Publications associées à Subcellular Chemical Imaging: New Avenues in Cell Biology

Quantified interface chemistry and biophysics via water imaging

High throughput wide-field second harmonic imaging enables the label-free imaging of interfacial (< 3 nm thick) water, with a spatial resolution of similar to 370 nm using similar to 100 ms acquisition times per image. The obtained interfacial orientationa ...

Spie-Int Soc Optical Engineering2024

Live-cell imaging powered by computation

Suliana Manley, Florian Jug

The proliferation of microscopy methods for live-cell imaging offers many new possibilities for users but can also be challenging to navigate. The prevailing challenge in live-cell fluorescence microscopy is capturing intra-cellular dynamics while preservi ...

Nature Portfolio2024

Comparing various AI approaches to traditional quantitative assessment of the myocardial perfusion in [82Rb] PET for MACE prediction

Adrien Raphaël Depeursinge, Julien René Pierre Fageot, Daniel Abler

Assessing the individual risk of Major Adverse Cardiac Events (MACE) is of major importance as cardiovascular diseases remain the leading cause of death worldwide. Quantitative Myocardial Perfusion Imaging (MPI) parameters such as stress Myocardial Blood F ...

Nature Portfolio2024

Morphological and Material Programability of a Hall-Effect Based Soft Tactile Sensors

Josephine Anna Eleanor Hughes, Sudong Lee

The different receptors in human skin show not only diversity in the stimuli to which they respond, but also variable sensitivity and directionality. This is often determined by their location or morphology, and can play an important role in filtering or a ...

IEEE2024

Functional neuroimaging options for tinnitus

Patrick Karl Alois Neff

Background: The pathophysiology behind tinnitus is still not well understood. Different imaging methods help in the understanding of the complex relationships that lead to the perception of tinnitus.Objective: Herein, different functional imaging methods t ...

SPRINGER2023

Time-resolved imaging with SPAD detectors

Jiuxuan Zhao

With the capabilities such as single-photon detection, time stamping and high-speed acquisition, time-resolved imaging based on single-photon avalanche diode (SPAD) detectors has found significant applications across diverse domains, including but not limi ...

EPFL2023

Imaging system with silicon photomultipliers and method for operating thereof

Edoardo Charbon, Andrada Alexandra Muntean

The invention relates to an integrated imaging system comprising: - an array of analog photomultiplier elements - a plurality of submodules, each submodule having a number of the photomultiplier elements; - a plurality of time-to-digital converters each as ...

2023

Porphyrin metalla-assemblies coupled to cellulose nanocrystals for PDT and imaging applications

Georges Wagnières

Photodynamic therapy (PDT) is an interesting and promising approach to tackle a broad spectrum of cancer. With the combination of a photosensitizer, light and oxygen, PDT achieves a unique selectivity by the production of localized reactive oxygen species ...

WORLD SCIENTIFIC PUBL CO PTE LTD2023

Practical computational imaging by use of spatiotemporal light modulation: from simulations to applications in biological microscopy

François Thierry M Marelli

Optical microscopy is an essential tool for biologists, who are often faced with the need to overcome the spatial and temporal resolution limitations of their devices to capture finer details. As upgrading imaging hardware is expensive, computational metho ...

EPFL2023

Amorphous Silicon Based Microchannel Plates for Time-of-Flight Positron Emission Tomography

Samira Alexandra Frey

Microchannel plates fabricated from hydrogenated amorphous silicon (AMCPs) are a promising alternative to conventional lead glass microchannel plates. Their main advantages lie in their cheaper and more flexible fabrication processes, allowing for adaptabl ...

EPFL2023

MALTA-Cz: a radiation hard full-size monolithic CMOS sensor with small electrodes on high-resistivity Czochralski substrate

Edoardo Charbon, Ashish Sharma, Francesco Piro

Depleted Monolithic Active Pixel Sensor (DMAPS) sensors developed in the Tower Semiconductor 180 nm CMOS imaging process have been designed in the context of the ATLAS ITk upgrade Phase-II at the HL-LHC and for future collider experiments. The "MALTA-Czoch ...

Iop Publishing Ltd2023

Pixel super-resolution with spatially entangled photons

Edoardo Charbon, Jiuxuan Zhao

Pixelation is common in quantum imaging systems and limit the image spatial resolution. Here, the authors introduce a pixel super-resolution approach based on measuring the full spatially-resolved joint probability distribution of spatially-entangled photo ...

Nature Portfolio2022

Medipix4, a high granularity four sides buttable pixel readout chip for high resolution spectroscopic X-ray imaging at rates compatible with medical CT scans

Viros Sriskaran

Medipix4 is the latest member in the Medipix/Timepix family of pixel detector chips aimed at high rate spectroscopic X-ray imaging using high-Z materials. The chip address the limitations of conventional hybrid pixel detectors for X-ray imaging. Its predec ...

EPFL2022

Status of the K-EUSO Orbital Detector of Ultra-High Energy Cosmic Rays

Andrii Neronov

K-EUSO (KLYPVE-EUSO) is a planned orbital mission aimed at studying ultra-high energy cosmic rays (UHECRs) by detecting fluorescence and Cherenkov light emitted by extensive air showers in the nocturnal atmosphere of Earth in the ultraviolet (UV) range. Th ...

MDPI2022

On combining denoising with learning-based image decoding

Touradj Ebrahimi, Michela Testolina

Noise is an intrinsic part of any sensor and is present, in various degrees, in any content that has been captured in real life environments. In imaging applications, several pre- and post-processing solutions have been proposed to cope with noise in captu ...

SPIE2022

Decoding the Mechanisms of Phase Transitions from In Situ Microscopy Observations

Vasiliki Tileli, Reinis Ignatans

Analysis of the temperature- and stimulus-dependent imaging data toward elucidation of the physical transformations is an ubiquitous problem in multiple fields. Here, temperature-induced phase transition in BaTiO3 is explored using the machine learning ana ...

WILEY-V C H VERLAG GMBH2022

High-Resolution Multi-Spectral Imaging With Diffractive Lenses and Learned Reconstruction

Oguzhan Fatih Kar, Can Deniz Bezek

Spectral imaging is a fundamental diagnostic technique with widespread application. Conventional spectral imaging approaches have intrinsic limitations on spatial and spectral resolutions due to the physical components they rely on. To overcome these physi ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2021

Direct time-of-flight SPAD image sensors for light detection and ranging

Preethi Padmanabhan

Depth sensing is an increasingly important feature in many applications of consumer, automotive, augmented/virtual reality (AR-VR), space and bio-medical imaging. Long range, high depth resolution, high spatial resolution, and high frame rates are often co ...

EPFL2021

Ultrasound Imaging: From Physical Modeling to Deep Learning

Dimitris Perdios

Among the medical imaging modalities, ultrasound (US) imaging is one of the safest, most widespread, and least expensive method used in medical diagnosis. In the past decades, several technological advances enabled the advent of ultrafast US imaging, an ac ...

EPFL2021

Towards quantum 3D imaging devices

Claudio Bruschini, Edoardo Charbon, Samuel Burri, Arin Can Ülkü, Paul Mos, Michael Alan Wayne

We introduce a new generation of 3D imaging devices based on quantum plenoptic imaging. Position-momentum entanglement and photon number correlations are exploited to provide a scan-free 3D image after post-processing of the collected light intensity signa ...

2021