Publications de Svenja Johanna Groeneveld

Neutrophils and Snail orchestrate the establishment of a protumor microenvironment in lung adenocarcinoma

Nicolas Jean Philippe Guex, Miguel Garcia, Nadine Fournier, Etienne Meylan, Alessandra Piersigilli, Julien Robert Rémi Faget, Svenja Johanna Groeneveld, Gael Luis Boivin, Ioannis Xenarios, Inti Zlobec

AMER ASSOC CANCER RESEARCH2018

The role of Snail in non-small cell lung cancer

Svenja Johanna Groeneveld

The epithelial-to-mesenchymal transition (EMT) is a developmental program frequently reactivated in cancer. It plays an important role in several aspects of tumor progression, particularly in the acquisition of invasive capacities facilitating metastasis. ...

EPFL2018

Snail mediates repression of the Dlk1-Dio3 locus in lung tumor-infiltrating immune cells

Nadine Fournier, Etienne Meylan, Julien Robert Rémi Faget, Svenja Johanna Groeneveld

The epithelial-mesenchymal transition-inducing transcription factor Snail contributes to tumor progression in different malignancies. In the present study, we used a transcriptomics approach to elucidate the mechanism of Snail-mediated tumor growth promoti ...

2018

Neutrophils and Snail Orchestrate the Establishment of a Pro-tumor Microenvironment in Lung Cancer

Nicolas Jean Philippe Guex, Miguel Garcia, Nadine Fournier, Etienne Meylan, Loïc Steiner, Alessandra Piersigilli, Julien Robert Rémi Faget, Svenja Johanna Groeneveld, Gael Luis Boivin, Ioannis Xenarios, Inti Zlobec

Understanding the immune compartment of tumors facilitates the development of revolutionary new therapies. We used a Kras(G12D)-driven mouse model of lung cancer to establish an immune signature and identified a contribution of Gr1 + neutrophils to disease ...

Cell Press2017

GLUT3 is induced during epithelial-mesenchymal transition and promotes tumor cell proliferation in non-small cell lung cancer

Mark Jonathan Masin, Bart Deplancke, Etienne Meylan, Jessica Christine Vazquez, Natasha Ella Samson, Petra Catalina Schwalie, Svenja Johanna Groeneveld

Alterations in glucose metabolism and epithelial-mesenchymal transition (EMT) constitute two important characteristics of carcinoma progression toward invasive cancer. Despite an extensive characterization of each of them separately, the links between EMT ...

2014