Publications de Mathieu Künzi

In Vivo Retinal Pigment Epithelium Imaging using Transscleral Optical Imaging in Healthy Eyes

Christophe Moser, Mathieu Künzi, Timothé Laforest, Laura Emmanuelle Kowalczuk

Objective: To image healthy retinal pigment epithelial (RPE) cells in vivo using Transscleral OPtical Imaging (TOPI) and to analyze statistics of RPE cell features as a function of age, axial length (AL), and eccentricity. Design: Single-center, explorator ...

ELSEVIER2022

Human retinal pigment epithelium cells can be imaged in vivo with a novel adaptive optics camera using transscleral illumination

Christophe Moser, Mathieu Künzi, Timothé Laforest, Laura Emmanuelle Kowalczuk

ASSOC RESEARCH VISION OPHTHALMOLOGY INC2022

Multi-modal retinal imaging platform

Christophe Moser, Mathieu Künzi, Timothé Laforest

The invention relates to oblique transscleral illumination of an eye fundus with at least one physical point light source around the eye allowing for dark field imaging combined with optical coherence tomography imaging. ...

2021

Transscleral optical phase imaging in non-neovascular age-related macular degeneration

Christophe Moser, Mathieu Künzi, Timothé Laforest, Laura Emmanuelle Kowalczuk

ASSOC RESEARCH VISION OPHTHALMOLOGY INC2021

Transscleral optical phase imaging revealing the choriocapillaris structure

Christophe Moser, Mathieu Künzi, Timothé Laforest

ASSOC RESEARCH VISION OPHTHALMOLOGY INC2021

Transscleral Optical Phase Imaging of healthy human Retinal Pigment Epithelium

Christophe Moser, Mathieu Künzi, Timothé Laforest, Laura Emmanuelle Kowalczuk

ASSOC RESEARCH VISION OPHTHALMOLOGY INC2021

Optical phase contrast imaging of human retinal cells by changing the tissue refractive index

Christophe Moser, Mathieu Künzi, Timothé Laforest, Laura Emmanuelle Kowalczuk

Purpose : Based on oblique partially coherent illumination of transparent samples, we developed a simple custom Optical Phase Imaging (OPI) microscope providing a label-free, semi-quantitative phase contrast imaging. The aim of this study was to explore th ...

ASSOC RESEARCH VISION OPHTHALMOLOGY INC2020

Ophthalmic system and method for clinical device using transcleral illumination with multiple points source

Christophe Moser, Mathieu Künzi, Timothé Laforest

An ophthalmic illumination and imaging system with transscleral / transpalpebral illumination of the eye fundus comprises a light-delivering device with a plurality of emitting areas; each of the emitting areas being configured to be independently controll ...

2020

Phase sensitivity in differential phase contrast microscopy: limits and strategies to improve it

Christophe Moser, Mathieu Künzi, Timothé Laforest, Chiara Bonati

The phase sensitivity limit of Differential Phase Contrast (DPC) with partially coherent light is analyzed in details. The parameters to tune phase sensitivity, such as the diameter of illumination, the numerical aperture of the objective, and the noise of ...

2020

Transscleral optical phase imaging (TOPI) of human retinal pigment epithelium

Christophe Moser, Mathieu Künzi, Timothé Laforest, Laura Emmanuelle Kowalczuk

ASSOC RESEARCH VISION OPHTHALMOLOGY INC2019

Phase imaging of retinal cells for clinical studies and diagnosis

Christophe Moser, Mathieu Künzi, Dino Carpentras, Timothé Laforest, Laura Emmanuelle Kowalczuk

ASSOC RESEARCH VISION OPHTHALMOLOGY INC2018

System, method and apparatus for retinal absorption phase and dark field imaging with oblique illumination

Christophe Moser, Mathieu Künzi, Dino Carpentras, Timothé Laforest

A method for imaging a tissue of an eye, the method including the steps of providing oblique illumination to the eye by a plurality of light emitting areas of a light delivery device, the plurality of light emitting areas being independently controllable a ...

2017