Publications de Susanne Petra Pfeifer

The population genetics of crypsis in vertebrates: recent insights from mice, hares, and lizards

Jeffrey David Jensen, Kristen Kay Irwin, Stefan Jean Laurent, Susanne Petra Pfeifer

By combining well-established population genetic theory with high-throughput sequencing data from natural populations, major strides have recently been made in understanding how, why, and when vertebrate populations evolve crypsis. Here, we focus on backgr ...

NATURE PUBLISHING GROUP2020

Linking a mutation to survival in wild mice

Jeffrey David Jensen, Matthieu Foll, Stefan Jean Laurent, Susanne Petra Pfeifer

Adaptive evolution in new or changing environments can be difficult to predict because the functional connections between genotype, phenotype, and fitness are complex. Here, we make these explicit connections by combining field and laboratory experiments i ...

American Association for the Advancement of Science2019

A genetic reconstruction of the invasion of the calanoid copepod Pseudodiaptomus inopinus across the North American Pacific Coast

Séverine Vuilleumier Varisco, Susanne Petra Pfeifer

2018

The Evolutionary History of Nebraska Deer Mice: Local Adaptation in the Face of Strong Gene Flow

Jeffrey David Jensen, Matthieu Foll, Stefan Jean Laurent, Susanne Petra Pfeifer

2018

The Demographic History of African Drosophila melanogaster

Adamantia Kapopoulou, Jeffrey David Jensen, Stefan Jean Laurent, Susanne Petra Pfeifer

As one of the most commonly utilized organisms in the study of local adaptation, an accurate characterization of the demographic history of Drosophila melanogaster remains as an important research question. This owes both to the inherent interest in charac ...

OXFORD UNIV PRESS2018

The ultimate and proximate mechanisms driving the evolution of long tails in forest deer mice

Susanne Petra Pfeifer

Understanding both the role of selection in driving phenotypic change and its underlying genetic basis remain major challenges in evolutionary biology. Here, we use modern tools to revisit a classic system of local adaptation in the North American deer mou ...

Wiley2017

The Demographic and Adaptive History of the African Green Monkey

Susanne Petra Pfeifer

Relatively little is known about the evolutionary history of the African green monkey (genus Chlorocebus) due to the lack of sampled polymorphism data fromwild populations. Yet, this characterization of genetic diversity is not only critical for a better u ...

Oxford Univ Press2017

On the Analysis of Intrahost and Interhost Viral Populations: Human Cytomegalovirus as a Case Study of Pitfalls and Expectations

Jeffrey David Jensen, Sebastian Matuszewski, Susanne Petra Pfeifer

Intrahost and interhost assessments of viral diversity are often treated as measures of separate and distinct evolutionary processes, with numerous investigations reporting seemingly incompatible results between the two. For example, in human cytomegalovir ...

American Society for Microbiology2017

Characterizing human cytomegalovirus reinfection in congenitally infected infants: an evolutionary perspective

Jeffrey David Jensen, Cornelia Pokalyuk, Kristen Kay Irwin, Susanne Petra Pfeifer

Given the strong selective pressures often faced by populations when colonizing a novel habitat, the level of variation present on which selection may act is an important indicator of adaptive potential. While often discussed in an ecological context, this ...

Wiley2017

From next-generation resequencing reads to a high-quality variant data set

Susanne Petra Pfeifer

Sequencing has revolutionized biology by permitting the analysis of genomic variation at an unprecedented resolution. High-throughput sequencing is fast and inexpensive, making it accessible for a wide range of research topics. However, the produced data c ...

Nature Publishing Group2017

The Impact of Linked Selection in Chimpanzees: A Comparative Study

Jeffrey David Jensen, Susanne Petra Pfeifer

Levels of nucleotide diversity vary greatly across the genomes of most species owing to multiple factors. These include variation in the underlying mutation rates, as well as the effects of both direct and linked selection. Fundamental to interpreting the ...

Oxford University Press (OUP)2016

The population genomics of rapid adaptation: disentangling signatures of selection and demography in white sands lizards

Jeffrey David Jensen, Nicky Louise Ormond, Stefan Jean Laurent, Susanne Petra Pfeifer

Understanding the process of adaptation during rapid environmental change remains one of the central focal points of evolutionary biology. The recently formed White Sands system of southern New Mexico offers an outstanding example of rapid adaptation, with ...

Wiley-Blackwell2016

Inferring the age of a fixed beneficial allele

Jeffrey David Jensen, Nicky Louise Ormond, Gregory Bruce Ewing, Matthieu Foll, Susanne Petra Pfeifer

Estimating the age and strength of beneficial alleles is central to understanding how adaptation proceeds in response to changing environmental conditions. Several haplotype-based estimators exist for inferring the age of segregating beneficial mutations. ...

Wiley-Blackwell2016