Publications de Usawadee Sakulkhu

Significance of surface charge and shell material of superparamagnetic iron oxide nanoparticle (SPION) based core/shell nanoparticles on the composition of the protein corona

Heinrich Hofmann, Géraldine Sylvie Coullerez, Morteza Mahmoudi, Usawadee Sakulkhu, Lionel André Maurizi

As nanoparticles (NPs) are increasingly used in many applications their safety and efficient applications in nanomedicine have become concerns. Protein coronas on nanomaterials' surfaces can influence how the cell "recognizes" nanoparticles, as well as the ...

Royal Soc Chemistry2015

Ex situ evaluation of the composition of protein corona of intravenously injected superparamagnetic nanoparticles in rats

Heinrich Hofmann, Morteza Mahmoudi, Usawadee Sakulkhu, Lionel André Maurizi, Marie-Gabrielle Chantal Brigitte Ollivier Beuzelin

It is now well recognized that the surfaces of nanoparticles (NPs) are coated with biomolecules (e. g., proteins) in a biological medium. Although extensive reports have been published on the protein corona at the surface of NPs in vitro, there are very fe ...

Royal Soc Chemistry2014

Syntheses of cross-linked polymeric superparamagnetic beads with tunable properties

Heinrich Hofmann, Vanessa Mai Dao, Usawadee Sakulkhu, Lionel André Maurizi

A novel, rapid and reproducible method to synthesize functionalized magnetic beads with an original shape is presented. By coating Fe2O3 nanoparticles with PVA, it was possible to tune the size, the number of iron oxide nanoparticles encapsulated and the o ...

RSC Publishing2014

Protein Corona Composition of Superparamagnetic Iron Oxide Nanoparticles with Various Physico-Chemical Properties and Coatings

Heinrich Hofmann, Jatuporn Salaklang, Morteza Mahmoudi, Usawadee Sakulkhu, Lionel André Maurizi

Because of their biocompatibility and unique magnetic properties, superparamagnetic iron oxide nanoparticles NPs (SPIONs) are recognized as some of the most prominent agents for theranostic applications. Thus, understanding the interaction of SPIONs with b ...

Nature Publishing Group2014

A fast and reproducible method to quantify magnetic nanoparticle biodistribution

Heinrich Hofmann, Usawadee Sakulkhu, Lionel André Maurizi

The quantification of nanoparticles, particularly superparamagnetic iron oxide nanoparticles (SPIONs), both in vitro and in vivo has become highly important in recent years. Some methods, such as induced coupled plasma (ICP) spectroscopy and UV-visible che ...

Royal Society of Chemistry2014

Preparation of Coated Nanoparticles and Investigation of their Behavior in Biological Environment

Usawadee Sakulkhu

EPFL2013