Publications de Mikaël Nils Sturny

Low-Intensity Electrostimulation Enhances Neuroregeneration and Improves Erectile Function in a Rat Model of Cavernous Nerve Injury

Nikolaos Stergiopoulos, Mikaël Nils Sturny, Rodrigo Araujo Fraga Da Silva

Background: Neurogenic erectile dysfunction (ED) following radical prostatectomy (RP) is a frequent complication often leading to erectile tissue remodeling and permanent ED. Low-intensity electrostimulation (LIES) has been shown to enhance peripheral nerv ...

ELSEVIER SCI LTD2022

Apelin-13 Protects Corpus Cavernosum Against Fibrosis Induced by High-Fat Diet in an MMP-Dependent Mechanism

Nikolaos Stergiopoulos, Rafaela Fernandes Da Silva, Mikaël Nils Sturny, Fabiana Pereira Da Costa Fraga, Léa Liliane Colette Anguenot, Maiia Bragina, Augusto Martins Lima

Background: An increased fibrosis of the corpora cavernosa is a prevalent process that underlies most cases of erectile dysfunction. Apelin, an endogenous circulating peptide, has been documented as an important effector on cardiovascular homeostasis, cont ...

ELSEVIER SCI LTD2021

Low-Intensity Electrostimulation Of Injured Cavernous Nerves Ameliorates Erectile Dysfunction And Promotes Penile Rehabilitation In Rats

Nikolaos Stergiopoulos, Mikaël Nils Sturny, Rodrigo Araujo Fraga Da Silva

ELSEVIER SCI LTD2020

Multidisciplinary Approach to Treat Erectile Dysfunction

Mikaël Nils Sturny

Erectile dysfunction (ED) is a widespread disease affecting approximately 20% of men. With a rising incidence due to the global ageing of the world population, it is estimated that over 322 million patients will be affected in 2025. While not being a lifet ...

EPFL2020

Characterization of the Renin-Angiotensin System in Aged Cavernosal Tissue and its Role in Penile Fibrosis

Nikolaos Stergiopoulos, Mikaël Nils Sturny, Fabiana Pereira Da Costa Fraga, Maiia Bragina, Babak Ebadi Shirmard

Background: The renin-angiotensin system (RAS) plays an important role in erectile function. The RAS contains 2 major axes: one deleterious, composed of ACE-Ang II-AT1 receptor, and another protective, composed of ACE2-Ang-(1-7)-Mas receptor. While aging i ...

ELSEVIER SCI LTD2020

Performance and safety of treatment options for erectile dysfunction in patients with spinal cord injury: A review of the literature

Nikolaos Stergiopoulos, Mikaël Nils Sturny, Rodrigo Araujo Fraga Da Silva

Background For a large proportion of patients with spinal cord injury, sexuality and reproduction are important issues. However, sparse data exist regarding available treatment options for this patient population. Objectives We sought to review performance ...

WILEY2020

Long-Term Low-Intensity Electrostimulation Of Injured Cavernosal Nerve Improves Erectile Function Recovery In A Rat Model Of Postprostatectomy Erectile Dysfunction

Nikolaos Stergiopoulos, Mikaël Nils Sturny, Rodrigo Araujo Fraga Da Silva

ELSEVIER SCI LTD2019

Novel Concept Enabling an Old Idea: A Flexible Electrode Array to Treat Neurogenic Erectile Dysfunction

Nikolaos Stergiopoulos, Mikaël Nils Sturny, Rodrigo Araujo Fraga Da Silva

Introduction: Many studies have shown that electrostimulation of the cavernosal nerve can induce and maintain penile erection. Based on these discoveries, neurostimulation to activate the erectile response has been considered a potential solution to treat ...

ELSEVIER SCI LTD2018

NOVEL CONCEPT TO ENABLE AN OLD IDEA: A FLEXIBLE ELECTRODE ARRAY TO RECOVER NEUROGENIC ERECTILE DYSFUNCTION

Nikolaos Stergiopoulos, Mikaël Nils Sturny

2018

PROTECTIVE EFFECT OF APELIN-13 AGAINST HYPERCHOLESTEROLEMIA-INDUCED FIBROSIS OF THE CORPUS CAVERNOSUM

Nikolaos Stergiopoulos, Rafaela Fernandes Da Silva, Mikaël Nils Sturny, Fabiana Pereira Da Costa Fraga, Léa Liliane Colette Anguenot, Maiia Bragina, Augusto Martins Lima

2018

Apelin-13 Protects Corpus Cavernosum Against Fibrosis Induced By Hypercholesterolemia

Nikolaos Stergiopoulos, Rafaela Fernandes Da Silva, Mikaël Nils Sturny, Fabiana Pereira Da Costa Fraga, Léa Liliane Colette Anguenot

Wiley-Blackwell2016

Diminazene Protects Corpus Cavernosum Against Hypercholesterolemia-Induced Injury

Nikolaos Stergiopoulos, Rafaela Fernandes Da Silva, Younouss Faye, Mikaël Nils Sturny, Fabiana Pereira Da Costa Fraga

IntroductionAngiotensin-converting enzyme 2 (ACE2) is a key enzyme of the renin angiotensin system, which breaks down angiotensin II and forms angiotensin-(1-7). In erectile tissues, it has been documented that angiotensin II contributes to the development ...

Wiley-Blackwell2015

An Increased Arginase Activity Is Associated with Corpus Cavernosum Impairment Induced by Hypercholesterolemia

Nikolaos Stergiopoulos, Younouss Faye, Mikaël Nils Sturny, Fabiana Pereira Da Costa Fraga

IntroductionHypercholesterolemia is a prevalent risk factor for the development of erectile dysfunction (ED), mostly due to an increase in oxidative stress and impaired nitric oxide (NO) bioavailability within the penis. Arginase is an enzyme that shares t ...

Wiley-Blackwell2014

Arginase Inhibition Protects Corpus Cavernosum Against Hypercholesterolemia-Induced Impairment

Nikolaos Stergiopoulos, Rafaela Fernandes Da Silva, Younouss Faye, Mikaël Nils Sturny, Fabiana Pereira Da Costa Fraga

Wiley-Blackwell2014