Eduardo Martin Moraud

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Publications associées (27)

System to deliver adaptive epidural and/or subdural electrical spinal cord stimulation to facilitate and restore locomotion after a neuromotor impairment

Silvestro Micera, Grégoire Courtine, Nikolaus Wenger, Marco Bonizzato, Eduardo Martin Moraud

The present invention provides a closed-loop system for real-time control of epidural and/or subdural electrical stimulation comprising: means for applying to a subject neuromodulation with adjustable stimulation parameters, said means being operatively co ...

2016

Neuroprosthetic technologies to augment the impact of neurorehabilitation after spinal cord injury

Silvestro Micera, Grégoire Courtine, Joachim von Zitzewitz, Rubia van den Brand, Eduardo Martin Moraud, Marco Capogrosso, Jean-Baptiste Mignardot, Nicolas Francis Fumeaux, Fabien Bertrand Paul Wagner, Jocelyne Bloch

Spinal cord injury leads to a range of disabilities, including limitations in locomotor activity, that seriously diminish the patients’ autonomy and quality of life. Electrochemical neuromodulation therapies, robot-assisted rehabilitation and willpower-bas ...

2015

Biomaterials. Electronic dura mater for long-term multimodal neural interfaces

Tomislav Milekovic, Léonie Asboth, Jérôme Gandar, Nicolas Vachicouras, Stéphanie Lacour, Arthur Edouard Hirsch, Silvestro Micera, Grégoire Courtine, Nikolaus Wenger, Ivan Rusev Minev, Quentin Barraud, Simone Ellen Joze Duis, Eduardo Martin Moraud, Pavel Musienko, Marco Capogrosso, Natalia Pavlova

The mechanical mismatch between soft neural tissues and stiff neural implants hinders the long-term performance of implantable neuroprostheses. Here, we designed and fabricated soft neural implants with the shape and elasticity of dura mater, the protectiv ...

American Association for the Advancement of Science2015

Corticospinal neuroprostheses to restore locomotion after spinal cord injury

José del Rocio Millán Ruiz, Stéphanie Lacour, Silvestro Micera, Grégoire Courtine, Nikolaus Wenger, Ivan Rusev Minev, Marco Bonizzato, Janine Beauparlant, Eduardo Martin Moraud, Pavel Musienko, David Allenson Borton

In this conceptual review, we highlight our strategy for, and progress in the development of corticospinal neuroprostheses for restoring locomotor functions and promoting neural repair after thoracic spinal cord injury in experimental animal models. We spe ...

Elsevier2014

Closed-loop neuromodulation of spinal sensorimotor circuits controls refined locomotion after complete spinal cord injury

Silvestro Micera, Grégoire Courtine, Nikolaus Wenger, Stanisa Raspopovic, Marco Bonizzato, Eduardo Martin Moraud, Pavel Musienko

Neuromodulation of spinal sensorimotor circuits improves motor control in animal models and humans with spinal cord injury. With common neuromodulation devices, electrical stimulation parameters are tuned manually and remain constant during movement. We de ...

American Association for the Advancement of Science2014

A real-time platform for studying the modulatory capacity of epidural stimulation after spinal cord injury

Jérôme Gandar, Silvestro Micera, Grégoire Courtine, Nikolaus Wenger, Eduardo Martin Moraud, Pavel Musienko

Epidural electrical stimulation (EES) showed promises to improve standing and walking after neurological disorders. To date, EES has been delivered continuously, although time-dependent stimulations would likely be more efficient to activate specific subse ...

Ieee2013

Restoring Voluntary Control of Locomotion after Paralyzing Spinal Cord Injury

Silvestro Micera, Grégoire Courtine, Lucia Florinda Friedli Wittler, Rubia van den Brand, Quentin Barraud, Kay Alexander Bartholdi, Simone Ellen Joze Duis, Eduardo Martin Moraud, Isabel Laura Vollenweider, Pavel Musienko

Half of human spinal cord injuries lead to chronic paralysis. Here, we introduce an electrochemical neuroprosthesis and a robotic postural interface designed to encourage supraspinally-mediated movements in rats with paralyzing lesions. Despite the interru ...

American Association for the Advancement of Science2012

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