Publications associées à Scalable cascaded snap-in actuators for large-stroke displacements

A comprehensive stroke risk assessment by combining atrial computational fluid dynamics simulations and functional patient data

Stroke, a major global health concern often rooted in cardiac dynamics, demands precise risk evaluation for targeted intervention. Current risk models, like the CHA 2 DS 2 -VASc \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepa ...

Nature Portfolio2024

Preserved Corticospinal Tract Revealed by Acute Perfusion Imaging Relates to Better Outcome After Thrombectomy in Stroke

Friedhelm Christoph Hummel, Philipp Johannes Koch

BACKGROUND:The indication for mechanical thrombectomy (MT) in stroke patients with large vessel occlusion has been constantly expanded over the past years. Despite remarkable treatment effects at the group level in clinical trials, many patients remain sev ...

Lippincott Williams & Wilkins2023

Fabrication and Characterization of the Kirigami-Inspired SMA-Powered Actuator

Yves Perriard, Sean Thomas, Guilain Lionel Germain Lang, Thomas Guillaume Martinez, Marjan Ghorbani

This paper presents an innovative approach to creating Shape Memory Alloys (SMA)-based actuators that are lightweight, compact, and capable of providing large strokes. Inspired by the Kirigami structure, an SMA actuator is designed using the Ω -pattern, wh ...

2023

Prediction of post-stroke motor recovery benefits from measures of sub-acute widespread network damages

Dimitri Nestor Alice Van De Ville, Elvira Pirondini, Maria Giulia Preti, Cyprien Alban Félicien Rivier

Rivier et al. report that global measures of brain connectivity estimated by introducing virtual lesions in healthy structural connectomes significantly increase the accuracy of motor recovery prediction in stroke patients when added to focal and clinical ...

OXFORD UNIV PRESS2023

Determining patterns of post-stroke motor recovery through longitudinal multimodal MRI: A step towards patient stratification

Julia Brügger

Motivated by the need for a better understanding of post-stroke recovery and new biomarkers to improve stroke patient stratification and outcomes, this thesis investigated structure-function coupling and its role in post-stroke recovery. Furthermore, in or ...

EPFL2022

Towards patient-tailored interventions for stroke recovery: graph theoretical approaches and modeling of non-invasive brain stimulation

Giorgia Giulia Evangelista

Stroke is a disease that causes the death of precious brain cells that will never grow back and which will affect one in four humans at some point in their life. While therapies and treatments for this debilitating condition are fairly standard, their outc ...

EPFL2022

High Permittivity Siloxanes as Promising Materials for Dielectric Elastomer Transducers: From Synthesis to Application

Yauhen Sheima

The speed of change in the modern world is impressive. Within the last 50 years, many devices and technologies have significantly transformed their appearance, intrinsic characteristics and improved their performance. Computers have changed from the size o ...

EPFL2022

Clip connector device and uses thereof

Anastasios Vassilopoulos

A removable clip connection device particularly adapted to bamboo structures is disclosed, as well as assemblies formed with the same and uses thereof. The clip connection features a base (100) located at a first end (10) of the device, said base having a ...

2022

Clinical value of assessing motor performance in postacute stroke patients

Kamiar Aminian, Anisoara Ionescu, Fabien Massé

Background Rehabilitative treatment plans after stroke are based on clinical examinations of functional capacity and patient-reported outcomes. Objective information about daily life performance is usually not available, but it may improve therapy personal ...

BioMed Central2021

Predictive models for response to non-invasive brain stimulation in stroke: A critical review of opportunities and pitfalls

Philip Egger, Friedhelm Christoph Hummel, Maximilian Jonas Wessel

Background: Noninvasive brain stimulation has been successfully applied to improve stroke impairments in different behavioral domains. Yet, clinical translation is limited by heterogenous comes within and across studies. It has been proposed to develop and ...

ELSEVIER SCIENCE INC2021

Integrating regional perfusion CT information to improve prediction of infarction after stroke

Dimitri Nestor Alice Van De Ville, Elisabeth Anne Dirren, Maria Giulia Preti

Physiological evidence suggests that neighboring brain regions have similar perfusion characteristics (vascular supply, collateral blood flow). It is largely unknown whether integrating perfusion CT (pCT) information from the area surrounding a given voxel ...

SAGE PUBLICATIONS INC2020

Advanced Neurotechnologies for the Restoration of Motor Function

Silvestro Micera, Friedhelm Christoph Hummel

Stroke is one of the leading causes of long-term disability. Advanced technological solutions ("neurotechnologies'') exploiting robotic systems and electrodes that stimulate the nervous system can increase the efficacy of stroke rehabilitation. Recent stud ...

2020

Evaluating the potential of hyperpolarised [1-13C] L-lactate as a neuroprotectant metabolic biosensor for stroke

Lara Buscemi Estefanell, Mor-Miri Mishkovsky, Mario Gaetano Lepore, Jean-Noël Hyacinthe, Thanh Phong Kevin Lê

Cerebral metabolism, which can be monitored by magnetic resonance spectroscopy (MRS), changes rapidly after brain ischaemic injury. Hyperpolarisation techniques boost (13)C MRS sensitivity by several orders of magnitude, thereby enabling in vivo monitoring ...

Nature Research2020

Perspectives: Hemianopia—Toward Novel Treatment Options Based on Oscillatory Activity?

Friedhelm Christoph Hummel, Estelle Emeline Raffin, Roberto Felipe Salamanca Giron

Stroke has become one of the main causes of visual impairment, with more than 15 million incidences of first-time strokes, per year, worldwide. One-third of stroke survivors exhibit visual impairment, and most of them will not fully recover. Some recovery ...

2019

Steerable device and system

Philippe Renaud, Marc Jasper Boers, Guillaume Cédric Yves Petitpierre

A steerable device for use as e.g. a guidewire for insertion into a subject's body is disclosed. The device features a single side deflection of a bendable portion located at its distal end by application of a longitudinally-directed force either on an inn ...

2019

Wearable technology in stroke rehabilitation: towards improved diagnosis and treatment of upper-limb motor impairment

Pablo Maceira Elvira, Friedhelm Christoph Hummel, Anne-Christine Schmid, Traian Popa

Stroke is one of the main causes of long-term disability worldwide, placing a large burden on individuals and society. Rehabilitation after stroke consists of an iterative process involving assessments and specialized training, aspects often constrained by ...

BioMed Central2019

Folded-Tube Soft Pneumatic Actuators for Bending

Wyatt Marshall Felt

This article presents a model and experimental results for a new class of bending soft pneumatic actuators (SPAs) made from a single section of thin-walled flexible tubing. The actuator is formed by creasing the tubing into fin-like rectangular folds and i ...

MARY ANN LIEBERT, INC2019

The functional role of beta‐oscillations in the supplementary motor area during reaching and grasping after stroke: A question of structural damage to the corticospinal tract

Friedhelm Christoph Hummel, Maximilian Jonas Wessel

Hand motor function is often severely affected in stroke patients. Non-satisfying recovery limits reintegration into normal daily life. Understanding stroke-related network changes and identifying common principles that might underlie recovered motor funct ...

Wiley2019

Hand exoskeleton device

José del Rocio Millán Ruiz, Luca Randazzo

The invention relates to a hand exoskeleton device having a modular nature. The device is designed to be wearable, portable and light in weight, and comprises from one to ten modules each having an actuating mechanism such as a linear actuator coupled with ...

2019

Cortico-Muscular Coherence Is Reduced Acutely Post-stroke and Increases Bilaterally During Motor Recovery: A Pilot Study

José del Rocio Millán Ruiz, Serafeim Perdikis, Tiffany Corbet

Motor recovery following stroke is believed to necessitate alteration in functional connectivity between cortex and muscle. Cortico-muscular coherence has been proposed as a potential biomarker for post-stroke motor deficits, enabling a quantification of r ...

2019