Publications de Sviatlana Siankevich

The Prembion (R) pre-biotic improves the impact of anti-CTLA4 immune checkpoint inhibitor in a murine model of malignant pleural mesothelioma

Paul Joseph Dyson, Sviatlana Siankevich, Yan Hao

OXFORD UNIV PRESS2022

Discovery of a Highly Active Catalyst for Hydrogenolysis of C-O Bonds via Systematic, Multi-metallic Catalyst Screening

Paul Joseph Dyson, Ning Yan, Antoine Philippe Van Muyden, Sviatlana Siankevich

Hydrogenolysis of C-O bonds is a highly challenging reaction with the most efficient catalysts based on bimetallic assemblies. Systematic studies to identify the optimum metal combination have not been performed and, therefore, we designed a method to scre ...

Wiley-VCH Verlag2019

Efficient cleavage of aryl ether C–O linkages by Rh–Ni and Ru–Ni nanoscale catalysts operating in water

Paul Joseph Dyson, Vassily Hatzimanikatis, Duncan Thomas Lindsay Alexander, Ning Yan, Antoine Philippe Van Muyden, Safak Bulut, Georgios Savoglidis, Sviatlana Siankevich

Bimetallic Ru–Ni and Rh–Ni nanocatalysts coated with a phase transfer agent efficiently cleave aryl ether C–O linkages in water in the presence of hydrogen. For dimeric substrates with weaker C–O linkages, i.e. α-O-4 and β-O-4 bonds, low loadings of the pr ...

2018

Influence of the Anion on the Oxidation of 5-Hydroxy-methylfurfural by Using Ionic-Polymer-Supported Platinum Nanoparticle Catalysts

Paul Joseph Dyson, Zhaofu Fei, Ning Yan, Felix Daniel Bobbink, Simone Mozzettini, Sviatlana Siankevich

Platinum nanoparticles stabilized by an imidazolium-based cross-linked polymer (with chloride as the counteranion) efficiently catalyzed the oxidation of 5-hydroxymethylfurfural to form 2,5-furandicarboxylic acid in water under mild conditions with oxygen ...

2018

Ionic polymers and use thereof in processing of biomass

Paul Joseph Dyson, Zhaofu Fei, Georgios Savoglidis, Sviatlana Siankevich

The invention provides ionic polymers (IP) consisting of anions and a polymeric backbone containing cations. The invention also provides the ionic polymers incorporated in membranes or attached to solid supports and use of the ionic polymers in processing ...

2017

Direct Conversion of Mono- and Polysaccharides into 5-Hydroxymethylfurfural Using Ionic-Liquid Mixtures

Rosario Scopelliti, Paul Joseph Dyson, Zhaofu Fei, Ning Yan, Sviatlana Siankevich, Philip Gregory Jessop

Platform chemicals are usually derived from petrochemical feedstocks. A sustainable alternative commences with lignocellulosic biomass, a renewable feedstock, but one that is highly challenging to process. Ionic liquids (ILs) are able to solubilize biomass ...

Wiley-VCH Verlag Berlin2016

Conversion of biomass into value-added chemicals

Sviatlana Siankevich

Green house gas emissions, the depleting of non-renewable resources, and poor waste management have a detrimental environmental and socioeconomic impact. Consequantly, the development of alternative processes that alleviate these problems is imperative. Ap ...

EPFL2016

Application of Ionic Liquids in the Downstream Processing of Lignocellulosic Biomass

Paul Joseph Dyson, Zhaofu Fei, Ning Yan, Sviatlana Siankevich

Chemical transformations of lignocellulosic substrates to valuable platform chemicals are challenging as lignin and cellulose have high thermal and chemical stabilities. However, certain ionic liquids are able to dissolve and deconstruct biomass and, in th ...

Schweizerische Chemische Gesellschaft2015

Quantification of Conventional and Nonconventional Charge-Assisted Hydrogen Bonds in the Condensed and Gas Phases

Rosario Scopelliti, Paul Joseph Dyson, Zhaofu Fei, Sviatlana Siankevich

Charge-assisted hydrogen bonds (CAHBs) play critical roles in many systems from biology through to materials. In none of these areas has the role and function of CAHBs been explored satisfactorily because of the lack of data on the energy of CAHBs in the c ...

Amer Chemical Soc2015

Aqueous-phase hydrogenation of alkenes and arenes: The growing role of nano scale catalysts

Paul Joseph Dyson, Zhaofu Fei, Ning Yan, Safak Bulut, Sviatlana Siankevich

In this article we highlight some of the recent developments in the aqueous-phase hydrogenation of alkenes and arenes. The traditional types of water-soluble catalysts applied in aqueous media are outlined together with recent trends towards the developmen ...

Elsevier Science Bv2015

A novel platinum nanocatalyst for the oxidation of 5-Hydroxymethylfurfural into 2,5-Furandicarboxylic acid under mild conditions

Gabor Laurenczy, Paul Joseph Dyson, Zhaofu Fei, Duncan Thomas Lindsay Alexander, Ning Yan, Georgios Savoglidis, Sviatlana Siankevich

5-Hydroxymethylfurfural (HMF) is a key intermediate obtainable from various cellulosic (biomass) derivatives, but it must be converted to other chemicals such as 2,5-Furandicarboxylic acid (FDCA) for direct use. FDCA is an important derivative of HMF as it ...

Academic Press Inc Elsevier Science2014

Potential of Cycloaddition Reactions To Generate Cytotoxic Metal Drugs In Vitro

Paul Joseph Dyson, Stéphanie Crot, Benjamin Samuel Murray, Sviatlana Siankevich

Severe general toxicity issues blight many chemotherapeutics utilized in the treatment of cancers, resulting in the need for more selective drugs able to exert their biological activity at only the required location(s). Toward this aim, we report the devel ...

Amer Chemical Soc2014

Enhanced Conversion of Carbohydrates to the Platform Chemical 5-Hydroxymethylfurfural Using Designer Ionic Liquids

Gabor Laurenczy, Rosario Scopelliti, Paul Joseph Dyson, Zhaofu Fei, Ning Yan, Sviatlana Siankevich

5-Hydroxymethylfurfural (HMF) is a key platform chemical that may be obtained from various cellulosic (biomass) derivatives. Previously, it has been shown that ionic liquids (ILs) facilitate the catalytic conversion of glucose into HMF. Herein, we demonstr ...

Wiley-V C H Verlag Gmbh2014