Publications associées à Synthetic Biology: A Solution for Tackling Nanomaterial Challenges

Colloidal Nanocrystals as Precursors and Intermediates in Solid State Reactions for Multinary Oxide Nanomaterials

Raffaella Buonsanti, Anna Loiudice, Valeria Mantella

Polyelemental compounds with dimensions in the nanosized regime are desirable in a large variety of applications, yet their synthesis remains a general challenge in chemistry. One of the major bottlenecks to obtaining multinary systems is the complexity of ...

2021

Viscoelastic surface electrode arrays to interface with viscoelastic tissues

Nicolas Vachicouras, Florian Dylan Fallegger, Stéphanie Lacour, Christina Myra Tringides, Alix Esther Anne Trouillet

Bioelectronic interfacing with living tissues should match the biomechanical properties of biological materials to reduce damage to the tissues. Here, the authors present a fully viscoelastic microelectrode array composed of an alginate matrix and carbon-b ...

Nature Research2021

Xeno Nucleic Acid Nanosensors for Enhanced Stability Against Ion-Induced Perturbations

Ardemis Anoush Boghossian, Justyna Kupis-Rozmyslowicz, Alice Judith Gillen, Carlo Gigli

The omnipresence of salts in biofluids creates a pervasive challenge in designing sensors suitable for in vivo applications. Fluctuations in ion concentrations have been shown to affect the sensitivity and selectivity of optical sensors based on single-wal ...

2018

Analysis of cellular and drug action mechanisms in the malaria parasites using systems biology approaches

Anush Chiappino-Pepe

Malaria puts at risk of infection half of the world population and still kills around half a million people every year. The rapid and worrisome rise of drug-resistant malaria parasites hinders the treatment of malaria and calls for a global collaboration t ...

EPFL2018

Computational methods and modeling of cellular function for the optimization of protein production and the study of cellular disease states

Joana Raquel Pinto Vieira

Systems biology is a multidisciplinary field that weaves together all the basic sciences through the use of computational and bioinformatics tools, to provide a more integrative view of the complex molecular interactions taking place within and among cells ...

EPFL2017

Carbon and Platinum Nanostructured Electrodes on Miniaturized Devices for Biomedical Diagnostics

Irene Taurino

Nowadays, medical devices face several limitations concerning rapid, reliable and simultaneous quantification of a set of ions and metabolites from a micro-nanoliter volume of undiluted samples. The development of minimally-sized devices is, therefore, of ...

EPFL2015

Carbon-based smart nanomaterials in biomedicine and neuroengineering

Michele Giugliano

The search for advanced biomimetic materials that are capable of offering a scaffold for biological tissues during regeneration or of electrically connecting artificial devices with cellular structures to restore damaged brain functions is at the forefront ...

Beilstein-Institut2014

Mathematical models and computational methods for the analysis of genome-scale protein synthesis

Julien Racle

Proteins are a ubiquitous and indispensable element for every living organism, from simple bacteria to mammals. Already in the simplest organisms, there exist some thousands of different protein species that take up a great variety of structures, and thus ...

EPFL2014

A nanoscale probe for fluidic and ionic transport

László Forró, Csilla Mikó

Surface science and molecular biology are often concerned with systems governed by fluid dynamics at the nanoscale, where different physical behaviour is expected. With advances in nanofabrication techniques, the study of fluid dynamics around a nano-objec ...

2007