Davide Demurtas

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Publications associées (32)

Spatial SPION Localization in Liposome Membranes

Alke Fink, Davide Demurtas

Nanocarriers, including liposomes, offer great opportunities for targeted and controlled therapy. The development in this field has led to a large panel of drug delivery systems, which can be classified into 3 different nanovector generations. However, the ...

Institute of Electrical and Electronics Engineers2013

Low-Temperature Preparation of Tailored Carbon Nanostructures in Water

Raffaele Mezzenga, Vincent Laporte, Davide Demurtas, Anna Fontcuberta i Morral, Bernt Ketterer, Holger Frauenrath, Tobias Hoheisel, Ruth Szilluweit, Martin Fritzsche

The development of low-temperature carbonization procedures promises to provide novel nanostructured carbon materials that are of high current interest in materials science and technology. Here, we report a "wet-chemical" carbonization method that utilizes ...

American Chemical Society2012

Structural modifications of ionic liquid surfactants for improving the water dispersibility of carbon nanotubes: an experimental and theoretical study

Davide Demurtas

The 1-hexadecyl-3-vinylimidazolium bromide (hvimBr), a water-soluble long-chain imidazolium ionic liquid (IL) with surfactant properties, showed the ability to produce stable homogeneous aqueous dispersions of pristine Single-Walled Carbon Nanotubes (SWNTs ...

2011

Cooperative kinking at distant sites in mechanically stressed DNA

Andrzej Stasiak, Guillaume Witz, Julien Dorier, Davide Demurtas

In cells, DNA is routinely subjected to significant levels of bending and twisting. In some cases, such as under physiological levels of supercoiling, DNA can be so highly strained, that it transitions into non-canonical structural conformations that are c ...

Oxford University Press2011

Assessing the Role of Poly(ethylehe glycol-bl-propylene sulfide) (PEG-PPS) Block Copolymers in the Preparation of Carbon Nanotube Biocompatible Dispersions

Jeffrey Alan Hubbell, Conlin O'Neil, Davide Demurtas

Amphiphilic block copolymers based on hydrophobic polysulfides (poly(propylene sulfide), PPS) and hydrophilic polyethers (poly(ethylene glycol), PEG) have been used to solubilize and disperse single-walled carbon nanotubes (SWNTs). The obtained highly conc ...

American Chemical Society2010

A Novel Method for the Encapsulation of Biomolecules into Polymersomes via Direct Hydration

Jeffrey Alan Hubbell, Conlin O'Neil, Andrija Finka, Davide Demurtas

One of the major engineering challenges for the implementation of block copolymer vesicles, or polymersomes, as therapeutic drug carriers is obtaining high encapsulation efficiencies for biomolecules. Here we present it novel method for encapsulation of pr ...

2009

Extracellular matrix binding mixed micelles for drug delivery applications

Jutta Christine Wandrey, Jeffrey Alan Hubbell, Davide Demurtas

Received 5 January 2009 Accepted 22 March 2009 Available online 27 March 2009 Keywords: Mixed micelles Drug delivery Block copolymers Sirolimus Extracellular matrix We present the formation of collagen-binding mixed micelles and their potential suitability ...

2009

Micelles for delivery of nitric oxide

Nikolaos Stergiopoulos, Jeffrey Alan Hubbell, Simone Cavadini, Yun Suk Jo, Jay Gantz, Tyler Nerton Thacher, Davide Demurtas

We designed block copolymer pro-amphiphiles and amphiphiles for providing very long-term release of nitric oxide (NO). A block copolymer of N-acryloylmorpholine (AM, as a hydrophile) and N-acryloyl-2,5-dimethylpiperazine (AZd, as a hydrophilic precursor) w ...

2009

Bending modes of DNA directly addressed by cryo-electron microscopy of DNA minicircles

John Maddocks, Jacques Dubochet, Andrzej Stasiak, Arnaud Amzallag, Davide Demurtas

We use cryo-electron microscopy (cryo-EM) to study the 3D shapes of 94-bp-long DNA minicircles and address the question of whether cyclization of such short DNA molecules necessitates the formation of sharp, localized kinks in DNA or whether the necessary ...

Oxford University Press2009

RAFT homo- and copolymerization of N-acryloyl-morpholine, piperidine, and azocane and their self-assembled structures

Jeffrey Alan Hubbell, Yun Suk Jo, Jay Gantz, Davide Demurtas

We present new polymeric amphiphiles derived from N-acryloyl derivatives of the cyclic secondary amines: morpholine, piperidine, and azocane polymerized by reversible addition -fragmentation transfer (RAFT) polymerization. Both homopolymerization and block ...

American Chemical Society2008

PEG-b-PPS diblock copolymer aggregates for hydrophobic drug solubilization and release: Cyclosporin A as an example

Jeffrey Alan Hubbell, Davide Demurtas

Micelles formed from amphiphilic block copolymers have been explored in recent years as carriers for hydrophobic drugs. In an aqueous environment, the hydrophobic blocks form the core of the micelle, which can host lipophilic drugs, while the hydrophilic b ...

2008

Multifunctional Lipid/Quantum-Dots Hybrid Nanocontainers for Controlled Targeting of Live Cells

Pierre-Yves Bolinger, Horst Vogel, Jacques Dubochet, Gopakumar Gopalakrishnan, Paulina Izewska, Christophe Danelon, Davide Demurtas

In this communication, we report on an interesting observation of wide-ranging potential for cellular imaging and manipulation: Hydrophobic QDs can be easily incorporated into the bilayer membrane of lipid vesicles. Such lipid/QD nanocontainer hybrid vesic ...

Wiley-VCH Verlag GmbH2006

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