Publications de Patrick Daniel Barth

Reprogramming G protein coupled receptor structure and function

2018

Computational design of GPCR structure, stability and function

AMER CHEMICAL SOC2018

Enhancing Structure Prediction and Design of Soluble and Membrane Proteins with Explicit Solvent-Protein Interactions

Solvent molecules interact intimately with proteins and can profoundly regulate their structure and function. However, accurately and efficiently modeling protein solvation effects at the molecular level has been challenging. Here, we present a method that ...

2017

Evolutionary-guided de novo structure prediction of self-associated transmembrane helical proteins with near-atomic accuracy

Patrick Daniel Barth, Yi Wang

Nature Research2015