Publications de Estelle Emeline Raffin

Improved Spinal Cord FMRI Activation Mapping Using Regularized Hemodynamic Deconvolution

Dimitri Nestor Alice Van De Ville, Friedhelm Christoph Hummel, Estelle Emeline Raffin, Ekansh Sareen

The spinal cord plays a central role in regulating sensorimotor functions through complex neural pathways. However, detailed investigation of these mechanisms remains a developing field. In this study, we propose a multimodal approach combining transcrania ...

IEEE2025

Pathway-dependent Brain Stimulation Responses Indicate Motion Processing Integrity After Stroke

Elena Beanato, Michele Bevilacqua, Friedhelm Christoph Hummel, Estelle Emeline Raffin, Sarah Bernardina Zandvliet, Pauline Menoud, Fabienne Windel, Lisa Aïcha Mireille Julie Fleury

Homonymous hemianopia (HH), a common visual impairment resulting from occipital lobe lesions, affects a significant number of stroke survivors. Intensive perceptual training can foster recovery, possibly by enhancing surviving visual pathways. This study e ...

OXFORD UNIV PRESS2025

Dimming chronic pain with ultrasound: hope for the future?

Estelle Emeline Raffin

LIPPINCOTT WILLIAMS & WILKINS2024

MEP and TEP features variability: is it just the brain-state?

Sylvain Jean-François Harquel, Michele Bevilacqua, Claudia Bigoni, Friedhelm Christoph Hummel, Estelle Emeline Raffin, Andéol Geoffroy Cadic-Melchior

Objective. The literature investigating the effects of alpha oscillations on corticospinal excitability is divergent. We believe inconsistency in the findings may arise, among others, from the electroencephalography (EEG) processing for brain-state determi ...

Iop Publishing Ltd2024

Single session cross-frequency bifocal tACS modulates visual motion network activity in young healthy population and stroke patients

Michele Bevilacqua, Friedhelm Christoph Hummel, Estelle Emeline Raffin, Roberto Felipe Salamanca Giron, Sarah Bernardina Zandvliet, Pauline Menoud, Fabienne Windel, Lisa Aïcha Mireille Julie Fleury

Objective: This study investigates the impact of single-session, cross-frequency (Alpha-Gamma) bifocal transcranial alternating current stimulation (cf-tACS) to the cortical visual motion network on inter-areal coupling between the primary visual cortex (V ...

2024

Low-Intensity Focused Ultrasound Neuromodulation for Stroke Recovery: A Novel Deep Brain Stimulation Approach for Neurorehabilitation?

Grégoire Courtine, Jocelyne Bloch, Friedhelm Christoph Hummel, Shiqi Sun, Estelle Emeline Raffin, Mahmut Yüksel

Stroke as the leading cause of adult long-term disability and has a significant impact on patients, society and socio-economics. Non-invasive brain stimulation (NIBS) approaches such as transcranial magnetic stimulation (TMS) or transcranial electrical sti ...

Ieee-Inst Electrical Electronics Engineers Inc2023

Pathway and directional specificity of Hebbian plasticity in the cortical visual motion processing network

Michele Bevilacqua, Friedhelm Christoph Hummel, Estelle Emeline Raffin

Cortico-cortical paired associative stimulation (ccPAS), which repeatedly pairs single-pulse transcranial magnetic stimulation (TMS) over two distant brain regions, is thought to modulate synaptic plasticity. We explored its spatial selectivity (pathway an ...

2023

Performing well but not appreciating it - A trait feature of anorexia nervosa

Estelle Emeline Raffin

BackgroundDespite advances in the etiology of anorexia nervosa (AN), a large subgroup of individuals does not profit optimally from treatment. Perfectionism has been found to be a risk factor predicting the onset, severity, and duration of AN episodes. To ...

WILEY2023

Multi-scale and cross-dimensional TMS mapping: A proof of principle in patients with Parkinson's disease and deep brain stimulation

Sylvain Jean-François Harquel, Estelle Emeline Raffin

IntroductionTranscranial magnetic stimulation (TMS) mapping has become a critical tool for exploratory studies of the human corticomotor (M1) organization. Here, we propose to gather existing cutting-edge TMS-EMG and TMS-EEG approaches into a combined mult ...

FRONTIERS MEDIA SA2023

Toward individualized medicine in stroke-The TiMeS project: Protocol of longitudinal, multi-modal, multi-domain study in stroke

Jean-Philippe Thiran, Dimitri Nestor Alice Van De Ville, Olaf Blanke, Philip Egger, Sylvain Jean-François Harquel, Silvestro Micera, Nathalie Heidi Meyer, Elena Beanato, Valérie Rita Madeleine Zufferey, Gabriel Girard, Julia Brügger, Friedhelm Christoph Hummel, Takuya Morishita, Maximilian Jonas Wessel, Philipp Johannes Koch, Estelle Emeline Raffin, Andéol Geoffroy Cadic-Melchior, Traian Popa, Pauline Menoud, Lisa Aïcha Mireille Julie Fleury

Despite recent improvements, complete motor recovery occurs in < 15% of stroke patients. To improve the therapeutic outcomes, there is a strong need to tailor treatments to each individual patient. However, there is a lack of knowledge concerning the preci ...

FRONTIERS MEDIA SA2022

Exploring the spatial resolution of TMS-EEG coupling on the sensorimotor region

Sylvain Jean-François Harquel, Estelle Emeline Raffin

The use of TMS-EEG coupling as a neuroimaging tool for the functional exploration of the human brain recently gained strong interest. If this tool directly inherits the fine temporal resolution from EEG, its spatial counterpart remains unknown. In this stu ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2022

Functional Segregation within the Dorsal Frontoparietal Network: A Multimodal Dynamic Causal Modeling Study

Estelle Emeline Raffin

Discrimination and integration of motion direction requires the interplay of multiple brain areas. Theoretical accounts of perception suggest that stimulus-related (i.e., exogenous) and decision-related (i.e., endogenous) factors affect distributed neurona ...

OXFORD UNIV PRESS INC2021

Enhancing visual motion discrimination by desynchronizing bifocal oscillatory activity

Martin Seeber, Friedhelm Christoph Hummel, Estelle Emeline Raffin, Roberto Felipe Salamanca Giron, Sarah Bernardina Zandvliet

Visual motion discrimination involves reciprocal interactions in the alpha band between the primary visual cortex (V1) and mediotemporal areas (V5/MT). We investigated whether modulating alpha phase synchronization using individualized multisite transcrani ...

2021

The various forms of sensorimotor plasticity following limb amputation and their link with rehabilitation strategies

Estelle Emeline Raffin

Limb amputation is characterized by complex and intermingled brain reorganization processes combining sensorimotor deprivation induced by the loss of the limb per se, and compensatory behaviors, such as the over-use of the intact or remaining limb. While a ...

2021

Probing regional cortical excitability via input-output properties using transcranial magnetic stimulation and electroencephalography coupling

Estelle Emeline Raffin

The modular organization of the cortex refers to subsets of highly interconnected nodes, sharing specific cytoarchitectural and dynamical properties. These properties condition the level of excitability of local pools of neurons. In this study, we describe ...

Wiley2020

Probing Context-Dependent Modulations of Ipsilateral Premotor-Motor Connectivity in Relapsing-Remitting Multiple Sclerosis

Estelle Emeline Raffin

Objective: We employed dual-site TMS to test whether ipsilateral functional premotor-motor connectivity is altered in relapsing-remitting Multiple Sclerosis (RR-MS) and is related to central fatigue. ...

FRONTIERS MEDIA SA2020

Perspectives: Hemianopia—Toward Novel Treatment Options Based on Oscillatory Activity?

Friedhelm Christoph Hummel, Estelle Emeline Raffin, Roberto Felipe Salamanca Giron

Stroke has become one of the main causes of visual impairment, with more than 15 million incidences of first-time strokes, per year, worldwide. One-third of stroke survivors exhibit visual impairment, and most of them will not fully recover. Some recovery ...

2019

Restoring Motor Functions After Stroke: Multiple Approaches and Opportunities

Friedhelm Christoph Hummel, Estelle Emeline Raffin

More than 1.5 million people suffer a stroke in Europe per year and more than 70% of stroke survivors experience limited functional recovery of their upper limb, resulting in diminished quality of life. Therefore, interventions to address upper-limb impair ...

2018

Use-Dependent Plasticity in Human Primary Motor Hand Area: Synergistic Interplay Between Training and Immobilization

Estelle Emeline Raffin

Training and immobilization are powerful drivers of use-dependent plasticity in human primary motor hand area (M1HAND). In young right-handed volunteers, corticomotor representations of the left first dorsal interosseus and abductor digiti minimi muscles w ...

2018