Publications de Francesco Maria Petrini

Author Correction: Bringing sensation to prosthetic hands-chronic assessment of implanted thin-film electrodes in humans (vol 7, 51, 2023)

Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Ivo Strauss, Giacomo Valle

2024

Bringing sensation to prosthetic hands-chronic assessment of implanted thin-film electrodes in humans

Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Ivo Strauss, Giacomo Valle

Direct stimulation of peripheral nerves with implantable electrodes successfully provided sensory feedback to amputees while using hand prostheses. Longevity of the electrodes is key to success, which we have improved for the polyimide-based transverse int ...

2023

Corrigendum: A Psychometric Platform to Collect Somatosensory Sensations for Neuroprosthetic Use (vol 3, 619280, 2021)

Edoardo D'Anna, Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Ivo Strauss, Giacomo Valle, Francesco Iberite

2022

A Software Tool for the Real-Time in Vivo Evaluation of Neural Electrodes' Selectivity

Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Ivo Strauss, Daniela De Luca

High neural selectivity is an important indicator of how well a neural electrode will perform in a clinical setup. Among other factors, neural selectivity of an electrode strongly depends on its implant location. Today, the neural selectivity is evaluated ...

IEEE2021

A Psychometric Platform to Collect Somatosensory Sensations for Neuroprosthetic Use

Edoardo D'Anna, Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Ivo Strauss, Giacomo Valle, Francesco Iberite

2021

Brain reactions to the use of sensorized hand prosthesis in amputees

Fabrizio Vecchio, Edoardo D'Anna, Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Ivo Strauss, Giacomo Valle, Francesco Iberite

Objective We investigated for the first time the presence of chronic changes in the functional organization of sensorimotor brain areas induced by prolonged training with a bidirectional hand prosthesis. Methods A multimodal neurophysiological and neuroima ...

2020

Cortical plasticity after hand prostheses use: Is the hypothesis of deafferented cortex "invasion" always true?

Pablo Garcia del Valle, Edoardo D'Anna, Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Ivo Strauss, Giacomo Valle, Francesco Iberite

Objective: To study motor cortex plasticity after a period of training with a new prototype of bidirectional hand prosthesis in three left trans-radial amputees, correlating these changes with the modification of Phantom Limb Pain (PLP) in the same period. ...

ELSEVIER IRELAND LTD2020

Morphological Neural Computation Restores Discrimination of Naturalistic Textures in Trans-radial Amputees

Fabrizio Vecchio, Silvestro Micera, Francesco Maria Petrini, Ivo Strauss, Giacomo Valle, Roberto Puddu, Simone Romeni

Humans rely on their sense of touch to interact with the environment. Thus, restoring lost tactile sensory capabilities in amputees would advance their quality of life. In particular, texture discrimination is an important component for the interaction wit ...

Nature Research2020

Decoding of grasping tasks from intraneural recordings in trans-radial amputee

Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Ivo Strauss, Giacomo Valle

Objective. A major challenge in neuroprosthetics is the restoration of sensory-motor hand functions in upper-limb amputees. Neuroprostheses based on the direct re-connection of the peripheral nerves may be an interesting approach for re-establishing the na ...

2020

Sensitivity to temporal parameters of intraneural tactile sensory feedback

Edoardo D'Anna, Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Ivo Strauss, Giacomo Valle

Background Recent studies have shown that neural stimulation can be used to provide artificial sensory feedback to amputees eliciting sensations referred on the amputated hand. The temporal properties of the neural stimulation modulate aspects of evoked se ...

BioMed Central2020

Hand Control With Invasive Feedback Is Not Impaired by Increased Cognitive Load

Edoardo D'Anna, Silvestro Micera, Francesco Maria Petrini, Ivo Strauss, Giacomo Valle

Recent experiments have shown that neural stimulation can successfully restore sensory feedback in upper-limb amputees improving their ability to control the prosthesis. However, the potential advantages of invasive sensory feedback with respect to non-inv ...

2020

Stability of flexible thin-film metallization stimulation electrodes: analysis of explants after first-in-human study and improvement ofin vivoperformance

Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini

Objective.Micro-fabricated neural interfaces based on polyimide (PI) are achieving increasing importance in translational research. The ability to produce well-defined micro-structures with properties that include chemical inertness, mechanical flexibility ...

2020

Intraneural sensory feedback restores grip force control and motor coordination while using a prosthetic hand

Silvestro Micera, Francesco Maria Petrini, Ivo Strauss, Giacomo Valle, Francesco Iberite

Objective. Tactile afferents in the human hand provide fundamental information about hand-environment interactions, which is used by the brain to adapt the motor output to the physical properties of the object being manipulated. A hand amputation disrupts ...

2019

Six-Month Assessment of a Hand Prosthesis with Intraneural Tactile Feedback

Edoardo D'Anna, Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Ivo Strauss, Giacomo Valle

Objective Hand amputation is a highly disabling event, which significantly affects quality of life. An effective hand replacement can be achieved if the user, in addition to motor functions, is provided with the sensations that are naturally perceived whil ...

2019

Sensory feedback restoration in leg amputees improves walking speed, metabolic cost and phantom pain

Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Giacomo Valle, Federica Barberi, Dario Bortolotti

Conventional leg prostheses do not convey sensory information about motion or interaction with the ground to aboveknee amputees, thereby reducing confidence and walking speed in the users that is associated with high mental and physical fatigue(1-4). The l ...

2019

Enhancing functional abilities and cognitive integration of the lower limb prosthesis

Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Giacomo Valle, Federica Barberi, Dario Bortolotti

Lower limb amputation (LLA) destroys the sensory communication between the brain and the external world during standing and walking. Current prostheses do not restore sensory feedback to amputees, who, relying on very limited haptic information from the st ...

2019

Characterization of multi-channel intraneural stimulation in transradial amputees

Pablo Garcia del Valle, Edoardo D'Anna, Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Ivo Strauss, Giacomo Valle, Fiorenzo Artoni

Although peripheral nerve stimulation using intraneural electrodes has been shown to be an effective and reliable solution to restore sensory feedback after hand loss, there have been no reports on the characterization of multi-channel stimulation. A deepe ...

Springer Nature2019

Shared human–robot proportional control of a dexterous myoelectric prosthesis

Aude Billard, Edoardo D'Anna, Nicolas Sommer, Silvestro Micera, Emanuele Formento, Saurav Aryan, Vincent Alexandre Mendez, Francesco Maria Petrini, Fiorenzo Artoni, Katie Zhi Zhuang

Myoelectric prostheses allow users to recover lost functionality by controlling a robotic device with their remaining muscle activity. Such commercial devices can give users a high level of autonomy, but still do not approach the dexterity of the intact hu ...

2019

A closed-loop hand prosthesis with simultaneous intraneural tactile and position feedback

Edoardo D'Anna, Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Ivo Strauss, Giacomo Valle, Francesco Iberite

Current myoelectric prostheses allow transradial amputees to regain voluntary motor control of their artificial limb by exploiting residual muscle function in the forearm. However, the overreliance on visual cues resulting from a lack of sensory feedback i ...

AMER ASSOC ADVANCEMENT SCIENCE2019

Microneurography as a tool to develop decoding algorithms for peripheral neuro-controlled hand prostheses

Silvestro Micera, Stanisa Raspopovic, Marco Capogrosso, Francesco Maria Petrini, Jacopo Rigosa, Alessandra Pampaloni, Beatrice Barra

Background:The usability of dexterous hand prostheses is still hampered by the lack of natural and effective control strategies. A decoding strategy based on the process-ing of descending efferent neural signals recorded using peripheral neural interfaces ...

2019