Publications de Raphaël Jovita De Matos

Gd3+-Functionalized Lithium Niobate Nanoparticles for Dual Multiphoton and Magnetic Resonance Bioimaging

Sandrine Gerber, Anne-Sophie Chauvin, Luigi Bonacina, Marinella Mazzanti, Katarzyna Pierzchala, Raphaël Jovita De Matos, Dario Diviani, Jérémy Vuilleumier, Adrian Stefan Gheata, Ileana Ozana Jelescu, Laura Camille Louise Nicolle, Fiorella Lucarini

Harmonic nanoparticles (HNPs) have emerged as appealing exogenous probes for optical bioimaging due to their distinctive features such as long-term photostability and spectral flexibility, allowing multiphoton excitation in the classical (NIR-I) and extend ...

2022

Surface functionalization of metal oxide harmonic nanoparticles for targeted cancer imaging

Raphaël Jovita De Matos

Cancer is a major health burden worldwide and the leading cause of death in industrialized countries. Early detection is a primary factor of survival and remission rate. Classical imaging methods such as magnetic resonance imaging, ultrasound imaging and m ...

EPFL2020

Photocontrolled release of the anticancer drug chlorambucil with caged harmonic nanoparticles

Jean-Pierre Wolf, Sandrine Gerber, Luigi Bonacina, Raphaël Jovita De Matos, Jérémy Vuilleumier

While chemotherapy is one of the most used treatments in oncology, the systemic administration of chemotherapeutics generally results in undesired damages to healthy tissues and cells, side effects such as severe nausea and leukopenia, and reduced efficacy ...

Wiley-VHCA AG2020

Two-photon triggered photorelease of caged compounds from multifunctional harmonic nanoparticles

Sandrine Gerber, Luigi Bonacina, Daniel Ortiz Trujillo, Laure Menin, Raphaël Jovita De Matos, Jérémy Vuilleumier

The design of stimuli-responsive nanocarriers has raised much attention to achieve higher local concentration of therapeutics and mitigate the appearance of drug resistance. The combination of imaging properties and controlled photorelease of active molecu ...

2019

Inhibitor-conjugated harmonic nanoparticles targeting fibroblast activation protein

Sandrine Gerber, Raphaël Jovita De Matos, Jérémy Vuilleumier

The recent progress in the engineering of nanosized inorganic materials presenting tailored physical properties and reactive surface for post-functionalization has opened promising avenues for the use of nanoparticles (NPs) in diagnosis and therapeutic int ...

2019

The Swiss Summer School in Chemical Biology 2016 in brief

Raphaël Jovita De Matos, Jacques Saarbach, Patrick Andreas Gonschorek

Swiss Chemical Soc2016