Bram Trachet

Cette personne n’est plus à l’EPFL

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Publications associées (30)

Branch-related ruptures cause intramural hematoma and dissecting abdominal aortic aneurysm in angiotensin II-infused ApoE-/- mice

Nikolaos Stergiopoulos, Patrick Segers, Alessandra Piersigilli, Bram Trachet, Lydia Aslanidou

Oxford Univ Press2015

An Animal-Specific FSI Model of the Abdominal Aorta in Anesthetized Mice

Nikolaos Stergiopoulos, Patrick Segers, Bram Trachet

Recent research has revealed that angiotensin II-induced abdominal aortic aneurysm in mice can be related to medial ruptures occurring in the vicinity of abdominal side branches. Nevertheless a thorough understanding of the biomechanics near abdominal side ...

Springer2015

Vulnerable Plaque Detection and Quantification with Gold Particle-Enhanced Computed Tomography in Atherosclerotic Mouse Models

Patrick Segers, Bram Trachet

Recently, an apolipoprotein E-deficient (ApoE(-/-)) mouse model with a mutation (C1039G+/-) in the fibrillin-1 (Fbn1) gene (ApoE(-/-)Fbn1(C1039G+/-) mouse model) was developed showing vulnerable atherosclerotic plaques, prone to rupture, in contrast to the ...

B C Decker Inc2015

Dissecting abdominal aortic aneurysm in Ang II-infused mice: suprarenal branch ruptures and apparent luminal dilatation

Nikolaos Stergiopoulos, Patrick Segers, Jessica Sordet, Alessandra Piersigilli, Bram Trachet, Peter Modregger

Aims In this work, we provide novel insight into the morphology of dissecting abdominal aortic aneurysms in angiotensin II-infused mice. We demonstrate why they exhibit a large variation in shape and, unlike their human counterparts, are located suprarenal ...

Oxford University Press2015

Quantification of focal lacerations in the tunica media that cause ascending aortic aneurysm in angiotensin II-infused mice

Nikolaos Stergiopoulos, Patrick Segers, Alessandra Piersigilli, Bram Trachet, Lydia Aslanidou

Oxford Univ Press2015

Incidence, severity, mortality, and confounding factors for dissecting AAA detection in angiotensin II-infused mice: a meta-analysis

Nikolaos Stergiopoulos, Patrick Segers, Bram Trachet

Aims While angiotensin II-infused mice are the most popular model for preclinical aneurysm research, representative data on incidence, severity, and mortality of dissecting abdominal aortic aneurysms (AAAs) have never been established, and the influence of ...

Oxford University Press2015

Role of the renin-angiotensin system on abdominal aortic aneurysms

Nikolaos Stergiopoulos, Bram Trachet

BackgroundAbdominal aortic aneurysm (AAA) is a complex degenerative disease, which leads to morbidity and mortality in a large portion of the elderly population. Current treatment options for AAA are quite limited as there is no proven indication for pharm ...

Wiley-Blackwell2013

Validation of the Arteriograph working principle: questions still remain

Nikolaos Stergiopoulos, Philippe Reymond, Patrick Segers, Bram Trachet

Lippincott, Williams & Wilkins2011

Validation of the arteriograph working principle: questions still remain - reply 2

Nikolaos Stergiopoulos, Philippe Reymond, Patrick Segers, Bram Trachet

2011

Numerical validation of a new method to assess aortic pulse wave velocity from a single recording of a brachial artery waveform with an occluding cuff

Nikolaos Stergiopoulos, Philippe Reymond, Patrick Segers, Bram Trachet

Recently a new method has been proposed as a tool to measure arterial pulse wave velocity (PWV), a measure of the stiffness of the large arteries and an emerging parameter used as indicator of clinical cardiovascular risk. The method is based on measuremen ...

Springer Verlag2010

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