Marie Juliette Ségolène Pierron

Cette personne n’est plus à l’EPFL

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Publications associées (4)

Centriole elimination during Caenorhabditis elegans oogenesis initiates with loss of the central tube protein SAS-1

Pierre Gönczy, Mary-Claude Croisier-Coeytaux, Coralie Busso, Tamara Mikeladze-Dvali, Marie Juliette Ségolène Pierron, Keshav Jha, Alexander Woglar

In most metazoans, centrioles are lost during oogenesis, ensuring that the zygote is endowed with the correct number of two centrioles, which are paternally contributed. How centriole architecture is dismantled during oogenesis is not understood. Here, we ...

Wiley2023

Molecular architecture of the C. elegans centriole

Pierre Gönczy, Coralie Busso, Marie Juliette Ségolène Pierron, Fabian Zacharias Schneider, Keshav Jha, Alexander Woglar

Uncovering organizing principles of organelle assembly is a fundamental pursuit in the life sciences. Caenorhabditis elegans was key in identifying evolutionary conserved components governing assembly of the centriole organelle. However, localizing these c ...

2022

Centriole foci persist in starfish oocytes despite Polo-like kinase 1 inactivation or loss of microtubule nucleation activity

Pierre Gönczy, Marie Juliette Ségolène Pierron, Nils Kalbfuss

Centrioles must be eliminated or inactivated from the oocyte to ensure that only the two functional centrioles contributed by the sperm are present in the zygote. Such removal can occur during oogenesis, as in Drosophila, where departure of Polo kinase fro ...

2020

Aurora A depletion reveals centrosome-independent polarization mechanism in Caenorhabditis elegans

Pierre Gönczy, Coralie Busso, Lukas von Tobel, Christian Gentili, Marie Juliette Ségolène Pierron, Kerstin Klinkert Fabbri, Sarah Herrman

How living systems break symmetry in an organized manner is a fundamental question in biology. In wild-type Caenorhabditis elegans zygotes, symmetry breaking during anterior-posterior axis specification is guided by centrosomes, resulting in anterior-direc ...

2019

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