Publications de Maude Schneider

Agency Deficits in a Human Genetic Model of Schizophrenia: Insights From 22q11DS Patients

Olaf Blanke, Oliver Alan Kannape, Mariia Kaliuzhna, Roy Salomon, Maude Schneider, Henrique Galvan Debarba, Nathan Quentin Faivre

Schizophrenia is a chronic and disabling mental illness characterized by a disordered sense of self. Current theories suggest that deficiencies in the sense of control over one’s actions (Sense of Agency, SoA) may underlie some of the symptoms of schizophr ...

2022

Exploring associations between diurnal cortisol, stress, coping and psychopathology in adolescents and young adults with 22q11.2 deletion syndrome

Maria del Carmen Sandi Perez, Olivia Zanoletti, Maude Schneider, Farnaz Delavari

Background: 22q11.2 deletion syndrome (22q11DS) is a neurogenetic condition associated to a high risk for psychiatric disorders, including psychosis. Individuals with 22q11DS are thought to experience increased levels of chronic stress, which could lead to ...

2022

Dysmaturation Observed as Altered Hippocampal Functional Connectivity at Rest Is Associated With the Emergence of Positive Psychotic Symptoms in Patients With 22q11 Deletion Syndrome

Dimitri Nestor Alice Van De Ville, Maude Schneider, Daniela Maria Zöller, Karin Bortolin, Farnaz Delavari

BACKGROUND: Hippocampal alterations are among the most replicated neuroimaging findings across the psychosis spectrum. Moreover, there is strong translational evidence that preserving the maturation of hippocampal networks in mice models prevents the progr ...

ELSEVIER SCIENCE INC2021

Characterization and prediction of clinical pathways of vulnerability to psychosis through graph signal processing

Dimitri Nestor Alice Van De Ville, Maude Schneider, Anjali Bagunu Tarun, Daniela Maria Zöller

Causal interactions between specific psychiatric symptoms could contribute to the heterogenous clinical trajectories observed in early psychopathology. Current diagnostic approaches merge clinical manifestations that co-occur across subjects and could sign ...

eLIFE SCIENCES PUBL LTD2021

Identifying neurodevelopmental anomalies of white matter microstructure associated with high risk for psychosis in 22q11.2DS

Marie Schaer, Maude Schneider, Maria Carmela Padula, Daniela Maria Zöller

Disruptions of white matter microstructure have been widely reported in schizophrenia. However, the emergence of these alterations during preclinical stages remains poorly understood. 22q11.2 Deletion Syndrome (22q11.2DS) represents a unique model to study ...

SPRINGERNATURE2020

Long-term verbal memory deficit and associated hippocampal alterations in 22q11.2 deletion syndrome

Maude Schneider, Daniela Maria Zöller

Chromosome 22q11.2 deletion syndrome (22q11.2DS) is a genetic disease associated with an increased risk for schizophrenia and a specific cognitive profile. In this paper, we challenge the current view of spared verbal memory in 22q11.2DS by investigating v ...

2020

Robot-Induced Mild Hallucinations And Passivity Experiences In Individuals With The 22Q11.2 Deletion Syndrome

Olaf Blanke, Laurent Frédéric Jenni, Eva Blondiaux, Maude Schneider, Fosco Bernasconi, Jevita Potheegadoo, Giedre Stripeikyte

OXFORD UNIV PRESS2020

Pituitary dysmaturation affects psychopathology and neurodevelopment in 22q11.2 Deletion Syndrome

Dimitri Nestor Alice Van De Ville, Maria del Carmen Sandi Perez, Marie Schaer, Maude Schneider, Maëlle Chambaz, Daniela Maria Zöller

Background 22q11.2 Deletion Syndrome (22q11DS) confers strongly increased genetic risk for multiple psychiatric disorders. Similarly to the general population, rates of psychiatric comorbidity suggest that common disease mechanisms are shared across dimens ...

2020

Development of Structural Covariance From Childhood to Adolescence: A Longitudinal Study in 22q11.2DS

Dimitri Nestor Alice Van De Ville, Maude Schneider, Maria Carmela Padula, Daniela Maria Zöller

2018

Psychotic symptoms influence the development of anterior cingulate BOLD variability in 22q11.2 deletion syndrome

Dimitri Nestor Alice Van De Ville, Maude Schneider, Maria Carmela Padula, Daniela Maria Zöller

2018

Cortical Dysconnectivity Measured by Structural Covariance Is Associated With the Presence of Psychotic Symptoms in 22q11.2 Deletion Syndrome

Dimitri Nestor Alice Van De Ville, Marie Schaer, Maude Schneider, Maria Carmela Padula

BACKGROUND: 22q11.2 deletion syndrome (22q11DS) is the third-largest known genetic risk factor for the development of psychosis. Dysconnectivity has consistently been implicated in the physiopathology of psychosis. Structural covariance of cortical morphol ...

2018

Cortical morphology development in patients with 22q11.2 deletion syndrome at ultra-high risk of psychosis

Marie Schaer, Maude Schneider, Maria Carmela Padula, Daniela Maria Zöller

Background. Patients with 22q11.2 deletion syndrome (22q11DS) present a high risk of developing psychosis. While clinical and cognitive predictors for the conversion towards a full-blown psychotic disorder are well defined and largely used in practice, neu ...

CAMBRIDGE UNIV PRESS2018

Schizophrenia patients and 22q11.2 deletion syndrome adolescents at risk express the same deviant patterns of resting state EEG microstates: A candidate endophenotype of schizophrenia

Dimitri Nestor Alice Van De Ville, Michael Herzog, Fikret Isik Karahanoglu, Maya Roinishvili, Maude Schneider

Schizophrenia is a complex psychiatric disorder and many of the factors contributing to its pathogenesis are poorly understood. In addition, identifying reliable neurophysiological markers would improve diagnosis and early identification of this disease. T ...

2015

Comparing the neural bases of self-referential processing in typically developing and 22q11.2 adolescents

Roy Salomon, Maude Schneider

The investigation of self-reflective processing during adolescence is relevant, as this period is characterized by deep reorganization of the self-concept. It may be the case that an atypical development of brain regions underlying self-reflective processi ...

Elsevier Sci Ltd2012

Resting-state networks in adolescents with 22q11.2 deletion syndrome: Associations with prodromal symptoms and executive functions

Dimitri Nestor Alice Van De Ville, Maude Schneider

Atypical functional connectivity in the maturing brains of 22q11.2 deletion syndrome (22q11DS) may contribute to the expression of early psychotic symptoms commonly reported by these youths. This study's objective was to examine functional connectivity in ...

Elsevier2012

Regional cortical volumes and congenital heart disease: a MRI study in 22q11.2 deletion syndrome

Jean-Philippe Thiran, Meritxell Bach Cuadra, Marie Schaer, Maude Schneider

Children with congenital heart disease (CHD) who survive surgery often present impaired neurodevelopment and qualitative brain anomalies. However, the impact of CHD on total or regional brain volumes only received little attention. We address this question ...

2010