Publications de Daniela Maria Zöller

Characterization and prediction of clinical pathways of vulnerability to psychosis through graph signal processing

Dimitri Nestor Alice Van De Ville, Maude Schneider, Anjali Bagunu Tarun, Daniela Maria Zöller

Causal interactions between specific psychiatric symptoms could contribute to the heterogenous clinical trajectories observed in early psychopathology. Current diagnostic approaches merge clinical manifestations that co-occur across subjects and could sign ...

eLIFE SCIENCES PUBL LTD2021

Dysmaturation Observed as Altered Hippocampal Functional Connectivity at Rest Is Associated With the Emergence of Positive Psychotic Symptoms in Patients With 22q11 Deletion Syndrome

Dimitri Nestor Alice Van De Ville, Maude Schneider, Daniela Maria Zöller, Karin Bortolin, Farnaz Delavari

BACKGROUND: Hippocampal alterations are among the most replicated neuroimaging findings across the psychosis spectrum. Moreover, there is strong translational evidence that preserving the maturation of hippocampal networks in mice models prevents the progr ...

ELSEVIER SCIENCE INC2021

Long-term verbal memory deficit and associated hippocampal alterations in 22q11.2 deletion syndrome

Maude Schneider, Daniela Maria Zöller

Chromosome 22q11.2 deletion syndrome (22q11.2DS) is a genetic disease associated with an increased risk for schizophrenia and a specific cognitive profile. In this paper, we challenge the current view of spared verbal memory in 22q11.2DS by investigating v ...

2020

Positive psychotic symptoms are associated with divergent developmental trajectories of hippocampal volume during late adolescence in patients with 22q11DS

Daniela Maria Zöller

Low hippocampal volume is a consistent finding in schizophrenia and across the psychosis spectrum. However, there is a lack of studies investigating longitudinal hippocampal development and its relationship with psychotic symptoms. The 22q11.2 deletion syn ...

SPRINGERNATURE2020

Identifying neurodevelopmental anomalies of white matter microstructure associated with high risk for psychosis in 22q11.2DS

Marie Schaer, Maude Schneider, Maria Carmela Padula, Daniela Maria Zöller

Disruptions of white matter microstructure have been widely reported in schizophrenia. However, the emergence of these alterations during preclinical stages remains poorly understood. 22q11.2 Deletion Syndrome (22q11.2DS) represents a unique model to study ...

SPRINGERNATURE2020

Pituitary dysmaturation affects psychopathology and neurodevelopment in 22q11.2 Deletion Syndrome

Dimitri Nestor Alice Van De Ville, Maria del Carmen Sandi Perez, Marie Schaer, Maude Schneider, Maëlle Chambaz, Daniela Maria Zöller

Background 22q11.2 Deletion Syndrome (22q11DS) confers strongly increased genetic risk for multiple psychiatric disorders. Similarly to the general population, rates of psychiatric comorbidity suggest that common disease mechanisms are shared across dimens ...

2020

Robust Recovery of Temporal Overlap Between Network Activity Using Transient-Informed Spatio-Temporal Regression

Dimitri Nestor Alice Van De Ville, Marie Schaer, Fikret Isik Karahanoglu, Thomas William Arthur Bolton, Daniela Maria Zöller

Functional magnetic resonance imaging is a non-invasive tomographic imaging modality that has provided insights into system-level brain function. New analysis methods are emerging to study the dynamic behavior of brain activity. The innovation-driven co-ac ...

Institute of Electrical and Electronics Engineers2019

Dynamic organization of human brain function and its relevance for psychosis vulnerability

Daniela Maria Zöller

The brain is the substrate of a complex dynamic system providing a remarkably varied range of functionalities, going from simple perception to higher-level cognition. Disturbances in its complex dynamics can cause an equally vast variety of mental disorder ...

EPFL2019

Development of Structural Covariance From Childhood to Adolescence: A Longitudinal Study in 22q11.2DS

Dimitri Nestor Alice Van De Ville, Maude Schneider, Maria Carmela Padula, Daniela Maria Zöller

2018

Early Adaptive Functioning Trajectories in Preschoolers With Autism Spectrum Disorders

Daniela Maria Zöller

2018

Psychotic symptoms influence the development of anterior cingulate BOLD variability in 22q11.2 deletion syndrome

Dimitri Nestor Alice Van De Ville, Maude Schneider, Maria Carmela Padula, Daniela Maria Zöller

2018

Cortical morphology development in patients with 22q11.2 deletion syndrome at ultra-high risk of psychosis

Marie Schaer, Maude Schneider, Maria Carmela Padula, Daniela Maria Zöller

Background. Patients with 22q11.2 deletion syndrome (22q11DS) present a high risk of developing psychosis. While clinical and cognitive predictors for the conversion towards a full-blown psychotic disorder are well defined and largely used in practice, neu ...

CAMBRIDGE UNIV PRESS2018

Disentangling resting-state BOLD variability and PCC functional connectivity in 22q11.2 deletion syndrome

Dimitri Nestor Alice Van De Ville, Marie Schaer, Maria Carmela Padula, Daniela Maria Zöller

Although often ignored in fMRI studies, moment-to-moment variability of blood oxygenation level dependent (BOLD) signals reveals important information about brain function. Indeed, higher brain signal variability has been associated with better cognitive p ...

Elsevier2017