Publications de Konstantin Zhurov

Homo- and Heterodinuclear Iron Clathrochelate Complexes with Functional Groups in the Ligand Periphery

Andrzej Sienkiewicz, Kay Severin, Rosario Scopelliti, Henrik Moodysson Rønnow, Ivica Zivkovic, Mathieu Jérémie Marmier, Konstantin Zhurov, Cornel Fink, José Luis Bila

2018

The Ligand Aspect Ratio as a Decisive Factor for the Self-Assembly of Coordination Cages

Kay Severin, Rosario Scopelliti, Euro Solari, Philip Pattison, Konstantin Zhurov, Matthew David Wise, Alba Finelli, Giacomo Cecot, Suzanne Maria Jansze

It is possible to control the geometry and the composition of metallasupramolecular assemblies via the aspect ratio of their ligands. This point is demonstrated for a series of iron- and palladium-based coordination cages. Functionalized clathrochelate com ...

2016

Molecularly Defined Nanostructures Based on a Novel AAA-DDD Triple Hydrogen Bonding Motif

Kay Severin, Konstantin Zhurov, Clément Alexis Vuilleumier, Marcus Papmeyer

A facile and flexible method for the synthesis of a new AAA–DDD triple hydrogen-bonding motif is described. Polytopic supramolecular building blocks with precisely oriented AAA and DDD groups are thus accessible in few steps. These building blocks were use ...

Wiley-VCH Verlag GmbH2016

Producing absorption mode Fourier transform ion cyclotron resonance mass spectra with non-quadratic phase correction functions

Yury Tsybin, Konstantin Zhurov, Anton Kozhinov, Konstantin Nagornov

RATIONALE: Previously described methods for producing absorption mode Fourier transform ion cyclotron resonance (FTICR) mass spectra have all relied on the phase correction function being quadratic. This assumption has been found to be invalid for some ins ...

Wiley-Blackwell2015

A Functional Group Approach for Prediction of APPI Response of Organic Synthetic Targets

Yury Tsybin, Konstantin Zhurov, Laure Menin, Thomas Clément Di Franco

Atmospheric pressure photoionization (APPI) is a technique of choice for ionization of non-polar molecules in mass spectrometry (MS). Reported APPI-based studies tend to focus on a selected compound class, which may contain a variety of functional groups. ...

Springer2015

On the use of electron capture rate constants to describe electron capture dissociation mass spectrometry of peptides

Yury Tsybin, Konstantin Zhurov, Aleksey Vorobyev, Unige Anna Laskay

Electron capture dissociation (ECD) tandem mass spectrometry (MS/MS) is a powerful analytical tool for peptide and protein structure analysis. The product ion abundance (PIA) distribution in ECD MS/MS is known to vary as a function of electron irradiation ...

Im Publications2015

Distinguishing analyte from noise components in mass spectra of complex samples: where to cut the noise?

Yury Tsybin, Konstantin Zhurov, Luca Fornelli, Anton Kozhinov

Fourier transform mass spectrometry (FTMS) enables comprehensive analysis of complex molecular mixtures. Given the broad intensity ranges of components in the mass spectra, it is imperative to accurately determine a noise threshold level above which peak a ...

Amer Chemical Soc2014

Ping-Pong Protons: How Hydrogen Bonding Networks Facilitate Heterolytic Bond Cleavages in Peptide Radical Cations

Yury Tsybin, Anne-Clémence Corminboeuf, Konstantin Zhurov, Matthew Wodrich

Electron capture and electron transfer dissociation (ECD/ETD) tandem mass spectrometry (MS/MS) are commonly employed techniques for biomolecular analysis. The ECD/ETD process predominately cleaves N-C-alpha peptide backbone bonds, leading to primary sequen ...

Amer Chemical Soc2014

On the Viability of Heterolytic Peptide N-Calpha Bond Cleavage in Electron Capture and Transfer Dissociation Mass Spectrometry

Yury Tsybin, Anne-Clémence Corminboeuf, Konstantin Zhurov, Matthew Wodrich

While frequently employed as an experimental technique, the mechanistic picture surrounding the gas-phase dissociation of peptides carrying multiple positive charges during electron capture and electron transfer dissociation tandem mass spectrometry remain ...

Amer Chemical Soc2014

Self-Assembly of a Giant Molecular Solomon Link from 30 Subcomponents

Kay Severin, Rosario Scopelliti, Clément Schouwey, Yury Tsybin, Konstantin Zhurov, Konstantin Nagornov

The synthesis of topologically complex structures, such as links and knots, is one of the current challenges in supramolecular chemistry. The so-called Solomon link consists of two doubly interlocked rings. Despite being a rather simple link from a topolog ...

Wiley-Blackwell2014

Advances in Structural Elucidation of Small Molecules via High Performance Mass Spectrometry

Konstantin Zhurov

Qualitative and quantitative analyte analysis is omnipresent: from quality control in food, pharmaceutical, biotechnology industries, to new molecular syntheses, detection of explosives and drugs, as well as natural compound mixture analysis, such as crude ...

EPFL2014

Evaluation of high-field Orbitrap Fourier transform mass spectrometer for petroleomics

Yury Tsybin, Konstantin Zhurov, Anton Kozhinov

The performance of the high-field Orbitrap Fourier transform mass spectrometer (FTMS) is evaluated in the context of petroleum sample analysis. Pertinent characteristics including resolving power, mass accuracy, and spectral dynamic range are tested with r ...

Amer Chemical Soc2013

Iterative Method for Mass Spectra Recalibration via Empirical Estimation of the Mass Calibration Function for Fourier Transform Mass Spectrometry-Based Petroleomics

Yury Tsybin, Konstantin Zhurov, Anton Kozhinov

We describe a mass spectra recalibration method, which enables analysis of petroleum samples with Orbitrap FTMS. In this method, the mass calibration function is estimated on the basis of mass-to-charge ratios and abundances of internal calibrants without ...

Amer Chemical Soc2013

Hexagonal Class Representation for Fingerprinting and Facile Comparison of Petroleomic Samples

Yury Tsybin, Konstantin Zhurov, Anton Kozhinov

Because of the high complexity of petroleomic-type samples, there is a need for efficient ways of visualizing and interpreting the resulting data in mass spectrometry-based petroleomics. Over the years, several graphing approaches have become widespread, y ...

Amer Chemical Soc2013

Principles of electron capture and transfer dissociation mass spectrometry applied to peptide and protein structure analysis

Yury Tsybin, Konstantin Zhurov, Matthew Wodrich, Luca Fornelli, Unige Anna Laskay

This tutorial review describes the principles and practices of electron capture and transfer dissociation (ECD/ETD or ExD) mass spectrometry (MS) employed for peptide and protein structure analysis. ExD MS relies on interactions between gas phase peptide o ...

Royal Society of Chemistry2013

Heterolytic N-Calpha Bond Cleavage in Electron Capture and Transfer Dissociation of Peptide Cations

Hisham Ben Hamidane, Yury Tsybin, Anne-Clémence Corminboeuf, Konstantin Zhurov, Matthew Wodrich, Aleksey Vorobyev

Mass spectrometry techniques employing electron capture and electron transfer dissociation represent powerful approaches for the analysis of biological samples. Despite routine employment in analytical fields, the underlying physical processes dictating pe ...

Amer Chemical Soc2012

Borophosphonate Cages: Easily Accessible and Constitutionally Dynamic Heterocubane Scaffolds

Kay Severin, Rosario Scopelliti, Konstantin Zhurov, Laure Menin, Justus Tönnemann

A versatile and experimentally facile procedure for the synthesis of borophosphonate cages of the general formula [tBuPO3BR′]4 is described. The method involves heating of tert-butylphosphonic acid with a boronic acid in toluene to give borophosphonates in ...

Wiley-V C H Verlag Gmbh2012