Etienne Meylan

Cette personne n’est plus à l’EPFL

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Publications associées (30)

Glucose transporters in cancer - from tumor cells to the tumor microenvironment

Caroline Anne-Lyse Contat, Etienne Meylan, Pierre-Benoit Bernard Ancey

Solute carriers of the glucose transporter (GLUT) family mediate the first step for cellular glucose usage. The upregulation of GLUTs has been reported in numerous cancer types as a result of perturbation of gene expression or protein relocalization or sta ...

WILEY2018

Peripheral administration of lactate produces antidepressant-like effects

Pierre Magistretti, Etienne Meylan, Benjamin Boury-Jamot, Anthony Carrard

2017

Osteoblasts remotely supply lung tumors with cancer-promoting SiglecF(high) neutrophils

Etienne Meylan, Ferdinando Pucci, Julien Robert Rémi Faget

Bone marrow-derived myeloid cells can accumulate within tumors and foster cancer outgrowth. Local immune-neoplastic interactions have been intensively investigated, but the contribution of the systemic host environment to tumor growth remains poorly unders ...

American Association for the Advancement of Science2017

RIP4 inhibits STAT3 signaling to sustain lung adenocarcinoma differentiation

Paolo Angelino, Mauro Delorenzi, Nadine Fournier, Etienne Meylan, Johanna Pauline Chiffelle, Jawahar Kopparam, Alessandra Piersigilli

Loss of epithelial differentiation and extracellular matrix (ECM) remodeling are known to facilitate cancer progression and are associated with poor prognosis in patients with lung cancer. We have identified Receptor-interacting serine/threonine protein ki ...

Nature Publishing Group2017

Mutant CTNNB1 and histological heterogeneity define metabolic subtypes of hepatoblastoma

Paolo Angelino, Olivier Michielin, Mauro Delorenzi, Etienne Meylan, Jessica Christine Vazquez, Stefania Crippa, Pierre-Benoit Bernard Ancey

Hepatoblastoma is the most common malignant pediatric liver cancer. Histological evaluation of tumor biopsies is used to distinguish among the different subtypes of hepatoblastoma, with fetal and embryonal representing the two main epithelial components. W ...

2017

Neutrophils and Snail Orchestrate the Establishment of a Pro-tumor Microenvironment in Lung Cancer

Nicolas Jean Philippe Guex, Miguel Garcia, Nadine Fournier, Etienne Meylan, Loïc Steiner, Alessandra Piersigilli, Julien Robert Rémi Faget, Svenja Johanna Groeneveld, Gael Luis Boivin, Ioannis Xenarios, Inti Zlobec

Understanding the immune compartment of tumors facilitates the development of revolutionary new therapies. We used a Kras(G12D)-driven mouse model of lung cancer to establish an immune signature and identified a contribution of Gr1 + neutrophils to disease ...

Cell Press2017

RIP off STAT3 to counteract tumor progression

Etienne Meylan, Jawahar Kopparam

Landes Bioscience2017

GLUT3 is induced during epithelial-mesenchymal transition and promotes tumor cell proliferation in non-small cell lung cancer

Mark Jonathan Masin, Bart Deplancke, Etienne Meylan, Jessica Christine Vazquez, Natasha Ella Samson, Petra Catalina Schwalie, Svenja Johanna Groeneveld

Alterations in glucose metabolism and epithelial-mesenchymal transition (EMT) constitute two important characteristics of carcinoma progression toward invasive cancer. Despite an extensive characterization of each of them separately, the links between EMT ...

2014

Targeting receptor activator of nuclear factor-kappa B as a new therapy for bone metastasis in non-small cell lung cancer

Etienne Meylan

Purpose of review The review aims at comprehensively discussing our current knowledge on bone metastases incidence in non-small cell lung cancer (NSCLC), their related complications as well as clinical impact in patients suffering from advanced disease. Re ...

Lippincott Williams & Wilkins2013

Regulation of Monocyte Functional Heterogeneity by miR-146a and Relb

Martin Etzrodt, Pedro Romero, Etienne Meylan

Monocytes serve as a central defense system against infection and injury but can also promote pathological inflammatory responses. Considering the evidence that monocytes exist in at least two subsets committed to divergent functions, we investigated wheth ...

Elsevier2012

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