Publications associées à RAX and anophthalmia in humans: Evidence of brain anomalies

GA4GH: International policies and standards for data sharing across genomic research and healthcare

Jean-Pierre Hubaux, Junjun Zhang, Jamal Nasir

The Global Alliance for Genomics and Health (GA4GH) aims to accelerate biomedical advances by enabling the responsible sharing of clinical and genomic data through both harmonized data aggregation and federated approaches. The decreasing cost of genomic se ...

Elsevier2021

Comparison of gait characteristics between clinical and daily life settings in children with cerebral palsy

Kamiar Aminian, Anisoara Ionescu, Lena Carcreff, Stéphane Armand

Gait assessments in standardized settings, as part of the clinical follow-up of children with cerebral palsy (CP), may not represent gait in daily life. This study aimed at comparing gait characteristics in laboratory and real life settings on the basis of ...

Nature Research2020

Global maps of travel time to healthcare facilities

Kristina Gligoric

Access to healthcare is a requirement for human well-being that is constrained, in part, by the allocation of healthcare resources relative to the geographically dispersed human population(1-3). Quantifying access to care globally is challenging due to the ...

2020

A Computational Approach for the Design of Epidural Electrical Spinal Cord Stimulation Strategies to Enable Locomotion after Spinal Cord Injury

Emanuele Formento

Spinal cord injury (SCI) is a major cause of paralysis with currently no effective treatment. Epidural electrical stimulation (EES) of the lumbar spinal cord has been shown to restore locomotion in animal models of SCI, but has not yet reached the same lev ...

EPFL2018

Glucose Homeostasis: Regulation by Peripheral Circadian Clocks in Rodents and Humans

Frédéric Bruno Martin Gachon

Most organisms, including humans, have developed an intrinsic system of circadian oscillators, allowing the anticipation of events related to the rotation of Earth around its own axis. The mammalian circadian timing system orchestrates nearly all aspects o ...

Endocrine Soc2017

Robot-assisted gait training improves motor performances and modifies Motor Unit firing in post-stroke patients

Silvestro Micera

Background. Robotics and related technologies are realizing their promise to improve the delivery of rehabilitation therapy but the mechanism by which they enhance recovery is still unknown. The electromechanical-driven gait orthosis Lokomat has demonstrat ...

Edizioni Minerva Medica2015

Human-Specific Histone Methylation Signatures at Transcription Start Sites in Prefrontal Neurons

Jeffrey David Jensen

Cognitive abilities and disorders unique to humans are thought to result from adaptively driven changes in brain transcriptomes, but little is known about the role of cis-regulatory changes affecting transcription start sites (TSS). Here, we mapped in huma ...

Public Library Science2012