Publications de Matteo Gregorio Modesto Marascio

Decellularised tissues obtained by a CO2-philic detergent and supercritical CO2

Dominique Pioletti, Pierre-Etienne Bourban, Nathalie Hirt-Burri, Matteo Gregorio Modesto Marascio, Jens Antons, Pierre-Arnaud Aeberhard, Giulia Weissenberger

Tissue decellularisation has gained much attention in regenerative medicine as an alternative to synthetic materials. In decellularised tissues, biological cues can be maintained and provide cellular environments still unmet by synthetic materials. Supercr ...

2018

Depth-dependent mechanical properties of human articular cartilage obtained by indentation measurements

Pierre-Etienne Bourban, Lee Ann Laurent-Applegate, Matteo Gregorio Modesto Marascio, Jens Antons, Robin Martin

Emerging 3D printing technology permits innovative approaches to manufacture cartilage scaffolds associated with layer-by-layer mechanical property adaptation. However, information about gradients of mechanical properties in human articular cartilage is li ...

2018

Hierarchical porous structure

Dominique Pioletti, Pierre-Etienne Bourban, Matteo Gregorio Modesto Marascio

Cellular thermoplastic structures with hierarchical multi-scale porosity (preferably 1-300 µm micro-porosity to 0.3-10 mm macro-porosity) are produced from an integrated approach of 3D printing, preferably by Fused Deposition Modeling (FDM), and of supercr ...

2018

3D Printing and Supercritical Foaming of Hierarchical Cellular Materials

Matteo Gregorio Modesto Marascio

Hierarchical porous structures have been gathering interest in different fields owing to their unique properties associated with their multi-scale features. The observation of natural materials brought new insights into the functionality of cellular materi ...

EPFL2018

Scaffold requirements for periodontal regeneration with enamel matrix derivative proteins

John Christopher Plummer, Laurent Mirko Dejace, Peter Fischer, Alessandra Apicella, Matteo Gregorio Modesto Marascio

Periodontitis affects the attachment of natural teeth, and infection or inflammation associated with periodontitis may affect peri-implant tissues. Enamel matrix derivative (EMD) proteins provide stimulation for self-regeneration of the damaged tissue when ...

Elsevier Science Bv2017

3D Printing of Polymers with Hierarchical Continuous Porosity

Dominique Pioletti, Pierre-Etienne Bourban, Matteo Gregorio Modesto Marascio, Jens Antons

Cellular thermoplastic structures with multiscale porosity (1–300 µm microporosity to 0.3–10 mm macroporosity) are produced from an integrated approach of 3D printing by Fused Deposition Modeling printing and Supercritical CO2 Foaming. Porous strands and r ...

Wiley2017

Molecular dynamics simulations of the intrinsically disordered protein amelogenin

John Christopher Plummer, Alessandra Apicella, Matteo Gregorio Modesto Marascio, Vincenzo Colangelo

Amelogenin refers to a class of intrinsically disordered proteins that are the major constituents of enamel matrix derivative (EMD), an extract of porcine fetal teeth used in regenerative periodontal therapy. Modifications in molecular conformation induced ...

Taylor & Francis Inc2017

The Influence of Arginine on the Response of Enamel Matrix Derivative (EMD) Proteins to Thermal Stress: Towards Improving the Stability of EMD-Based Products

John Christopher Plummer, Raffaele Mezzenga, Peter Fischer, Alessandra Apicella, Matteo Gregorio Modesto Marascio

In a current procedure for periodontal tissue regeneration, enamel matrix derivative (EMD), which is the active component, is mixed with a propylene glycol alginate (PGA) gel carrier and applied directly to the periodontal defect. Exposure of EMD to physio ...

Public Library Science2015