Publications de Sebastian James Davis

Measurement of the inclusive and differential t(t)over-bar gamma cross sections in the dilepton channel and effective field theory interpretation in proton-proton collisions at root s=13 TeV

Jean-François Carlin, Rakesh Chawla, Richard Pitts, Arvind Shah, Ian Smith, Randoald Müller, Carlos Andres Peña Reyes, Jung Eung Park, Thomas Mountford, Matthias Finger, Jin Won Seo, Johannes Steen, Josef Andreas Schuler, Olivier Martin, Melody Swartz, Kyumin Lee, Hoang-Trang Lam, Maria Isabel Cordero Campana, Ananda Sankar Roy, Bertrand François, Yogesh Singh Chauhan, Xiaoqiang Wang, Miguel Fernández Ruiz, Sun Hee Kim, Jian Zhao, João Miguel das Neves Duarte, Justin Terence Notz Pekkanen, Joo Yeon Kim, Alexis Kalogeropoulos, Jae-Woo Choi, Pedro Camilo de Oliveira e Silva, Cristopher Ariel Zeballos Avila, Myun Sik Kim, Chao Wang, Yixing Chen, Aravind Kumar Chandiran, Tian Cheng, Ana Margarida Da Costa Ricardo, , , , , , , , , , , ,

Molten globule-like transition state of protein barnase measured with calorimetric force spectroscopy

Sebastian James Davis

Understanding how proteins fold into their native structure is a fundamental problem in biophysics, crucial for protein design. It has been hypothesized that the formation of a molten globule intermediate precedes folding to the native conformation of glob ...

National Academy of Sciences2022

Rhesus Blood Typing within a Few Seconds by Packing-Enhanced Nanoscattering on Individual Erythrocytes

Aleksandra Radenovic, Sebastian James Davis, Po-Ling Chang

A method for the ABO and Rhesus (Rh) blood group typing from individual erythrocytes is proposed in this study. Blood-group-specific antibodies immobilized to gold nanoparticles (BG-AuNP) were utilized for the identification of blood groups from individual ...

AMER CHEMICAL SOC2021

Wetting of nanopores probed with pressure

Aleksandra Radenovic, Sebastian James Davis, Michal Daniel Macha, Sanjin Marion, Andrey Chernev

Nanopores are both a tool to study single-molecule biophysics and nanoscale ion transport, but also a promising material for desalination or osmotic power generation. Understanding the physics underlying ion transport through nano-sized pores allows better ...

ROYAL SOC CHEMISTRY2021

High-Throughput Nanocapillary Filling Enabled by Microwave Radiation for Scanning Ion Conductance Microscopy Imaging

Aleksandra Radenovic, Georg Fantner, Sebastian James Davis, Samuel Mendes Leitão, Sanjin Marion, Vytautas Navikas

Solid-state nanopores provide a highly sensitive tool for single-molecule sensing and probing nanofluidic effects in solutions. Glass nanopipettes are a cheap and robust type of solid-state nanopore produced from pulling glass capillaries with opening orif ...

2020

Pressure-Induced Enlargement and Ionic Current Rectification in Symmetric Nanopores

Aleksandra Radenovic, Sebastian James Davis, Michal Daniel Macha, Sanjin Marion, Andrey Chernev

Nanopores in solid state membranes are a tool able to probe nanofluidic phenomena or can act as a single molecular sensor. They also have diverse applications in filtration, desalination, or osmotic power generation. Many of these applications involve chem ...

2020

Nanocapillary confinement of imidazolium based ionic liquids

Aleksandra Radenovic, Sebastian James Davis, Sanjin Marion, Zeng-Qiang Wu

Room temperature ionic liquids are salts which are molten at or around room temperature without any added solvent or solution. In bulk they exhibit glass like dependence of conductivity with temperature as well as coupling of structural and transport prope ...

2020

Fundamental Applications of Nanopores: Controlled DNA Translocations to Nanofluidics

Sebastian James Davis

Nanopores are nanometer sized openings that are the connection between two electrolyte filled reservoirs. The measurement of the ion transport flowing through such a pore allows to probe physically or biologically interesting phenomena. These range from th ...

EPFL2020

Polymer Coatings to Minimize Protein Adsorption in Solid-State Nanopores

Michael Mayer, Aleksandra Radenovic, Sebastian James Davis, Sanjin Marion

Nanopore-based resistive-pulse recordings represent a promising approach for single-molecule biophysics with applications ranging from rapid DNA and RNA sequencing to "fingerprinting" proteins. Based on advances in fabrication methods, solid-state nanopore ...

WILEY-V C H VERLAG GMBH2020

Single Molecule Localization and Discrimination of DNA–Protein Complexes by Controlled Translocation Through Nanocapillaries

Aleksandra Radenovic, Sebastian Maerkl, Sebastian James Davis, Roman Bulushev, Ekaterina Emilova Petrova, Sanjin Marion

Through the use of optical tweezers we performed controlled translocations of DNA-protein complexes through nanocapillaries. We used RNA polymerase (RNAP) with two binding sites on a 7.2 kbp DNA fragment and a dCas9 protein tailored to have five binding si ...

American Chemical Society (ACS)2016