Publication

Treatment and prevention of aging related-disease and/or aging by the inhibition of sphingolipids

Johan Auwerx, Pirkka-Pekka Untamo Laurila
2021
Patents

Résumé

The present invention relates to an inhibitor of sphingolipids for use in the treatment or prevention of an aging related-disease and/or aging.

Source officielle

https://infoscience.epfl.ch/entities/publication/0da25364-9ae9-4d9b-98be-c92e822cbaf3

À propos de ce résultat

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Johan Auwerx, Pirkka-Pekka Untamo Laurila
2021
Patents

Résumé

The present invention relates to an inhibitor of sphingolipids for use in the treatment or prevention of an aging related-disease and/or aging.

Source officielle

https://infoscience.epfl.ch/entities/publication/0da25364-9ae9-4d9b-98be-c92e822cbaf3

À propos de ce résultat

Concepts associés (14)

Aging brain

Aging of the brain is a process of transformation of the brain in older age, including changes all individuals experience and those of illness (including unrecognised illness). Usually this refers to humans. Since life extension is only pertinent if accompanied by health span extension, and, more importantly, by preserving brain health and cognition, finding rejuvenating approaches that act simultaneously in peripheral tissues and in brain function is a key strategy for development of rejuvenating technology.

Aging-associated diseases

An aging-associated disease (commonly termed age-related disease, ARD) is a disease that is most often seen with increasing frequency with increasing senescence. They are essentially complications of senescence, distinguished from the aging process itself because all adult animals age (with rare exceptions) but not all adult animals experience all age-associated diseases. The term does not refer to age-specific diseases, such as the childhood diseases chicken pox and measles, only diseases of the elderly.

Épuration des eaux

thumb|Station d'épuration des eaux à Aguas Corrientes, en Uruguay. L’épuration des eaux est un ensemble de techniques qui consistent à purifier l'eau soit pour réutiliser ou recycler les eaux usées dans le milieu naturel, soit pour transformer les eaux naturelles en eau potable. La fin du marque l'essor des réseaux d'égouttage et d'assainissement en France (courant hygiéniste, rénovation de Paris du baron Haussman). Il s'agit d'éloigner les eaux usées des habitations et des lieux de vie.

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Publications associées (30)

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We consider optimal regimes for algorithm-assisted human decision-making. Such regimes are decision functions of measured pre-treatment variables and, by leveraging natural treatment values, enjoy a superoptimality property whereby they are guaranteed to o ...

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Microbial genome collection of aerobic granular sludge cultivated in sequencing batch reactors using different carbon source mixtures

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Aerobic granular sludge (AGS) consists of a microbial consortium that has an important role in wastewater treatment. This study investigates AGS microorganisms cultivated in a laboratory-scale sequencing batch reactor. Metagenomic sequencing was conducted ...

Amer Soc Microbiology2024

Advancing high-throughput combinatorial aging studies of hybrid perovskite thin films via precise automated characterization methods and machine learning assisted analysis

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To optimize material stability, automated high-throughput workflows are of increasing interest. However, many of those workflows either employ synthesis techniques not suitable for large-area depositions or are carried out in ambient conditions, which limi ...

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