Publications associées à Population density and water balance influence the global occurrence of hepatitis E epidemics

Waterborne Virus Transport and Risk Assessment in Lake Geneva Under Climate Change

Climate changes influence lake hydrodynamics and radiation levels and thus may affect the fate and transport of waterborne pathogens in lakes. This study examines the impact of climate change on the fate, transport, and associated risks of four waterborne ...

2024

Inactivation of influenza A virus in expiratory droplets and aerosol particles and the associated physicochemical drivers

Aline Laetitia Schaub

Influenza is an infectious respiratory illness caused by influenza viruses. Every year, it causes up to one billion cases of disease worldwide. Despite its high disease burden, the transmission pathway of influenza remains subject to debate. There is incre ...

EPFL2024

Host-Pathogen Interactions Through the Genomic Lens

Zhi Ming Xu

Hosts and pathogens are involved in a long-standing evolutionary arms race characterized by successive rounds of evolution. Specifically, while hosts evolve resistance against infections, pathogens adapt to re-establish virulence. Since the signatures of t ...

EPFL2023

Inborn errors of type I interferon immunity in patients with symptomatic acute hepatitis E

Jacques Fellay

Background and Aims:The clinical spectrum of human infection by HEV ranges from asymptomatic to severe acute hepatitis. Furthermore, HEV can cause diverse neurological manifestations, especially Parsonage-Turner syndrome. Here, we used a large-scale human ...

Lippincott Williams & Wilkins2023

Using machine learning to generate an open-access cropland map from satellite images time series in the Indian Himalayan region

Danya Li

Crop maps are crucial for agricultural monitoring and food management and can additionally support domain-specific applications, such as setting cold supply chain infrastructure in developing countries. Machine learning (ML) models, combined with freely-av ...

Elsevier2023

Dynamic pulse scheduling in ASDEX Upgrade: Disruption avoidance and investigation of the H-Mode density limit

Federico Alberto Alfredo Felici, Alessandro Pau, Bernhard Sieglin

Operation of a tokamak device requires the coordinated operation of a multitude of systems. The sequence of operations during a discharge is both too complex and fast for human interaction. A common way of operation is a predefined sequence of operations w ...

2023

Numerical simulation of the fate, transport and public health risks of enteric viruses in Lake Geneva

Chaojie Li

Lakes are a fundamental feature of nature with brilliance, profoundness and complexity. Various of physical, chemical and biological changes take place three dimensionally in deep lakes, regulated by complicated boundary conditions. To understand and predi ...

EPFL2023

Ageing-aware battery discharge prediction with deep learning

Olga Fink, Luca Biggio

Electrochemical batteries are ubiquitous devices in our society. When employed in mission-critical applications, the ability to precisely predict their end-of-discharge under highly variable operating conditions is of paramount importance in order to suppo ...

ELSEVIER SCI LTD2023

Short-term dynamics of drainage density based on a combination of channel flow state surveys and water level measurements

Andrea Rinaldo, Izabela Bujak-Ozga, Jana Freiin von Freyberg

Headwater streams often experience intermittent flow. Consequently, the flowing drainage network expands and contracts and the flowing drainage density (DD) varies over time. Monitoring the DD dynamics is essential to understand the processes controlling i ...

Wiley2023

Waterborne virus transport and the associated risks in a large lake

Tamar Kohn, Timothy R. Julian, Chaojie Li, Xavier Fernandez Cassi

Waterborne enteric viruses in lakes, especially at recreational water sites, may have a negative impact on human health. However, their fate and transport in lakes are poorly understood. In this study, we propose a coupled water quality and quantitative mi ...

2022

The Rising Impacts of the COVID-19 Pandemic and the Russia-Ukraine War: Energy Transition, Climate Justice, Global Inequality, and Supply Chain Disruption

Simon Elias Bibri

This perspective paper explores the rising impacts of the COVID-19 and the Russia-Ukraine war from different perspectives, with an emphasis on the role of climate financing in achieving equitable and just transition mechanisms and that of peace in expediti ...

MDPI2022

Genomic Diversity of Torque Teno Virus in Blood Samples from Febrile Paediatric Outpatients in Tanzania: A Descriptive Cohort Study

Mary-Anne Hartley

Torque teno virus (TTV) is considered to be an ubiquitous member of the commensal human blood virome commonly reported in mixed genotype co-infections. This study investigates the genomic diversity of TTV in blood samples from 816 febrile Tanzanian childre ...

MDPI2022

Phylogenetic estimation of the viral fitness landscape of HIV-1 set-point viral load

Jacques Fellay, Luca Ferretti

Set-point viral load (SPVL), a common measure of human immunodeficiency virus (HIV)-1 virulence, is partially determined by viral genotype. Epidemiological evidence suggests that this viral property has been under stabilising selection, with a typical opti ...

OXFORD UNIV PRESS2022

A data-driven perspective on the colours of metal-organic frameworks

Luc Patiny, Seyedmohamad Moosavi, Berend Smit, Mehrdad Asgari, Christopher Patrick Ireland, Kevin Maik Jablonka

Colour is at the core of chemistry and has been fascinating humans since ancient times. It is also a key descriptor of optoelectronic properties of materials and is often used to assess the success of a synthesis. However, predicting the colour of a materi ...

2021

Past and future impacts of climate change on swiss river temperature and discharge investigated with data analysis and numerical modelling

Adrien Michel

This thesis presents the first large-scale assessment of past, present and future impacts of climate change on river temperatures in Switzerland. Water temperature is a crucial factor influencing, among others, the health of aquatic ecosystems, the industr ...

EPFL2021

Developing STEM and Team-working Skills Through Collaborative Space Robotics Missions

Francesco Mondada, Evgeniia Bonnet

Building on the success of the first North-South cross-continental collaborative educational robotics mission held in November 2015 [1], this paper presents a practical model for scaling the event up into a program for developing countries, particularly th ...

IEEE2021

Parametric study of the TF coil design for the European DEMO

Rainer Wesche, Pierluigi Bruzzone, Kamil Sedlák, Roberto Guarino

In addition to a reduced number of feeders, which would simplify their integration in the cryostat of the tokamak, the present study considers the possibility to reduce the voltage during safety discharge of the toroidal field (TF) coils. A lowered dischar ...

2021

Human mortality at extreme age

Anthony Christopher Davison, Léo Raymond-Belzile

We use a combination of extreme value statistics, survival analysis and computer-intensive methods to analyse the mortality of Italian and French semi-supercentenarians. After accounting for the effects of the sampling frame, extreme-value modelling leads ...

ROYAL SOC2021

DEA Self-discharge Characterization for Low Duty Cycle Applications

Yves Perriard, Yoan René Cyrille Civet, Raphaël Johannes Charles Mottet, Thomas Guillaume Martinez, Stefania Maria Aliki Konstantinidi

This publication presents the characterization of self discharging Dielectric Elastomer Actuators (DEAs) in order to give place to low duty cycle applications, during which a DEA must remain actuated for long periods of time. DEAs typically present a low c ...

IEEE2021

Highly Potent Host-Specific Small-Molecule Inhibitor of Paramyxovirus and Pneumovirus Replication with High Resistance Barrier

Gerardo Turcatti, Marc Chambon, Damiano Banfi, Jonathan Patrice Vesin

Multiple enveloped RNA viruses of the family Paramyxoviridae and Pneumoviridae, like measles virus (MeV), Nipah virus (NiV), canine distemper virus (CDV), or respiratory syncytial virus (RSV), are of high clinical relevance. Each year a huge number of live ...

AMER SOC MICROBIOLOGY2021