Publications de Donald Benjaman Conkey

Selective femtosecond laser ablation via two-photon fluorescence imaging through a multimode fiber

Demetri Psaltis, Christophe Moser, Damien Claude-Marie Loterie, Donald Benjaman Conkey, Marilisa Romito, Eirini Kakkava

We demonstrate the ability of a multimode fiber probe to provide two-photon fluorescence (TPF) imaging feedback that guides the femtosecond laser ablation (FLA) in biological samples for highly selective modifications. We implement the system through the p ...

OPTICAL SOC AMER2019

Wavefront shaping for ultrashort pulse delivery through optical fibers for imaging and ablation

Demetri Psaltis, Christophe Moser, Damien Claude-Marie Loterie, Nicolino Stasio, Donald Benjaman Conkey, Eirini Kakkava

We demonstrate high power ultrashort pulse delivery through a commercially available multicore fiber (MCF) and a multimode graded-index fiber (GRINF) for imaging and laser ablation. Lensless focusing and digital scanning of ultrashort pulses through the op ...

SPIE-INT SOC OPTICAL ENGINEERING2018

Three-dimensional microfabrication through a multimode optical fiber

Demetri Psaltis, Christophe Moser, Loïc Urio, Nicolino Stasio, Edgar Emilio Morales Delgado, Donald Benjaman Conkey

3D printing based on additive manufacturing is an advanced manufacturing technique that allows the fabrication of arbitrary macroscopic and microscopic objects. Many 3D printing systems require large optical elements or nozzles in proximity to the built st ...

Optical Soc Amer2017

A device and method for increased light transmission through cochlear bone by laser ablation for in situ intracochlear imaging

Demetri Psaltis, Donald Benjaman Conkey, Marilisa Romito

A method for visualizing structures inside a cochlea, comprising the steps of irradiating a cochlear bone with a first laser light to ablate portions of the cochlear bone, to form a thinned area of the cochlear bone, and imaging intracochlear structures by ...

2017

Imaging and pattern projection through multicore fibers using the memory effect

Demetri Psaltis, Christophe Moser, Nicolino Stasio, Donald Benjaman Conkey

It is possible to focus coherent light through a multicore fiber with a resolution finer than the core-to-core spacing using digital phase conjugation. In this paper we use the memory effect and show that the displacement of the focus spot can be realized ...

Spie-Int Soc Optical Engineering2017

Two-photon fluorescence imaging through multicore fiber with digital phase conjugation

Demetri Psaltis, Christophe Moser, Nicolino Stasio, Donald Benjaman Conkey

We present near diffraction limited two photon fluorescence (TPF) imaging through a lensless, multi-core fiber (MCF) endoscope utilizing digital phase conjugation. The ultra-small size of MCFs make them desirable tools for imaging deep into the body. TPF i ...

Spie-Int Soc Optical Engineering2016

Lensless two-photon imaging through a multicore fiber with coherence-gated digital phase conjugation

Demetri Psaltis, Christophe Moser, Nicolino Stasio, Edgar Emilio Morales Delgado, Donald Benjaman Conkey, Marilisa Romito

We performed near-diffraction limited two-photon fluorescence (TPF) imaging through a lensless, multicore-fiber (MCF) endoscope utilizing digital phase conjugation. The phase conjugation technique is compatible with commercially available MCFs with high co ...

SPIE Society of Photo-optical Instrumentation Engineers2016

Ultrafast laser ablation for targeted atherosclerotic plaque removal

Laurent Descloux, Demetri Psaltis, Thomas Jean Victor Marie Lanvin, Donald Benjaman Conkey

Coronary artery disease, the main cause of heart disease, develops as immune cells and lipids accumulate into plaques within the coronary arterial wall. As a plaque grows, the tissue layer (fibrous cap) separating it from the blood flow becomes thinner and ...

Spie-Int Soc Optical Engineering2015

Subsurface ablation of atherosclerotic plaque using ultrafast laser pulses

Demetri Psaltis, Thomas Jean Victor Marie Lanvin, Donald Benjaman Conkey

We perform subsurface ablation of atherosclerotic plaque using ultrafast pulses. Excised mouse aortas containing atherosclerotic plaque were ablated with ultrafast near-infrared (NIR) laser pulses. Optical coherence tomography (OCT) was used to observe the ...

Optical Soc Amer2015

Light control in a multicore fiber using the memory effect

Demetri Psaltis, Christophe Moser, Nicolino Stasio, Donald Benjaman Conkey

Endoscopic imaging through a multicore fiber (MCF) is widely used but is affected by pixelated images, which limits its resolution to a few micrometers. This is due to the spacing between the cores in the MCF, which is large enough to avoid core-to-core li ...

Optical Soc Amer2015

Catheter for sub-surface ablation in biological tissue

Demetri Psaltis, Thomas Jean Victor Marie Lanvin, Jae-Woo Choi, Donald Benjaman Conkey

The present invention concerns a subsurface laser-induced optical breakdown (LIOB) catheter including a probe assembly for providing at least one optical pulse to a subsurface target biological tissue site; and a waveguide for guiding the at least one opti ...

2015

Double-helix enhanced axial localization in STED nanoscopy

Demetri Psaltis, Andreas Vasdekis, Grégoire Pierre Jean Laporte, Donald Benjaman Conkey

Stimulated Emission Depletion (STED) microscopy enables subdiffraction resolution in the imaging plane. However, STED's lateral improvement in resolution is generally better than the enhancement in the axial direction. Here, we combine conventional STED su ...

Optical Society of America2013