Publications associées à Chemical functionalization of bio-ceramics to enhance endothelial cells adhesion for tissue engineering

Microfluidic device combining hydrodynamic and dielectrophoretic trapping for the controlled contact between single micro-sized objects and application to adhesion assays

Philippe Renaud, Arnaud Bertsch, Clémentine Sophie Sarah Lipp

The understanding of cell-cell and cell-matrix interactions via receptor and ligand binding relies on our ability to study the very first events of their contact. Of particular interest is the interaction between a T cell receptor and its cognate peptide-m ...

ROYAL SOC CHEMISTRY2023

Enhancement of Pressure-Sensitive Adhesive by CO2 Laser Treatment

Dario Floreano, Jianhang Yang, Jun Shintake, Vivek Ramachandran, Yegor Piskarev, Michael Dickey

Pressure-sensitive adhesives (PSAs) are polymeric films that can be adhered to and detached from surfaces without leaving residue. Researchers are looking to enhance the bond strength between PSAs and different substrates. It can be achieved by tuning PSA' ...

2022

Design and Development of Injectable, Tough and Intrinsically-Adhesive Hydrogels for Biomedical Applications

Peyman Karami

Despite the development of hydrogels with a wide range of mechanical properties, insufficient adhesion between these materials and biological surfaces limits their use in the biomedical applications. Most recent advancements in highly adhesive hydrogel sys ...

EPFL2021

The Mammalian Membrane Microenvironment Regulates the Sequential Attachment of Bacteria to Host Cells

Alexandre Louis André Persat, Xavier Jean-Yves Pierrat, Jeremy Pak Hei Wong

Pathogen attachment to host tissue is critical in the progress of many infections. Bacteria use adhesion in vivo to stabilize colonization and subsequently regulate the deployment of contact-dependent virulence traits. To specifically target host cells, th ...

2021

Integrin-Mediated Adhesion in the Unicellular Holozoan Capsaspora owczarzaki

Omaya Pierre Dudin

In animals, cell-matrix adhesions are essential for cell migration, tissue organization, and differentiation, which have central roles in embryonic development [1-6]. Integrins are the major cell surface adhesion receptors mediating cell-matrix adhesion in ...

CELL PRESS2020

In-flow measurement of cell-cell adhesion using oscillatory inertial microfluidics

Kevin Keim

Multicellular clusters in circulation can exhibit a substantially different function and biomarker significance compared to individual cells. Notably, clusters of circulating tumor cells (CTCs) are much more effective initiators of metastasis than single C ...

ROYAL SOC CHEMISTRY2020

Light-Activated, Bioadhesive, Poly(2-hydroxyethyl methacrylate) Brush Coatings

Dominique Pioletti, Harm-Anton Klok, Nariye Cavusoglu Ataman, Peyman Karami, Jian Wang

Rapid adhesion between tissue and synthetic materials is relevant to accelerate wound healing and to facilitate the integration of implantable medical devices. Most frequently, tissue adhesives are applied as a gel or a liquid formulation. This manuscript ...

American Chemical Society2020

Adhesion and interfacial healing between supramolecular hybrid networks and glass substrates

Véronique Michaud, Federica Sordo

Adhesion towards glass and interfacial healing of partially supramolecular hybrid polymer networks featuring a range of H-bdnds content were investigated through two dedicated adhesion test methods. In a first series of tests, adhesion strength was measure ...

Elsevier2017

Localization of adhesins on the surface of a pathogenic bacterial envelope through atomic force microscopy

Sandor Kasas, Giovanni Longo, Petar Stupar

Bacterial adhesion is the first and a significant step in establishing infection. This adhesion normally occurs in the presence of flow of fluids. Therefore, bacterial adhesins must be able to provide high strength interactions with their target surface in ...

Royal Society of Chemistry2015

ADAM17 Promotes Motility, Invasion, and Sprouting of Lymphatic Endothelial Cells

Melody Swartz, Witold Waldemar Kilarski, Renata Katarzyna Mezyk-Kopec

Tumor-associated lymphatic vessels actively participate in tumor progression and dissemination. ADAM17, a sheddase for numerous growth factors, cytokines, receptors, and cell adhesion molecules, is believed to promote tumor development, facilitating both t ...

Public Library Science2015

Cell Guidance on Nanogratings: A Computational Model of the Interplay between PC12 Growth Cones and Nanostructures

Silvestro Micera

Background: Recently, the effects of nanogratings have been investigated on PC12 with respect to cell polarity, neuronal differentiation, migration, maturation of focal adhesions and alignment of neurites. Methodology/Principal Findings: A synergistic proc ...

Public Library Science2013

An actin length threshold regulates adhesion maturation at the lamellipodium/lamellum interface

Jean-Jacques Meister, Benoît Vianay, Céline Jeanne Labouesse

The mechanical coupling between adherent cells and their substrates is a major driver of downstream behavior. This coupling relies on the formation of adhesion sites and actin bundles. How cells generate these elements remains only partly understood. A pot ...

Royal Soc Chemistry2013

Development of thermoplastic coated multifunctional transmission elements

Véronique Michaud, Basile Golaz

We report on key challenges of the development of steel cords reinforced thermoplastic elastomer composites with smart functionalities: adhesion tailoring for a durable mechanical load transfer through steel cords or other transmission elements by the use ...

Society of Photo-Optical Instrumentation Engineers (SPIE)2012

In vitro lymphatic endothelial morphogenesis : molecular vs. biophysical regulation

Carolyn Yong Pullin

Cell organization into functional multicellular three-dimensional structures is a long-standing challenge. In particular, engineering of vascularized tissues requires both blood and lymphatic neovascular network formation in a simultaneous and coordinated ...

EPFL2011

Cell-Matrix Adhesion: Slip and Immobilization under Force

Alexander Verkhovskiy

When force is applied to cell-matrix adhesion complexes, they respond by growing larger and stronger. It emerges that strengthening involves transient motion of the transmembrane integrin receptors and their eventual immobilization to the extracellular mat ...

Elsevier2010

Neuroplastin-55 binds to and signals through the fibroblast growth factor receptor

Maria del Carmen Sandi Perez

Neuroplastin (Np) is a glycoprotein belonging to the immunoglobulin superfamily of cell adhesion molecules (CAMs) and existing in two isoforms, Np55 and Np65, named according to their molecular weights. The extracellular part of Np65 contains three immunog ...

Federation of American Society of Experimental Biology2010

Dennexin peptides modeled after the homophilic binding sites of the neural cell adhesion molecule (NCAM) promote neuronal survival, modify cell adhesion and impair spatial learning

Maria del Carmen Sandi Perez, Martina Fantin

Neural cell adhesion molecule (NCAM)-mediated cell adhesion results in activation of intracellular signaling cascades that lead to cellular responses such as neurite outgrowth, neuronal survival, and modulation of synaptic activity associated with cognitiv ...

2010

Experimentation on adhesion of epoxy

Alain Curnier, Aleksandar Sekulic

In a recent article (Sekulic and Curnier (2007) [1]), an original axisymmetric epoxy-stamp on glass-disc specimen, which exhibits stable debonding, was presented for identifying the adhesive properties between epoxy and glass, namely interface debonding en ...

2010

3D collagen cultures under well-defined dynamic strain: A novel strain device with a porous elastomeric support

Melody Swartz, Alice Anna Tomei, Federica Boschetti

The field of mechanobiology has grown tremendously in the past few decades, and it is now well accepted that dynamic stresses and strains can impact cell and tissue organization, cell-cell and cell-matrix communication, matrix remodeling, cell proliferatio ...

Wiley-Blackwell2009

Adhesion failures on hard coatings induced by interface anomalies

Silviu Cosmin Sandu

In this work, the lack of adhesion occurred during the up-scaling of the deposition of tribological coatings in a semi-industrial apparatus is interpreted. The adhesion problems were detected for both hard and self-lubricant coatings from W–Ti–N and W:C sy ...

2009