol Geoffroy Cadic-Melchior

Objective. The literature investigating the effects of alpha oscillations on corticospinal excitability is divergent. We believe inconsistency in the findings may arise, among others, from the electroencephalography (EEG) processing for brain-state determi ...

Iop Publishing Ltd2024

Sex modulation of faces prediction error in the autistic brain

Sylvain Jean-François Harquel

Recent research suggests that autistic females may have superior socio-cognitive abilities compared to autistic males, potentially contributing to underdiagnosis in females. However, it remains unclear whether these differences arise from distinct neurophy ...

Nature Portfolio2024

Physiology-inspired bifocal fronto-parietal tACS for working memory enhancement

Sylvain Jean-François Harquel, Pablo Maceira Elvira, Friedhelm Christoph Hummel, Traian Popa

Aging populations face significant cognitive challenges, particularly in working memory (WM). Transcranial alternating current stimulation (tACS) offer promising avenues for cognitive enhancement, especially when inspired by brain physiology. This study (N ...

2024

Stroke Recovery–Related Changes in Cortical Reactivity Based on Modulation of Intracortical Inhibition

Dimitri Nestor Alice Van De Ville, Olaf Blanke, Philip Egger, Sylvain Jean-François Harquel, Silvestro Micera, Elena Beanato, Takuya Morishita, Giorgia Giulia Evangelista, Pauline Menoud, Lisa Aïcha Mireille Julie Fleury

BACKGROUND: Cortical excitation/inhibition dynamics have been suggested as a key mechanism occurring after stroke. Their supportive or maladaptive role in the course of recovery is still not completely understood. Here, we used transcranial m ...

Ovid Technologies (Wolters Kluwer Health)2024

Modulation of Visually Induced Self-motion Illusions by α Transcranial Electric Stimulation over the Superior Parietal Cortex

Sylvain Jean-François Harquel

The growing popularity of virtual reality systems has led to a renewed interest in understanding the neurophysiological correlates of the illusion of self-motion (vection), a phenomenon that can be both intentionally induced or avoided in such systems, dep ...

Mit Press2024

Novel personalized treatment strategy for patients with chronic stroke with severe upper-extremity impairment: The first patient of the AVANCER trial

Sylvain Jean-François Harquel, Andrea Crema, Elena Beanato, Claudia Bigoni, Friedhelm Christoph Hummel, Takuya Morishita, Maximilian Jonas Wessel, Giorgia Giulia Evangelista, Sarah Bernardina Zandvliet

Background: Around 25% of patients who have had a stroke suffer from severe upper-limb impairment and lack effective rehabilitation strategies. The AVANCER proof-of-concept clinical trial (NCT04448483) tackles this issue through an intensive and personaliz ...

CELL PRESS2023

Motor imagery training to improve language processing: What are the arguments?

Sylvain Jean-François Harquel

Studies showed that motor expertise was found to induce improvement in language processing. Grounded and situated approaches attributed this effect to an underlying automatic simulation of the motor experience elicited by action words, similar to motor ima ...

FRONTIERS MEDIA SA2023

Multi-scale and cross-dimensional TMS mapping: A proof of principle in patients with Parkinson's disease and deep brain stimulation

Sylvain Jean-François Harquel, Estelle Emeline Raffin

IntroductionTranscranial magnetic stimulation (TMS) mapping has become a critical tool for exploratory studies of the human corticomotor (M1) organization. Here, we propose to gather existing cutting-edge TMS-EMG and TMS-EEG approaches into a combined mult ...

FRONTIERS MEDIA SA2023

Toward individualized medicine in stroke-The TiMeS project: Protocol of longitudinal, multi-modal, multi-domain study in stroke

Jean-Philippe Thiran, Dimitri Nestor Alice Van De Ville, Olaf Blanke, Philip Egger, Sylvain Jean-François Harquel, Silvestro Micera, Nathalie Heidi Meyer, Elena Beanato, Valérie Rita Madeleine Zufferey, Gabriel Girard, Julia Brügger, Friedhelm Christoph Hummel, Takuya Morishita, Maximilian Jonas Wessel, Philipp Johannes Koch, Estelle Emeline Raffin, Andéol Geoffroy Cadic-Melchior, Traian Popa, Pauline Menoud, Lisa Aïcha Mireille Julie Fleury

Despite recent improvements, complete motor recovery occurs in < 15% of stroke patients. To improve the therapeutic outcomes, there is a strong need to tailor treatments to each individual patient. However, there is a lack of knowledge concerning the preci ...

FRONTIERS MEDIA SA2022

The Predictive Role of Low Spatial Frequencies in Automatic Face Processing: A Visual Mismatch Negativity Investigation

Sylvain Jean-François Harquel

Visual processing is thought to function in a coarse-to-fine manner. Low spatial frequencies (LSF), conveying coarse information, would be processed early to generate predictions. These LSF-based predictions would facilitate the further integration of high ...

FRONTIERS MEDIA SA2022

Kinesthetic motor-imagery training improves performance on lexical-semantic access

Sylvain Jean-François Harquel, Camille Bonnet

The objective of this study was to evaluate the effect of Motor Imagery (MI) training on language comprehension. In line with literature suggesting an intimate relationship between the language and the motor system, we proposed that a MI-training could imp ...

PUBLIC LIBRARY SCIENCE2022

Exploring the spatial resolution of TMS-EEG coupling on the sensorimotor region

Sylvain Jean-François Harquel, Estelle Emeline Raffin

The use of TMS-EEG coupling as a neuroimaging tool for the functional exploration of the human brain recently gained strong interest. If this tool directly inherits the fine temporal resolution from EEG, its spatial counterpart remains unknown. In this stu ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2022