Publications de Cornelis Ulrich Lütgebaucks

Three-Dimensional Confinement of Water: H2O Exhibits Long-Range (> 50 nm) Structure while D2O Does Not

Sylvie Roke, Nathan Dupertuis, Cornelis Ulrich Lütgebaucks, Orly Bagunu Tarun

Water is the liquid of life thanks to its three-dimensional adaptive hydrogen (H)-bond network. Confinement of this network may lead to dramatic structural changes influencing chemical and physical transformations. Although confinement effects occur on a < ...

AMER CHEMICAL SOC2022

Surface Characterization of Colloidal Silica Nanoparticles by Second Harmonic Scattering: Quantifying the Surface Potential and Interfacial Water Order

Arianna Marchioro, Sylvie Roke, Cornelis Ulrich Lütgebaucks, Marie Bischoff

The microscopic description of the interface of colloidal particles in solution is essential to understand and predict the stability of these systems, as well as their chemical and electrochemical reactivity. However, this description often relies on the u ...

2019

Kinetically Stable Triglyceride-Based Nanodroplets and Their Interactions with Lipid-Specific Proteins

Sylvie Roke, Cornelis Ulrich Lütgebaucks, Halil Ibrahim Okur

2018

Intermolecular headgroup interaction and hydration as driving forces for lipid transmembrane asymmetry

Sylvie Roke, Cornelis Ulrich Lütgebaucks, Nikolay Smolentsev, Halil Ibrahim Okur

ACS2018

Optical label- and model-free probing of the surface potential of nanoscale silica particles in aqueous solution

Arianna Marchioro, Sylvie Roke, Cornelis Ulrich Lütgebaucks

AMER CHEMICAL SOC2018

Zwitterionic and Charged Lipids Form Remarkably Different Structures on Nanoscale Oil Droplets in Aqueous Solution

Yixing Chen, Sylvie Roke, Cornelis Ulrich Lütgebaucks, Halil Ibrahim Okur

2018

Characterization of the interface of binary mixed DOPC:DOPS liposomes in water: The impact of charge condensation

Sylvie Roke, Cornelis Ulrich Lütgebaucks, Carlos Alberto Macias Romero

Solutions of liposomes composed of binary mixtures of anionic dioleoylphosphatidylserine (DOPS) and zwitterionic dioleoylphosphatidylcholine (DOPC) are investigated with label-free angle-resolved (AR) second harmonic scattering (SHS) and electrophoretic mo ...

2017

Lipid membrane characterization with second harmonic scattering : surface potentials, ionization, membrane asymmetry and hydration

Cornelis Ulrich Lütgebaucks

Membranes, composed of a variety of lipids and other biomolecules, mediate signaling processes between cells and their aqueous environment. To fulfill this function, membranes can vary their composition leaflet-specific and thus alter their surface propert ...

EPFL2017

Optical label-free and model-free probe of the surface potential of nanoscale and microscopic objects in aqueous solution

Sylvie Roke, Cornelis Ulrich Lütgebaucks

The electrostatic environment of aqueous systems is an essential ingredient for the function of any living system. To understand the electrostatic properties and their molecular foundation in soft, living, and three-dimensional systems, we developed a tabl ...

Amer Physical Soc2016

Intermolecular Headgroup Interaction and Hydration as Driving Forces for Lipid Transmembrane Asymmetry

Sylvie Roke, Cornelis Ulrich Lütgebaucks, Nikolay Smolentsev, Halil Ibrahim Okur

Variations between the inner and outer leaflets of cell membranes are crucial for cell functioning and signaling, drug–membrane interactions, and the formation of lipid domains. Transmembrane asymmetry can in principle be comprised of an asymmetric charge ...

American Chemical Society2016

Second Harmonic and Sum-Frequency Generation from Aqueous Interfaces Is Modulated by Interference

Sylvie Roke, Cornelis Ulrich Lütgebaucks

The interfacial region of aqueous systems also known as the electrical double layer can be characterized on the molecular level with second harmonic and sum-frequency generation (SHG/SFG). SHG and SFG are surface specific methods for isotropic liquids. Her ...

American Chemical Society2016

Three Dimensional Nano "Langmuir Trough" for Lipid Studies

Yixing Chen, Sylvie Roke, Kailash Chandra Jena, Cornelis Ulrich Lütgebaucks, Halil Ibrahim Okur

A three-dimensional-phospholipid monolayer with tunable molecular structure was created on the surface of oil nanodroplets from a mixture of phospholipids, oil, and water. This simple nanoemulsion preparation technique generates an in situ prepared membran ...

Amer Chemical Soc2015