Publications associées à INJECTABLE SUPERPARAMAGNETIC NANOPARTICLES FOR TREATMENT BY HYPERTHERMIA AND USE FOR FORMING AN HYPERTHERMIC IMPLANT

Review on Uric Acid Recognition by MOFs with a Future in Machine Learning

Uric acid (UA) is produced from purine metabolism and serves as a prevalent biomarker for multiple diseases including cancer. Hyperuricemia or hypouricemia can cause multiple dysfunctions throughout the biological processes. Consequently, there is a pressi ...

Amer Chemical Soc2023

Three-dimensional buoyant hydraulic fractures: finite volume release

Andreas Möri, Brice Tanguy Alphonse Lecampion

In impermeable media, a hydraulic fracture can continue to expand even without additional fluid injection if its volume exceeds the limiting volume of a hydrostatically loaded radial fracture. This limit depends on the mechanical properties of the surround ...

Cambridge University Press2023

A plane‐strain hydraulic fracture driven by a shear‐thinning Carreau fluid

Brice Tanguy Alphonse Lecampion, Lucas Pereira

We study the propagation of a plane‐strain hydraulic fracture driven by a shear thinning fluid following a Carreau rheology. We restrict to the impermeable medium case and quantify in details the impact on fracture growth of the shear‐thinning properties o ...

2021

Geometric mixing

Nicolas Piro Mastracchio

Mixing fluids often involves a periodic action, like stirring one's tea. But reciprocating motions in fluids at low Reynolds number, in Stokes flows where inertia is negligible, lead to periodic cycles of mixing and unmixing, because the physics, molecular ...

ROYAL SOC2020

Production of monodisperse drops from viscous fluids

Esther Amstad, Mathias Steinacher, Armend Gazmeno Hati, Tomasz Radoslaw Szymborski

Drops are often used as picoliter-sized reaction vessels, for example for high-throughput screening assays, or as templates to produce particles of controlled sizes and compositions. Many of these applications require close control over the size of drops, ...

2018

PZE-transduced Suspended Microchannel Resonators for sensing applications

Annalisa De Pastina

This PhD thesis aims at developing a system which can measure the mechanical properties of fluidic samples in the picoliter range. The ultimate goal is the characterization of cancer cells and viscoelastic fluids (i.e. biological fluids), in order to study ...

EPFL2018

Transcellular Pathways in Lymphatic Endothelial Cells Regulate Changes in Solute Transport by Fluid Stress

Melody Swartz, Witold Waldemar Kilarski, Esra Güç, Marco Pisano, Valentina Triacca

Rationale: The transport of interstitial fluid and solutes into lymphatic vessels is important for maintaining interstitial homeostasis and delivering antigens and soluble factors to the lymph node for immune surveillance. Transendothelial transport across ...

Lippincott Williams & Wilkins2017

A Microfluidic Brain Interface for In Vivo Recording of Neurochemical Activity

Guillaume Cédric Yves Petitpierre

Neurological disorders have a strong negative impact on the quality of life of affected patients, their close relatives as well as on the health economic system. Early diagnosis associated with better treatment outcomes remain difficult to reach. Similarly ...

EPFL2017

Detection of Pressure or Flow Rate Variations in MR Valves through Magnetic Flux Analysis

Yves Perriard, Yoan René Cyrille Civet, Daniel Grivon

Magneto-Rheological (MR) fluids consist in a suspension of ferromagnetic particles dispersed in a fluid carrier. If excited by a magnetic source, the nearby magnetic field induces the particles magnetization with the formation of chainlike structures align ...

2016

Proteomics of Cerebrospinal Fluid: Throughput and Robustness Using a Scalable Automated Analysis Pipeline for Biomarker Discovery

Loïc Dayon, Martin Kussmann

Cerebrospinal fluid (CSF) is a body fluid of high clinical relevance and an important source of potential biomarkers for brain-associated damages, such as traumatic brain injury and stroke, and for brain diseases, such as Alzheimer's and Parkinson's. Herei ...

Amer Chemical Soc2015

ALE/finite element modeling of an unconfined bubble plume in periodic domain: bubble shape and oscillation analysis

John Richard Thome, Gustavo Rabello Dos Anjos, Gustavo Charles Peixoto de Oliveira

This paper introduces a numerical model developed based upon the arbitrary Lagrangian-Eulerian/finite element scheme to analyze bubble plumes in a periodic domain. A spherical air bubble is immersed into a large pool of quiescent water to act as an unconfi ...

Springer Heidelberg2015

Fluid mechanics of intrathecal drug delivery

Radboud Michael Nelissen

The aim of this principally experimental study is to understand from fluid mechanic principles why an insignificant anesthetic dose administered as a short bolus into the cerebrospinal fluid inside the subarachnoid space provides greater pain relief than a ...

EPFL2008

An ultra-thin PDMS membrane as a bio/micro-nano interface: fabrication and characterization

Melody Swartz

We report a method for making ultra-thin PDMS membrane devices. Freely suspended membranes as thin as 70 nm have been fabricated. Bulging tests were performed with a custom built fluidic cell to characterize large circular membranes. The fluidic cell allow ...

Springer Verlag2007

Development of a novel drug delivery system based on polymeric, thermoresponsive, hydrogel nanoparticles

Carrier-mediated drug delivery has emerged as a powerful methodology for the treatment of various pathologies. The therapeutic index of traditional and novel drugs is enhanced via the increase of specificity due to targeting of drugs to a particular tissue ...

EPFL2005