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Sandro Carrara

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Publications associées (297)

Enhancing Prostate Cancer Diagnosis with In-Memory Sensing and Edge Computing of Percent-free PSA Index

Sandro Carrara, Gian Luca Barbruni, Ata Jedari Golparvar

In this paper, we are presenting a new architecture to directly compute the ‘Percent-free PSA’ diagnostics index to enhance the differentiation of prostate cancer from benign prostatic disease. The proposed circuit uses silicon nanowires-based memristive b ...

Institute of Electrical and Electronics Engineers Inc.2024

Organic Memristive Devices with Capacitive-Coupled Effect: A Novel Approach for Histamine Sensing

Sandro Carrara

In this work, we developed simple polymer-based memristive devices specifically designed for biosensing applications. The devices consist of two gold electrodes connected by a biocompatible polymeric resistive layer made of poly(3,4 ethyldioxythiophene)pol ...

Institute of Electrical and Electronics Engineers Inc.2024

Emulating Multimemristive Behavior of Silicon Nanowire-Based Biosensors by Using CMOS-Based Implementations

Sandro Carrara, Junrui Chen, Kapil Bhardwaj

The research presented in this article draws inspiration from previous efforts aimed at replicating the functions of various solid-state memristors using a variety of materials. The memristor circuit emulator serves as a cost-effective tool for circuit des ...

Ieee-Inst Electrical Electronics Engineers Inc2024

Liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) methods for the therapeutic drug monitoring of cytotoxic anticancer drugs: An update

Sandro Carrara

In the era of precision medicine, there is increasing evidence that conventional cytotoxic agents may be suitable candidates for therapeutic drug monitoring (TDM)- guided drug dosage adjustments and patient's tailored personalization of non-selective chemo ...

Elsevier2024

A Frequency-Switching Inductive Power Transfer System for Wireless, Miniaturised and Large-Scale Neural Interfaces

Sandro Carrara, Diego Ghezzi, Gian Luca Barbruni

Three-coil inductive power transfer is the state-of-the-art solution to power multiple miniaturised neural implants. However, the maximum delivered power is limited by the efficiency of the powering link and safety constrains. Here we propose a frequency-s ...

Ieee-Inst Electrical Electronics Engineers Inc2024

Identification and Quantification of Multiple Drugs by Machine Learning on Electrochemical Sensors for Therapeutic Drug Monitoring

Sandro Carrara

Electrochemical sensors play a pivotal role in advancing therapeutic drug monitoring (TDM) and personalized therapy. However, the insufficient selectivity of electrochemical sensors based on cytochromes P450 poses a great need for innovative machine learni ...

2024

In-Memory Sensing and Computing for Cancer Diagnostics: A Perspective Paper

Sandro Carrara, Gian Luca Barbruni, Ata Jedari Golparvar, Junrui Chen

During the past two decades, a number of two-terminal switching devices have been demonstrated in the literature. They typically exhibit hysteric behavior in the current-to-voltage characteristics. These devices have often been also referred to as memristi ...

Ieee-Inst Electrical Electronics Engineers Inc2024

Multichannel Radiation-Compensated Systems for Temperature and Humidity Monitoring for High Energy Physics Detectors

Sandro Carrara, Amar Kapic

Monitoring humidity and temperature in silicon-based high-energy physics (HEP) detectors is indispensable but challenging due to space restrictions, radiation, sub-zero temperatures, and strong magnetic fields. This manuscript presents humidity and tempera ...

2024

A 69 µm2 Sub-nW/kHz Capacitor-less Ring Oscillator for Ultra-Miniaturized Implants

Sandro Carrara, Gian Luca Barbruni, Ali Meimandi

This paper presents an ultra-miniaturized, ultra-low-power, capacitor-less CMOS ring oscillator based on dynamic leakage suppression technique. Measurement results demonstrated an oscillation frequency of 21.89 kHz and a power consumption of 7.9 nW for a s ...

Institute of Electrical and Electronics Engineers Inc.2024

A Novel Microfluidic System for Capacitive Detection Via Magnetophoretic Separation of Malaria-Infected Red Blood Cells

Sandro Carrara, Ali Meimandi

Malaria continues to pose a significant global health challenge, with substantial impediments arising from the need for more reliable, effective, and economically viable diagnostic tools, particularly for early detection. This research introduces a novel m ...

2024

A Wearable Real-Time System for Simultaneous Wireless Power and Data Transmission to Cortical Visual Prosthesis

Sandro Carrara, Gian Luca Barbruni

Wireless, miniaturised and distributed neural interfaces are emerging neurotechnologies. Although extensive research efforts contribute to their technological advancement, the need for real-time systems enabling simultaneous wireless information and power ...

Ieee-Inst Electrical Electronics Engineers Inc2024

Importance of Sex-Dependent Differences for Dosing Selection and Optimization of Chemotherapeutic Drugs

Sandro Carrara

Background: Despite major advances in cancer treatment in the past years, there is a need to optimize chemotherapeutic drug dosing strategies to reduce toxicities, suboptimal responses, and the risk of relapse. Most cancer drugs have a narrow therapeutic i ...

KARGER2024

Unveiling the effect of Bi in ZnFe2O4 nanoparticles in electrochemical sensors

Sandro Carrara

This work investigates the effect of the inclusion of Bi3+ ions in ZnFe2O4 nanoparticles on electron transfer at the electrochemical interface. ZnBixFe2-xO4 (x = 0, 0.5, 1, 2) nanomaterials are synthesized and the impact of Bi3+ ions on the chemical featur ...

2024

Electrochemical sensors modified with iron oxide nanoparticles/ nanocomposites for voltammetric detection of Pb (II) in water: A review

Sandro Carrara

Permissible limits of Pb 2+ in drinking water are being reduced from 10 mu gL -1 to 5 mu gL -1 , which calls for rapid, and highly reliable detection techniques. Electrochemical sensors have garnered attention in detection of heavy metal ions in environmen ...

Cell Press2024

Development of an Integrated CMUTs-Based Resonant Biosensor for Label-Free Detection of DNA with Improved Selectivity by Ethylene- Glycol Alkanethiols

Sandro Carrara, Gian Luca Barbruni, Yihe Zhao

Gravimetric resonant-inspired biosensors have attracted increasing attention in industrial and point-of- care applications, enabling label-free detection of biomarkers such as DNA and antibodies. Capacitive micromachined ultrasonic transducers (CMUTs) are ...

ELSEVIER2024

Polymer-Based Memristive Devices for Ammonium Biosensing

Sandro Carrara

Memristive devices offer a promising approach for biosensing due to their high sensitivity. In two-terminal planar devices, the movement of charged species in the semiconductor channel creates a voltage gap, which can be exploited for sensing. In this stud ...

IEEE2024

Exploring Memristive Biosensing Dynamics: A COMSOL Multiphysics Approach

Sandro Carrara

This paper presents a novel methodology for mod-eling memristive biosensing within COMSOL Multiphysics, fo-cusing on critical performance metrics such as antigen-antibody binding concentration and output resistive states. By studying the impact of increasi ...

Institute of Electrical and Electronics Engineers Inc.2024

High-Efficiency Reconfigurable CMOS RF-to-DC Converter System for Ultra-Low-Power Wireless Sensor Nodes with Efficient MPPT Circuitry

Catherine Dehollain, Sandro Carrara, Roberto La Rosa

This paper presents a novel CMOS RF-to-DC converter for ultra-low-power wireless sensor nodes powered by RF wireless power transfer. The proposed converter achieves 10% higher power conversion efficiency than a conventional rectifier, with only a 1% increa ...

2024

Simultaneous Quantification of Multiple Drugs by Machine Learning on Electrochemical Sensors

Sandro Carrara

Electrochemical devices and systems are significant for the development of therapeutic drug monitoring (TDM) and personalized therapy. However, electrochemical sensors are usually not that much selective. Therefore, innovative machine learning (ML) approac ...

Institute of Electrical and Electronics Engineers Inc.2024

Eco-Conscious Approach to Wireless Gas Monitoring With a Hybrid Printed Passive Sensor Tag

Sandro Carrara, Johanna Zikulnig, Jürgen Kosel

Addressing the environmental impact of electronic waste in biomedical sensing, an eco-conscious approach to the realization of a Chitosan-based Acetone sensor tag for wireless gas monitoring is presented. The fabrication involves inkjet printing of silver ...

Ieee-Inst Electrical Electronics Engineers Inc2024

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