Publications de Berna Ayse Özkale Edelmann

Actuated 3D microgels for single cell mechanobiology

Christina Myra Tringides, Mahmut Selman Sakar, Ece Özelçi, Berna Ayse Özkale Edelmann

We present a new cell culture technology for large-scale mechanobiology studies capable of generating and applying optically controlled uniform compression on single cells in 3D. Mesenchymal stem cells (MSCs) are individually encapsulated inside an optical ...

ROYAL SOC CHEMISTRY2022

Actuated 3D microgels for single cell mechanobiology (vol 22, pg 1962, 2022)

Christina Myra Tringides, Mahmut Selman Sakar, Ece Özelçi, Berna Ayse Özkale Edelmann

ROYAL SOC CHEMISTRY2022

Active biomaterials for mechanobiology

Mahmut Selman Sakar, Berna Ayse Özkale Edelmann

Active biomaterials offer novel approaches to study mechanotransduction in mammalian cells. These material systems probe cellular responses by dynamically modulating their resistance to endogenous forces or applying exogenous forces on cells in a temporall ...

2020

Programmable microencapsulation for enhanced mesenchymal stem cell persistence and immunomodulation

Christina Myra Tringides, Berna Ayse Özkale Edelmann

Mesenchymal stem cell (MSC) therapies demonstrate particular promise in ameliorating diseases of immune dysregulation but are hampered by short in vivo cell persistence and inconsistencies in phenotype. Here, we demonstrate that biomaterial encapsulation i ...

National Academy of Sciences2019

Modular soft robotic microdevices for dexterous biomanipulation

Lucio Feo Pancaldi-Giubbini, Francesco Stellacci, Ahmet Bekdemir, Mahmut Selman Sakar, Raquel Filipa Penacho Parreira, Ece Özelçi, Berna Ayse Özkale Edelmann, Murat Kaynak

We present a methodology for building biologically inspired, soft microelectromechanical systems (MEMS) devices. Our strategy combines several advanced techniques including programmable colloidal self-assembly, light-harvesting with plasmonic nanotransduce ...

2019

Robotically controlled microprey to resolve initial attack modes preceding phagocytosis

Mahmut Selman Sakar, Berna Ayse Özkale Edelmann

2017

Inkjet printed superparamagnetic polymer composite hemispheres with programmed magnetic anisotropy

Jürgen Brugger, Loïc Jacot-Descombes, Victor Javier Cadarso Busto, Rosario Maurizio Gullo, Massimo Mastrangeli, Berna Ayse Özkale Edelmann, Christofer Hierold

We present the fabrication and characterization of large arrays of inkjet-printed superparamagnetic polymer composite (SPMPC) hemispherical microstructures. SPMPCs are appealing for applications in microsystems and nanorobotics due to the added functionali ...

Royal Soc Chemistry2014