Publications associées à Modeling synchronization in globally coupled oscillatory systems using model order reduction

Learning the intrinsic dynamics of spatio-temporal processes through Latent Dynamics Networks

Alfio Quarteroni, Francesco Regazzoni, Stefano Pagani

Predicting the evolution of systems with spatio-temporal dynamics in response to external stimuli is essential for scientific progress. Traditional equations-based approaches leverage first principles through the numerical approximation of differential equ ...

Nature Portfolio2024

System for predicting a prognosis of the neuropsychological and/or neuropsychiatric status in a subject

Olaf Blanke, Fosco Bernasconi

The present invention relates to systems and methods for predicting a prognosis of the neuropsychological and/or neuropsychiatric status in a subject based on reports of Minor Hallucination (MH) events in combination with electrophysiological data of the s ...

2024

A Method of Moments Estimator for Interacting Particle Systems and their Mean Field Limit

Andrea Zanoni, Grigorios A. Pavliotis

We study the problem of learning unknown parameters in stochastic interacting particle systems with polynomial drift, interaction, and diffusion functions from the path of one single particle in the system. Our estimator is obtained by solving a linear sys ...

Siam Publications2024

Thouless pumping in Josephson junction arrays

Stavros Athanasiou

Recent advancements in fabrication techniques have enabled unprecedented clean interfaces and gate tunability in semiconductor-superconductor heterostructures. Inspired by these developments, we propose protocols to realize Thouless quantum pumping in elec ...

Scipost Foundation2024

Exploring High-Performance and Energy-Efficient Architectures for Edge AI-Enabled Applications

Joshua Alexander Harrison Klein

The desire and ability to place AI-enabled applications on the edge has grown significantly in recent years. However, the compute-, area-, and power-constrained nature of edge devices are stressed by the needs of the AI-enabled applications, due to a gener ...

EPFL2024

High-Resolution Modeling Without Computation Slowdown for PETALE in CROCUS

Andreas Pautz, Vincent Pierre Lamirand, Thomas Jean-François Ligonnet, Axel Guy Marie Laureau

In a collaboration between Ecole Polytechnique Fédérale de Lausanne (EPFL) and CEA, in the fall of 2020, the experimental Programme d’Étude en Transmission de l’Acier Lourd et ses Eléments (PETALE) was successfully carried out in the CROCUS reactor of EPFL ...

2024

Statistical physics of periodic biological processes

Lorenzo Talamanca

Earth rotation around its axis imposes a 24-hour rhythmicity to all life on the planet. Rather than passively responding to these periodic changes, nature has given us an internal timekeeper, the circadian clock, to anticipate to our advantage the fluctuat ...

EPFL2023

The circadian clock time tunes axonal regeneration

Thomas Haynes Hutson

Nerve injuries cause permanent neurological disability due to limited axonal regeneration. Injury-dependent and-independent mechanisms have provided important insight into neuronal regeneration, however, common denominators underpinning regeneration remain ...

Cell Press2023

Sex-dimorphic and age-dependent organization of 24-hour gene expression rhythms in humans

Felix Naef, Cédric Gobet, Lorenzo Talamanca

The circadian clock modulates human physiology. However, the organization of tissue-specific gene expression rhythms and how these depend on age and sex is not defined in humans. We combined data from the Genotype-Tissue Expression (GTEx) project with an a ...

American Association for the Advancement of Science2023

Uncovering personalized glucose responses and circadian rhythms from multiple wearable biosensors with Bayesian dynamical modeling

Felix Naef, Nicholas Edward Phillips

Wearable biosensors and smartphone applications can measure physiological variables over multiple days in free-living conditions. We measure food and drink ingestion, glucose dynamics, physical activity, heart rate (HR), and heart rate variability (HRV) in ...

CELL PRESS2023

Mice with humanized livers reveal the role of hepatocyte clocks in rhythmic behavior

Cédric Gobet, Sylviane Métairon, Frédéric Bruno Martin Gachon, Benjamin Dieter Weger

The synchronization of circadian clock depends on a central pacemaker located in the suprachiasmatic nuclei. However, the potential feedback of peripheral signals on the central clock remains poorly characterized. To explore whether peripheral organ circad ...

AMER ASSOC ADVANCEMENT SCIENCE2023

Reduced order models for coupled systems

Niccolo' Discacciati

Efficient numerical simulations of coupled multi-component systems can be particularly challenging. This is mostly due to the complexity of their solutions, as mutual interactions may cause emergent behaviors, including synchronization and instabilities. V ...

EPFL2023

How Words Move Hearts: Interpretable Machine Learning Models of Bias, Engagement, and Influence in Socio-Political Systems

Aswin Suresh

We study socio-political systems in representative democracies. Motivated by problems that affect the proper functioning of the system, we build computational methods to answer research questions regarding the phenomena occurring in them. For each phenomen ...

EPFL2023

Tumescense monitoring system for diagnosing erectile dysfunction and methods of use

Nikolaos Stergiopoulos, Rodrigo Araujo Fraga Da Silva

Systems and methods for monitoring penile tumescence are provided that overcome the drawbacks of previously known systems by providing a wearable formed of a flexible and elastic tube having a plurality of sensors disposed on or embedded within it, the wea ...

2023

Optimized office lighting advances melatonin phase and peripheral heat loss prior bedtime

Jean-Louis Scartezzini, Mirjam Münch, Lenka Maierova, Marta Benedetti

Improving indoor lighting conditions at the workplace has the potential to support proper circadian entrainment of hormonal rhythms, sleep, and well-being. We tested the effects of optimized dynamic daylight and electric lighting on circadian phase of mela ...

Nature Research2022

A simulation tool for building and lighting design considering ipRGC-influenced light responses

Marilyne Andersen, Clotilde Marie A Pierson, Myrta Gkaintatzi-Masouti

The ipRGCs in the human eye mediate several effects on people, such as alertness and circadian rhythms. The spectral, temporal and spatial characteristics of light influence the magnitude of these effects. To facilitate the anticipation of the ipRGC-influe ...

2022

Preliminary evidence that daily light exposure enhances the antibody response to influenza vaccination in patients with dementia

Jean-Louis Scartezzini

Enhancing lighting conditions in institutions for individuals with dementia improves their sleep, circadian rhythms and well-being. Here, we report first findings that exposure to brighter light during daytime may support the immune response to the annual ...

ELSEVIER2022

Type 2 diabetes disrupts circadian orchestration of lipid metabolism and membrane fluidity in human pancreatic islets

Howard Riezman, Jonathan Paz Montoya

Recent evidence suggests that circadian clocks ensure temporal orchestration of lipid homeostasis and play a role in pathophysiology of metabolic diseases in humans, including type 2 diabetes (T2D). Nevertheless, circadian regulation of lipid metabolism in ...

PUBLIC LIBRARY SCIENCE2022

Engineering and characterizing nonclassical states of light in quantum optical networks

Kilian Robert Seibold

The exploration of open quantum many-body systems -systems of microscopic size exhibiting quantum coherence and interacting with their surrounding- has emerged as a key research area over the last years. The recent advances in controlling and preserving qu ...

EPFL2022

Code Generation Approach Supporting Complex System Modeling based on Graph Pattern Matching

Dimitrios Kyritsis, Yan Yan, Jinzhi Lu

Code generation is an effective way to drive the complex system development in model-based systems engineering. Currently, different code generators are developed for different modeling languages to deal with the development of systems with multi-domain. T ...

ELSEVIER2022