Kaspar Rothenfusser

Cette personne n’est plus à l’EPFL

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Publications associées (5)

Dual action of L-Lactate on the activity of NR2B-containing NMDA receptors: from potentiation to neuroprotection

Pierre Marquet, Pierre Magistretti, Pascal Jourdain, Igor Allaman, Kaspar Rothenfusser

L-Lactate is a positive modulator of NMDAR-mediated signaling resulting in plasticity gene induction and memory consolidation. However, L-Lactate is also able to protect neurons against excito-toxic NMDAR activity, an indication of a mitigating action of L ...

Nature Research2018

Synergistic interaction of L-Lactate and Glycine to potentiate NMDA receptor activity: a new form of meta-potentiation?

Pierre Marquet, Pierre Magistretti, Pascal Jourdain, Igor Allaman, Kaspar Rothenfusser

Wiley2017

Quantitative phase-digital holographic microscopy: a new imaging modality to identify original cellular biomarkers of diseases

Christian Depeursinge, Pierre Marquet, Pierre Magistretti, Pascal Jourdain, Benjamin Rappaz, Kaspar Rothenfusser

Quantitative phase microscopy (QPM) has recently emerged as a powerful label-free technique in the field of living cell imaging allowing to non-invasively measure with a nanometric axial sensitivity cell structure and dynamics. Since the phase retardation ...

Spie-Int Soc Optical Engineering2016

L-Lactate protects neurons against excitotoxicity: implication of an ATP-mediated signaling cascade

Pierre Marquet, Pierre Magistretti, Pascal Jourdain, Igor Allaman, Kaspar Rothenfusser

Converging experimental data indicate a neuroprotective action of L-Lactate. Using Digital Holographic Microscopy, we observe that transient application of glutamate (100 μM; 2 min) elicits a NMDA-dependent death in 65% of mouse cortical neurons in culture ...

Nature Research2016

Astrocyte swelling in response to neural activation: role of cotransporters

Pierre Marquet, Pierre Magistretti, Pascal Jourdain, Daniel Boss, Kaspar Rothenfusser

Wiley-Blackwell2015

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