Publications de Patrick Karl Alois Neff

Advances on Real Time M/EEG Neural Feature Extraction

Nicolas Henchoz, Dimitri Nestor Alice Van De Ville, Delphine Ribes Lemay, Andreas Sonderegger, Emily Clare Groves, Patrick Karl Alois Neff

This paper introduces MNE-RT, a Python package designed for real-time neural feature extraction from magne-toencephalography (MEG) and electroencephalography (EEG) signals in Brain-Computer Interface (BCI) systems. The package incorporates efficient algori ...

IEEE2025

Designing Feedback Stimuli in Neurofeedback: Preliminary Requirements from Experts and Users

Nicolas Henchoz, Delphine Ribes Lemay, Nicolas Gninenko, Andreas Sonderegger, Emily Clare Groves, Patrick Karl Alois Neff

This study presents the first phase of a transdisciplinary research project aimed at improving the design of visual feedback stimuli in neurofeedback (NFB) applications. While current NFB research has focused extensively on signal processing and feature ex ...

IEEE2025

Auditory Phantom Perceptions (Tinnitus) and Neurofeedback Training ‘In the Wild’: A Feasibility Study on Home Treatment

Delphine Ribes Lemay, Andreas Sonderegger, Patrick Karl Alois Neff

Tinnitus (TI) is a disease of the brain with high prevalence and often severe consequences for which no causal therapy approach has been established so far. Neurofeedback Training (NFT) is considered a promising approach to treat TI based on studies applyi ...

IEEE2025

Public and Patient Involvement in Tinnitus Research

Patrick Karl Alois Neff

Public or patient involvement has only recently been established in tinnitus research. Citizen science (CS), community science, or participatory research are modes of scientific research which involve members of the general population with different levels ...

Springer International Publishing2024

Cochlear implantation in adults with acquired single-sided deafness improves cortical processing and comprehension of speech presented to the non-implanted ears: a longitudinal EEG study

Patrick Karl Alois Neff

Former studies have established that individuals with a cochlear implant (CI) for treating single-sided deafness experience improved speech processing after implantation. However, it is not clear how each ear contributes separately to improve speech percep ...

Oxford University Press (OUP)2024

The statistical analysis plan for the unification of treatments and interventions for tinnitus patients randomized clinical trial (UNITI-RCT)

Marta Martinez-Camara, Patrick Karl Alois Neff

Background Tinnitus is a leading cause of disease burden globally. Several therapeutic strategies are recommended in guidelines for the reduction of tinnitus distress; however, little is known about the potentially increased effectiveness of a combination ...

BMC2023

Functional neuroimaging options for tinnitus

Patrick Karl Alois Neff

Background: The pathophysiology behind tinnitus is still not well understood. Different imaging methods help in the understanding of the complex relationships that lead to the perception of tinnitus.Objective: Herein, different functional imaging methods t ...

SPRINGER2023

Daily Contributors of Tinnitus Loudness and Distress: An Ecological Momentary Assessment Study

Patrick Karl Alois Neff

BackgroundTinnitus is a heterogeneous condition which may be associated with moderate to severe disability, but the reasons why only a subset of individuals is burdened by the condition are not fully clear. Ecological momentary assessment (EMA) allows a be ...

FRONTIERS MEDIA SA2022

Lower glutamate and GABA levels in auditory cortex of tinnitus patients: a 2D-JPRESS MR spectroscopy study

Thorsten Kleinjung, Patrick Karl Alois Neff

We performed magnetic resonance spectroscopy (MRS) on healthy individuals with tinnitus and no hearing loss (n = 16) vs. a matched control group (n = 17) to further elucidate the role of excitatory and inhibitory neurotransmitters in tinnitus. Two-dimensio ...

Nature Research2022

Sex Differences in Comorbidity Combinations in the Swedish Population

Patrick Karl Alois Neff

High comorbidity rates, especially mental-physical comorbidity, constitute an increasing health care burden, with women and men being differentially affected. To gain an overview of comorbidity rates stratified by sex across a range of different conditions ...

MDPI2022

Negative Associations of Stress and Anxiety Levels With Cytotoxic and Regulatory Natural Killer Cell Frequency in Chronic Tinnitus

Patrick Karl Alois Neff

BackgroundDepression and anxiety are known to be associated with stress-induced changes in the immune system. Bothersome tinnitus can be related to stress and often co-occurs with depression and anxiety. This study investigates associations of psychologica ...

Frontiers Media2022