Emel Basak Gencer Akçok, Oliver Hantschel, Sandrine Madeleine Suzanne Georgeon
The dysregulated tyrosine kinase BCR-ABL causes chronic myelogenous leukemia in humans and forms a large multiprotein complex that includes the Src-homology 2 (SH2) domain-containing phosphatase 2 (SHP2). The expression of SHP2 is necessary for BCR-ABL-dep ...
National Academy of Sciences2013