Publications associées à Risk and regulatory hazard-based toxicological effect indicators in life-cycle assessment (LCA)

Evaluation of tire tread particle toxicity to fish using rainbow trout cell lines

Florian Frédéric Vincent Breider, Kristin Schirmer, Benoît Jean Dominique Ferrari, Gabrielle Léger, Thibault Béranger Masset

Tire and road wear particles (TRWP) resulting from tire abrasion while driving raise concerns due to their potential contribution to aquatic toxicity. Our study aimed to assess cryogenically milled tire tread (CMTT) particle toxicity, used as a proxy for T ...

2023

Numerical simulation of the fate, transport and public health risks of enteric viruses in Lake Geneva

Chaojie Li

Lakes are a fundamental feature of nature with brilliance, profoundness and complexity. Various of physical, chemical and biological changes take place three dimensionally in deep lakes, regulated by complicated boundary conditions. To understand and predi ...

EPFL2023

A risk-risk assessment framework for solar radiation modification

Concern about the increasingly high-probability, high-impact risks posed by global warming is driving the exploration of new techniques to artificially cool the planet through an approach known as solar radiation modification (SRM). Would the world be bett ...

International Risk Governance Center2021

Assessing Subaquatic Mass Movement Hazards: an Integrated Observational and Hydrodynamic Modelling Approach

Alfred Johny Wüest, Damien Bouffard, Nathalie Dubois, Carl Love Mikael Råman Vinnå

High-resolution lake and reservoir bathymetric surveys can pinpoint locations that may experience underwater landslides (subaquatic sedimentary mass movements). These can pose a risk to underwater and shoreline infrastructure. This paper outlines an approa ...

2020

EaRL: Toolbox for Earthquake Risk and Loss Assessment of Building Assets

Dimitrios Lignos, Ahmed Mohamed Ahmed Elkady, Seong-Hoon Hwang

Infrastructure (asset) risk management is essential for a resilient environment. Several industries are concerned to improve their building asset preparedness subject to seismic hazard. To this end, the development of software tools that quantify and asses ...

2018

Engineered nanomaterials: toward effective safety management in research laboratories

Heinrich Hofmann, Thierry Meyer, Amela Groso, Alke Fink

Background: It is still unknown which types of nanomaterials and associated doses represent an actual danger to humans and environment. Meanwhile, there is consensus on applying the precautionary principle to these novel materials until more information is ...

BioMed Central2016

Investigating Alternatives To The Fish Early-Life Stage Test: A Strategy For Discovering And Annotating Adverse Outcome Pathways For Early Fish Development

Kristin Schirmer

The fish early-life stage (FELS) test (Organisation for Economic Co-operation and Development [OECD] test guideline 210) is the primary test used internationally to estimate chronic fish toxicity in support of ecological risk assessments and chemical manag ...

Wiley-Blackwell2014

Systems Toxicology Approach to Understand the Kinetics of Benzo(a)pyrene Uptake, Biotransformation, and DNA Adduct Formation in a Liver Cell Model

Kristin Schirmer

Cell-based models are important for deriving mechanistic information about stress response pathways that have evolved to protect cells from toxic insult, such as exposure to environmental pollutants. One determinant of the stress response is the amount of ...

Amer Chemical Soc2014

Dynamics and environmental risk assessment of the herbicide glyphosate and its metabolite AMPA in a small vineyard river of the Lake Geneva catchment

Luca Rossi, Pierre-Jean Copin

The use of pesticides may lead to environmental problems, such as surface water pollution, with a risk for aquatic organisms. In the present study, a typical vineyard river of western Switzerland was first monitored to measure discharged loads, identify so ...

Wiley-Blackwell2013

Expert Judgements in Risk Analysis: a Strategy to Overcome Uncertainities

Thierry Meyer, Amela Groso, David Nicolas Plüss

There is a need for a risk analysis technique specific for academic research laboratories. Since accurate accident data, normally required for quantitative risk analysis, are not available for this environment, expert judgements are often used to describe ...

2013

Concerns related to Safety Management of Engineered Nanomaterials in research environment

Thierry Meyer, Amela Groso

Since the rise of occupational safety and health research on nanomaterials a lot of progress has been made in generating health effects and exposure data. However, when detailed quantitative risk analysis is in question, more research is needed, especially ...

Iop Publishing Ltd2013

Advanced examination of historical masonry bridges for future traffic demands

Eugen Brühwiler, Alix Grandjean

The key to extending the service life of a historical masonry bridge is an accurate examination of its actual performance. This paper presents a risk-based safety approach which introduces a risk matrix illustrating the risk presented by a structure as a f ...

Brandenbourg University of Technology Cottbus2009

USEtox-the UNEP-SETAC toxicity model: recommended characterisation factors for human toxicity and freshwater ecotoxicity in life cycle impact assessment

Jérôme Payet

Background, aim and scope In 2005, a comprehensive comparison of life cycle impact assessment toxicity characterisation models was initiated by the United Nations Environment Program (UNEP)-Society for Environmental Toxicology and Chemistry (SETAC) Life Cy ...

2008

SAMARIS D13 - Report on preliminary studies for the use of HPFRCC for the rehabilitation of road infrastructure components

Emmanuel Denarié, Katrin Habel

The aims of the preliminary study reported in this document were twofold. Firstly, within the context of the application of UHPFRC for the rehabilitation of reinforced concrete structures, to identify the phenomena that require further study with respect t ...

MCS/SAMARIS2004

La négociation des risques technologiques : expertise et controverse publique dans les cas des biotechnologies et du climat

Marc Audétat

This thesis considers technological risks and their constitution as public problems. It supports that the main difference among risks is not to see between proved risks and uncertain risks, on the basis of the objective knowledge, but rather separates risk ...

EPFL2004