Samuel Thomas Jones

Cette personne n’est plus à l’EPFL

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Publications associées (4)

Modified cyclodextrins as broad-spectrum antivirals

Daniel Ortiz Trujillo, Francesco Stellacci, Natalia Gasilova, Samuel Thomas Jones, Matej Janecek, Valeria Cagno, Matteo Gasbarri

Viral infections kill millions of people and new antivirals are needed. Nontoxic drugs that irreversibly inhibit viruses (virucidal) are postulated to be ideal. Unfortunately, all virucidal molecules described to date are cytotoxic. We recently developed n ...

AMER ASSOC ADVANCEMENT SCIENCE2020

Synthesis and Characterization of Amphiphilic Gold Nanoparticles

Francesco Stellacci, Paulo Henrique Jacob Silva, Zekiye Pelin Güven, Zhi Luo, Samuel Thomas Jones, Urszula Beata Cendrowska, Matteo Gasbarri

Gold nanoparticles covered with a mixture of 1-octanethiol (OT) and 11-mercapto-1-undecane sulfonic acid (MUS) have been extensively studied because of their interactions with cell membranes, lipid bilayers, and viruses. The hydrophilic ligands make these ...

JOURNAL OF VISUALIZED EXPERIMENTS2019

Broad-spectrum non-toxic antiviral nanoparticles with a virucidal inhibition mechanism

Francesco Stellacci, Paulo Henrique Jacob Silva, Marie Mueller, Ahmet Bekdemir, Samuel Thomas Jones, Emma-Rose Janecek, Valeria Cagno

Viral infections kill millions yearly. Available antiviral drugs are virus-specific and active against a limited panel of human pathogens. There are broad-spectrum substances that prevent the first step of virus–cell interaction by mimicking heparan sulfat ...

2018

Virucidal compounds and uses thereof

Francesco Stellacci, Samuel Thomas Jones, Samuel Jones

The invention relates to virucidal compounds, virucidal compositions comprising thereof and uses thereof in treatment of viral infections, for sterilizations and for disinfections. ...

2018

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