Publications de Frédérica Schyrr

MarrowQuant 2.0: A Digital Pathology Workflow Assisting Bone Marrow Evaluation in Experimental and Clinical Hematology

Olivier Burri, Giovanna Ambrosini, Bart Deplancke, Arne Seitz, Olaia Maria Naveiras Torres-Quiroga, Frédérica Schyrr, Rita Sarkis, Mariangela Costanza, Martin Weigert

2023

The Bile Acid Receptor Tgr5 Regulates The Composition And Hematopoietic Support Capacity Of The Bone Marrow Microenvironment

Kristina Schoonjans, Frédérica Schyrr, Alessia Perino, Alejandro Alonso Calleja, Antoine Jalil

ELSEVIER SCIENCE INC2023

The bile acid receptor TGR5 regulates the hematopoietic support capacity of the bone marrow niche

Dominique Pioletti, Kristina Schoonjans, Ulrike Kettenberger, Frédérica Schyrr, Alessia Perino, Alejandro Alonso Calleja, Antoine Jalil

Smw Supporting Association2023

Induction of mitochondrial recycling reverts age-associated decline of the hematopoietic and immune systems

Johan Auwerx, Olaia Maria Naveiras Torres-Quiroga, Frédérica Schyrr, Charles Christopher Bataclan

Aging compromises hematopoietic and immune system functions, making older adults especially susceptible to hematopoietic failure, infections and tumor development, and thus representing an important medical target for a broad range of diseases. During agin ...

SPRINGERNATURE2023

New approaches to uncover the minimally functional hematopoietic niche using the adipocytic differentiation axis: pharmacological modulation and adrenal niche induction

Frédérica Schyrr

Hematopoietic Stem and Progenitor Cells (HSPCs) reside in their niche, a structure that regulates the balance of cellular quiescence, self-renewal and commitment towards differentiated cells. This highly plastic niche is formed by several cellular players, ...

EPFL2022

Differential Blood Counts Do Not Consistently Predict Clinical Measurements of Bone Mineral Density and Microarchitecture at Homeostasis

Olaia Maria Naveiras Torres-Quiroga, Frédérica Schyrr

The hematopoietic stem cell niche constitutes a complex bone marrow (BM) microenvironment. Osteoporosis is characterized by both reduced bone mineral density (BMD) and microarchitectural deterioration, constituting the most frequent alteration of the BM mi ...

WILEY2022

MarrowQuantAcross Aging and Aplasia: A Digital Pathology Workflow for Quantification of Bone Marrow Compartments in Histological Sections

Nicolas Kunz, Olivier Burri, Olaia Maria Naveiras Torres-Quiroga, Vasco Ledebur de Antas de Campos, Chiheb Boussema, Frédérica Schyrr, Josefine Catharina Pedersen Tratwal, Shanti Rojas-Sutterlin, Rita Sarkis, Daniel Naveed Tavakol

The bone marrow (BM) exists heterogeneously as hematopoietic/red or adipocytic/yellow marrow depending on skeletal location, age, and physiological condition. Mouse models and patients undergoing radio/chemotherapy or suffering acute BM failure endure rapi ...

2020

MarrowQuant across Aging and Aplasia: A Digital Pathology Tool for Quantification of Bone Marrow Compartments in Histological Sections

Nicolas Kunz, Olivier Burri, Olaia Maria Naveiras Torres-Quiroga, Vasco Ledebur de Antas de Campos, Frédérica Schyrr, Josefine Catharina Pedersen Tratwal, Shanti Rojas-Sutterlin, Rita Sarkis

WILEY2020

Blood cell production is not influenced by bone health status in homoeostasis - the CoLaus/OsteoLaus cohort

Olaia Maria Naveiras Torres-Quiroga, Frédérica Schyrr

E M H SWISS MEDICAL PUBLISHERS LTD2019

Correlation study between osteoporosis and hematopoiesis in the context of adjuvant chemotherapy for breast cancer

Olaia Maria Naveiras Torres-Quiroga, Frédérica Schyrr

Springer Verlag2018