Publications associées à Influence of structural dynamics on cell uptake investigated with single-chain polymeric nanoparticles

Architecturally Diverse Polymer Brushes Prepared via Surface-Initiated Atom Transfer Radical Polymerization

Polymer brushes, which are polymers anchored to a solid substrate by one chainend, have the ability to modify the properties of an underlying substrate, offering intriguing features such as enhanced lubrication, reduced friction, colloidal stability, and a ...

EPFL2023

Revealing the Formation Dynamics of Janus Polymer Particles: Insights from Experiments and Molecular Dynamics

Philip Robin Loche

Seeded emulsion polymerization is one of the best-known methods for preparing polymer particles with a controlled size, composition, and shape. It first requires the preparation of seed particles, which are then swollen with additional monomer (the same as ...

Amer Chemical Soc2023

Time Estimation of Polymer Translocation through Nano-Membrane

Maria-Alexandra Paun

In this paper, the charged polymer escapement phenomenon, via a little hole of nano-metric dimensions arranged in a constitutive biological membrane, is studied. We will present the case of the transport process of an ideal polymer in a 3-dimensional exten ...

MDPI2022

Structural characterisation of nanoalloys for (photo)catalytic applications with the Sapphire library

Kevin Rossi

A non-trivial interplay rules the relationship between the structure and the chemophysical properties of a nanoparticle. In this context, characterization experiments, molecular dynamics simulations and electronic structure calculations may allow the varia ...

ROYAL SOC CHEMISTRY2022

Static and dynamic mechanical properties of nanosilica and multiwalled carbon nanotube reinforced acrylonitrile butadiene styrene composites: theoretical mechanism of nanofiller reinforcement

Thomas Keller, Harish Mohan Thettemmel

Experimental and theoretical approaches were employed to analyze the static and dynamic mechanical properties of acrylonitrile butadiene styrene (ABS) nanocomposites reinforced with multiwalled carbon nanotube (MWCNT) and nanosilica. Enhanced stiffness and ...

SPRINGER2021

Mechanical Activation of Chemical Bonds at Polymer Interfaces

Julian Nicolas Bleich

Polymer brushes are a specific class of polymer thin films in which each chain is tethered to the underlying substrate via one chain end. In sufficiently densely grafted assemblies, the individual polymer chains are forced into an extended chain conformati ...

EPFL2021

Viscoelastic behavior of suspensions of reduced graphene oxide nanoparticles in epoxy

László Forró, Yves Leterrier, Arnaud Magrez, Maryam Majidian

The viscoelastic behavior of dilute suspensions of reduced graphene oxide (RGO) nanoparticles in a liquid SU8 epoxy dissolved in gamma butyrolactone was investigated at RGO concentrations in the range from 0.16 to 1.07 vol. %. Our results revealed that the ...

AMER INST PHYSICS2021

Born to be different: the formation process of Cu nanoparticles tunes the size trend of the activity for CO2 to CH4 conversion

Kevin Rossi, Elena Gazzarrini

We investigate the impact of the formation process of Cu nanoparticles on the distribution of adsorption sites and hence on their activity. Using molecular dynamics, we model formation pathways characteristic of physical synthesis routes as the annealing o ...

ROYAL SOC CHEMISTRY2021

Direct, Mediated, and Delayed Intramolecular Singlet Fission Mechanism in Donor-Acceptor Copolymers

Anne-Clémence Corminboeuf, Maria Fumanal Quintana

Donor-acceptor (D-A) extended copolymers have shown great potential to be exploited for intramolecular singlet fission (iSF) because of their modular tunability and intrinsic ability to incorporate low-lying charge-transfer (CT) and a triplet-pair (1TT) st ...

2020

Spatially Resolved Production of Platinum Nanoparticles in Metallosupramolecular Polymers

Emad Oveisi, Stephen Schrettl

Nanocomposites consisting of a polymer matrix and metallic nanoparticles can merge the functional, structural, and mechanical properties of the two components and are useful for applications that range from catalysis to soft electronics. Gaining spatial co ...

AMER CHEMICAL SOC2020

Phase behaviour and structure of a model biomolecular condensate

Julian Charles Shillcock

Phase separation of immiscible fluids is a common phenomenon in polymer chemistry, and is recognized as an important mechanism by which cells compartmentalize their biochemical reactions. Biomolecular condensates are condensed fluid droplets in cells that ...

2020

Efficient reductive amination of HMF with well dispersed Pd nanoparticles immobilized in a porous MOF/polymer composite

Jeremy Luterbacher, Emad Oveisi, Daniel Teav Sun, Wendy Lee Queen, Olga Trukhina, Vikram Vinayak Karve, Shuliang Yang

Aminated derivatives of 5-hydroxymethylfurfural (HMF) and furfural are critical intermediates for the pharmaceutical industry. The state-of-the-art catalysts currently used for these syntheses are mostly homogeneous in nature, motivating the design of recy ...

2020

Structural and Photophysical Templating of Conjugated Polyelectrolytes with Single-Stranded DNA

Ursula Röthlisberger, Polydefkis Diamantis, Natalie Renuka Banerji

A promising approach to influence and control the photophysical properties of conjugated polymers is directing their molecular conformation by templating. We explore here the templating effect of single-stranded DNA oligomers (ssDNAs) on cationic polythiop ...

AMER CHEMICAL SOC2020

Evolution of critical buckling conditions in imperfect bilayer shells through residual swelling

Pedro Miguel Nunes Pereira de Almeida Reis, Matteo Pezzulla, Dong Yan, Anna Lee

We propose and investigate a minimal mechanism that makes use of differential swelling to modify the critical buckling conditions of elastic bilayer shells, as measured by the knockdown factor. Our shells contain an engineered defect at the north pole and ...

ROYAL SOC CHEMISTRY2019

Controlling topology, dynamics and function of polymer brushes via post-polymerization modification

Piotr Mocny

Polymer brushes are a class of thin coatings, where each of chains is tethered to the underlying substrate via one chain end. Densely grafted polymer brushes feature a stretched chain conformation, which in a unique way enhances their lubrication and non-b ...

EPFL2019

Synthesis of Loop Poly(Methyl Methacrylate) Brushes via Chain-End Postpolymerization Modification

Harm-Anton Klok, Piotr Mocny

Polymer brushes are typically densely grafted assemblies of polymer chains that are tethered via one end group to a solid substrate. Anchoring linear polymer chains via both end groups to a surface results in loop-type polymer brushes. Although loop polyme ...

American Chemical Society2019

Cellular Uptake and Intracellular Trafficking of Poly(N-(2-Hydroxypropyl) Methacrylamide)

Harm-Anton Klok, Olivier Burri, Graham Knott, Arne Seitz, Claudia Battistella, Anders Meibom, Romain Guiet, Stéphane Laurent Escrig

Cellular uptake and intracellular trafficking of polymer conjugates or polymer nanoparticles is typically monitored using fluorescence-based techniques such as confocal microscopy. While these methods have provided a wealth of insight into the internalizat ...

American Chemical Society2019

High-Contrast Imaging of Nanodiamonds in Cells by Energy Filtered and Correlative Light-Electron Microscopy: Toward a Quantitative Nanoparticle-Cell Analysis

Theo Lasser

Fluorescent nanodiamonds (fNDs) represent an emerging class of nanomaterials offering great opportunities for ultrahigh resolution imaging, sensing and drug delivery applications. Their biocompatibility, exceptional chemical and consistent photostability r ...

2019

Sequential catalysis enables enhanced C-C coupling towards multi-carbon alkenes and alcohols in carbon dioxide reduction: a study on bifunctional Cu/Au electrocatalysts

Michael Graetzel, Shaik Mohammed Zakeeruddin, Dan Ren, Jing Gao

Electrochemical reduction of carbon dioxide (CO2) to multi-carbon products such as ethylene, ethanol and n-propanol offers a promising path for utilization of excessive CO2 and energy storage. Oxide-derived Cu electrodes are among the best electrocatalysts ...

ROYAL SOC CHEMISTRY2019

Semiaromatic Polyamides and Copolyamides Comprising Kinked Repeating Units

Julien Philippe Cretenoud

The replacement of metals with polymer-based materials is considered to be key to reducing weight, cost, and cycle times in different technological applications, including the automotive and aerospace industries. Semiaromatic polyamides are particularly at ...

EPFL2018