Publications de Karin Lederballe Meibom

Speciation-dependent molecular mechanism of electron transfer from the c-type cytochrome MtrC to U(VI)-ligand complexes

Rizlan Bernier-Latmani, Luciano Andres Abriata, Karin Lederballe Meibom, Margaux Camille Andréa Molinas

Members of the Shewanella genus transfer electrons to metal and actinide electron acceptors such as hexavalent uranium, U(VI), via c-type cytochromes. The intracellular mechanism of electron transfer is well studied but the delivery of electrons to externa ...

2025

Biosensor-aided isolation of anaerobic arsenic-methylating bacteria from soil

Rizlan Bernier-Latmani, Karin Lederballe Meibom, Hugo Sallet, Nicolas Louis Maurice Jacquemin

Microbial methylation of arsenic impacts both the toxicity and fate of this environmental contaminant, and is an important component of its biogeochemical cycle. This transformation occurs in flooded paddy fields where soil microorganisms can produce dimet ...

Oxford University Press2025

High-throughput cultivation and isolation of environmental anaerobes using selectively permeable hydrogel capsules

Rizlan Bernier-Latmani, Karin Lederballe Meibom, Hugo Sallet, Nicolas Louis Maurice Jacquemin

Over the past two decades, metagenomics has greatly expanded our understanding of microbial phylogenetic and metabolic diversity. However, most microbial taxa remain uncultured, hindering research and biotechnological applications. Isolating environmental ...

Oxford University Press (OUP)2025

Growth substrate limitation enhances anaerobic arsenic methylation by Paraclostridium bifermentans strain EML

Rizlan Bernier-Latmani, Karin Lederballe Meibom, Hugo Sallet, Jiangtao Qiao

Microbial arsenic methylation is established as a detoxification process under aerobic conditions (converting arsenite to monomethylated arsenate) but is proposed to be a microbial warfare strategy under anoxic conditions due to the toxicity of its main pr ...

American Society for Microbiology2024

BaiJ and BaiB are key enzymes in the chenodeoxycholic acid 7a-dehydroxylation pathway in the gut microbe Clostridium scindens ATCC 35704

Rizlan Bernier-Latmani, Laure Menin, Karin Lederballe Meibom, Solenne Anne Marie Marion, Théo Nass, Eduard Vico Oton, Colin Volet

Bile acid transformation is a common gut microbiome activity that produces secondary bile acids, some of which are important for human health. One such process, 7α-dehydroxylation, converts the primary bile acids, cholic acid and chenodeoxycholic acid, to ...

2024

Strain-dependent induction of primary bile acid 7-dehydroxylation by cholic acid

Rizlan Bernier-Latmani, Karin Lederballe Meibom, Nicolas Louis Maurice Jacquemin, Eduard Vico Oton, Colin Volet

Springer Science and Business Media LLC2024

Mechanism of Reduction of Aqueous U(V)-dpaea and Solid-Phase U(VI)-dpaea Complexes: The Role of Multiheme c-Type Cytochromes

Marinella Mazzanti, Rizlan Bernier-Latmani, Karin Lederballe Meibom, Radmila Faizova, Margaux Camille Andréa Molinas

The biological reduction of soluble U(VI) complexes to form immobile U(IV) species has been proposed to remediate contaminated sites. It is well established that multiheme c-type cytochromes (MHCs) are key mediators of electron transfer to aqueous phase U( ...

2023

Dataset of scientific article "Variability in Arsenic Methylation Efficiency across Aerobic and Anaerobic Microorganisms"

Rizlan Bernier-Latmani, Karen Elda Viacava Romo, Karin Lederballe Meibom, Arnaud Michel Gelb

Dataset for journal paper entitled "Variability in Arsenic Methylation Efficiency across Aerobic and Anaerobic Microorganisms" (DOI: 10.1021/acs.est.0c03908). Partial publication's abstract: "Microbially-mediated methylation of arsenic (As ...

Zenodo2023

Meta-omics-aided isolation of an elusive anaerobic arsenic-methylating soil bacterium

Rizlan Bernier-Latmani, Karen Elda Viacava Romo, Karin Lederballe Meibom, Matthew Charles Reid, Nicolas Louis Maurice Jacquemin, Jiangtao Qiao

Soil microbiomes harbor unparalleled functional and phylogenetic diversity and are sources of novel metabolisms. However, extracting isolates with a targeted function from complex microbiomes is not straightforward, particularly if the associated phenotype ...

2022

Variability in arsenic methylation efficiency across aerobic and anaerobic microorganisms

Rizlan Bernier-Latmani, Leia Soraya Véronique Falquet, Shannon Eliot Dyer, Karen Elda Viacava Romo, Karin Lederballe Meibom, Arnaud Michel Gelb, Adrien Mestrot

Microbially-mediated methylation of arsenic (As) plays an important role in the As biogeochemical cycle, particularly in rice paddy soils where methylated As, generated microbially, is translocated into rice grains. The presence of the arsenite (As(III)) m ...

2020

Impact of iron reduction on the metabolism of Clostridium acetobutylicum

Rizlan Bernier-Latmani, Vassily Hatzimanikatis, Karin Lederballe Meibom, Cornelia List, Zhaleh Hosseini

Iron is essential for most living organisms. In addition, its biogeochemical cycling influences important processes in the geosphere (e.g., the mobilization or immobilization of trace elements and contaminants). The reduction of Fe(III) to Fe(II) can be ca ...

2019

The small RNA RyhB is a regulator of cytochrome expression in Shewanella oneidensis

Rizlan Bernier-Latmani, Karin Lederballe Meibom

Shewanella oneidensis produces an extensive electron transfer network that results in metabolic flexibility. A large number of c-type cytochromes are expressed by S. oneidensis and these function as the fundamental electron transport chain proteins. Althou ...

Frontiers Media SA2018

High throughput 3D super-resolution microscopy reveals Caulobacter crescentus in vivo Z-ring organization

Suliana Manley, Thomas Pengo, Seamus John Holden, Karin Lederballe Meibom

We created a high-throughput modality of photoactivated localization microscopy (PALM) that enables automated 3D PALM imaging of hundreds of synchronized bacteria during all stages of the cell cycle. We used high-throughput PALM to investigate the nanoscal ...

National Academy of Sciences2014