Publications de Mélanie Abonnenc

Electrochemical reactions and ionization processes

Hubert Girault, Michel Prudent, Niels Erik Lion, Mélanie Abonnenc, Hongyan Bi, Liang Qiao

Electrochemical or photo-electrochemical reactions in both electrospray ionization and laser desorption ionization are discussed stressing the role of the electrode reaction in influencing the ionization process. In particular, upon application of a high v ...

2010

Electrochemical Aspects of Electrospray and Laser Desorption/Ionization for Mass Spectrometry

Hubert Girault, Mélanie Abonnenc, Liang Qiao

Soft-ionization methods, namely electrospray ionization and laser desorption/ionization, are widely used to transfer large molecules as intact gas-phase ions either from a solution or from a solid substrate. During both processes, in-source electrochemical ...

2010

Miniaturized analytical systems for mass spectrometry-based protein studies

Mélanie Abonnenc

Current proteomic strategies depend strongly on the development of analytical methodologies and instrumentation. In parallel to the development of mass spectrometry (MS) - based proteomic workflows, microfluidic devices emerged in this field as a flexible ...

EPFL2009

Magnetic track array for efficient bead capture in microchannels

Hubert Girault, Anne-Laure Gassner, Mélanie Abonnenc

Magnetism-based microsystems, as those dedicated to immunoaffinity separations or (bio)chemical reactions, take benefit of the large surface area-to-volume ratio provided by the immobilized magnetic beads, thus increasing the sensitivity of the analysis. A ...

Springer Verlag2009

Sandwich mixer–reactor: influence of the diffusion coefficient and flow rate ratios

Hubert Girault, Mélanie Abonnenc

A sandwich mixer consists of mixing two solutions in a channel, one central laminar flow being sandwiched between two outer flow solutions. The present numerical study considers the convection– diffusion of two reacting species A and B, provided respective ...

2009

Magnetic forces produced by rectangular permanent magnets in static microsystems

Hubert Girault, Joël Stéphane Rossier, Anne-Laure Gassner, Mélanie Abonnenc, Hong-Xu Chen

Finite element numerical simulations were carried out in 2D geometries to map the magnetic field and force distribution produced by rectangular permanent magnets as a function of their size and position with respect to a microchannel. A single magnet, two ...

2009

Electrospray Micromixer Chip for On-Line Derivatization and Kinetic Studies

Hubert Girault, Niels Erik Lion, Loïc Dayon, Brice Perruche, Mélanie Abonnenc

An electrospray microchip for mass spectrometry comprising an integrated passive mixer to carry out on-chip chemical derivatizations is described. The microchip fabricated using UV-photoablation is composed of two microchannels linked together by a liquid ...

2008

Multitrack electrospray chips

Hubert Girault, Michel Prudent, Niels Erik Lion, Loïc Dayon, Mélanie Abonnenc

Multitrack electrospray chips (MTEC) were fabricated by UV-photoablation of polyethylene terephthalate (PET) substrates. They are composed of an array of up to six microchannels that are successively used as electrospray ionization (ESI) emitters for mass ...

Wiley-Blackwell2006