Publications associées à When does a volume of a bundle achieve saturation? A microstructure informed tractography study

Differential Impact of Brain Network Efficiency on Poststroke Motor and Attentional Deficits

Dimitri Nestor Alice Van De Ville, Philip Egger, Nathalie Heidi Meyer, Elena Beanato, Gabriel Girard, Julia Brügger, Friedhelm Christoph Hummel, Takuya Morishita, Maximilian Jonas Wessel, Philipp Johannes Koch, Giorgia Giulia Evangelista, Andéol Geoffroy Cadic-Melchior, Lisa Aïcha Mireille Julie Fleury

Background:Most studies on stroke have been designed to examine one deficit in isolation; yet, survivors often have multiple deficits in different domains. While the mechanisms underlying multiple-domain deficits remain poorly understood, network-theoretic ...

2023

Brain connectome correlates of short-term motor learning in healthy older subjects

Manon Chloé Durand-Ruel, Friedhelm Christoph Hummel, Takuya Morishita, Maeva Moyne, Chang-Hyun Park

The motor learning process entails plastic changes in the brain, especially in brain network reconfigurations. In the current study, we sought to characterize motor learning by determining changes in the coupling behaviour between the brain functional and ...

Elsevier Masson, Corp Off2023

Axial and radial axonal diffusivities and radii from single encoding strongly diffusion-weighted MRI

Erick Jorge Canales Rodriguez, Marco Pizzolato, Tim Bjørn Dyrby

We enable the estimation of the per-axon axial diffusivity from single encoding, strongly diffusion-weighted, pulsed gradient spin echo data. Additionally, we improve the estimation of the per-axon radial diffusivity compared to estimates based on spherica ...

ELSEVIER2023

Diff3DHPE: A Diffusion Model for 3D Human Pose Estimation

Tong Zhang

Accurately estimating 3D human pose (3D HPE) and joint locations using only 2D keypoints is challenging. The noise in the predictions produced by conventional 2D human pose estimators often impeded the accuracy. In this paper, we present a diffusion-based ...

Ieee Computer Soc2023

A multi-scale probabilistic atlas of the human connectome

Meritxell Bach Cuadra, Patric Hagmann, Elena Najdenovska, Alessandra Griffa, Maxime Descoteaux

The human brain is a complex system that can be efficiently represented as a network of structural connectivity. Many imaging studies would benefit from such network information, which is not always available. In this work, we present a whole-brain multi-s ...

NATURE PORTFOLIO2022

Mapping of Structure-Function Age-Related Connectivity Changes on Cognition Using Multimodal MRI

Dimitri Nestor Alice Van De Ville, Maria Giulia Preti

The relationship between age-related changes in brain structural connectivity (SC) and functional connectivity (FC) with cognition is not well understood. Furthermore, it is not clear whether cognition is represented via a similar spatial pattern of FC and ...

FRONTIERS MEDIA SA2022

The structural connectome and motor recovery after stroke: predicting natural recovery

Jean-Philippe Thiran, Philip Egger, Elena Beanato, Gabriel Girard, Friedhelm Christoph Hummel, Takuya Morishita, Maximilian Jonas Wessel, Philipp Johannes Koch, Giorgia Giulia Evangelista, Chang-Hyun Park

Stroke patients vary considerably in terms of outcomes: some patients present ‘natural’ recovery proportional to their initial impairment (fitters), while others do not (non-fitters). Thus, a key challenge in stroke rehabilitation is to identify individual ...

2021

Validating atlas-based lesion disconnectomics in multiple sclerosis: A retrospective multi-centric study

Jonas Richiardi, Reto Meuli, Bénédicte Marie Maréchal, Tobias Kober, Mario Joao Fartaria de Oliveira

The translational potential of MR-based connectivity modelling is limited by the need for advanced diffusion imaging, which is not part of clinical protocols for many diseases. In addition, where diffusion data is available, brain connectivity analyses rel ...

2021

Bundle-Specific Axon Diameter Index as a New Contrast to Differentiate White Matter Tracts

Jean-Philippe Thiran, Giorgio Innocenti, David Paul Roger Romascano, Cristina Granziera, Alessandro Daducci, Muhamed Barakovic, Gabriel Girard, Maxime Descoteaux

In the central nervous system of primates, several pathways are characterized by different spectra of axon diameters. In vivo methods, based on diffusion-weighted magnetic resonance imaging, can provide axon diameter index estimates non-invasively. However ...

2021

Cortical Surfaces Integration with Tractography for Structural Connectivity Analysis

Gabriel Girard, Maxime Descoteaux

Background: Mapping diffusion MRI tractography streamlines to the cortical surface facilitates the integration of white matter features onto gray matter, especially for connectivity analysis. ...

MARY ANN LIEBERT, INC2021

A Signal Peak Separation Index for axisymmetric B-tensor encoding

Jean-Philippe Thiran, Benoît Macq, Gabriel Girard, Gaëtan Olivier D Rensonnet, Jonathan Rafael Patino Lopez, Marco Pizzolato

Diffusion-weighted MRI (DW-MRI) has recently seen a rising interest in planar, spherical and general B-tensor encodings. Some of these sequences have aided traditional linear encoding in the estimation of white matter microstructural features, generally by ...

Springer2021

Intra- and inter-hemispheric structural connectome in agenesis of the corpus callosum

Dimitri Nestor Alice Van De Ville, Lorena Gonçalves de Alcântara e Freitas Krikler, Vanessa Siffredi, Minghui Shi

Agenesis of the corpus callosum (AgCC) is a congenital brain malformation characterized by the complete or partial failure to develop the corpus callosum. Despite missing the largest white matter bundle connecting the left and right hemispheres of the brai ...

2021

On the cortical connectivity in the macaque brain: A comparison of diffusion tractography and histological tracing data

Jean-Philippe Thiran, Giorgio Innocenti, Gabriel Girard, Maxime Descoteaux, Tim Bjørn Dyrby

Diffusion-weighted magnetic resonance imaging (DW-MRI) tractography is a non-invasive tool to probe neural connections and the structure of the white matter. It has been applied successfully in studies of neurological disorders and normal connectivity. Rec ...

2020

Dynamic spatiotemporal patterns of brain connectivity reorganize across development

Patric Hagmann, Marie Schaer, Alessandra Griffa, Emeline Mullier

Late human development is characterized by the maturation of high-level functional processes, which rely on reshaping of white matter connections, as well as synaptic density. However, the relationship between the whole-brain dynamics and the underlying wh ...

MIT PRESS2020

DWI Simulation-Assisted Machine Learning Models for Microstructure Estimation

Jean-Philippe Thiran, Muhamed Barakovic, Gabriel Girard, Jonathan Rafael Patino Lopez, Erick Jorge Canales Rodriguez, Marco Pizzolato, Thomas Yu

Diffusion MRI (DW-MRI) allows for the detailed exploration of the brain white matter microstructure, with applications in both research and the clinic. However, state-of-the-art methods for microstructure estimation suffer from known limitations, such as t ...

Springer Nature2020

Exploring dynamic functional connectivity by incorporating prior knowledge of brain structure

Anjali Bagunu Tarun

The synchronized firing of distant neuronal populations gives rise to a wide array of functional brain networks that underlie human brain function. Given the enormous perception, learning, and cognition potential of the human brain, it is not surprising th ...

EPFL2020

Human Cochlear Nucleus on 7 Tesla Diffusion Tensor Imaging: Insights Into Micro-anatomy and Function for Auditory Brainstem Implant Surgery

Nicolas Vachicouras

Objective:The cochlear nucleus (CN) is the target of the auditory brainstem implant (ABI). Most ABI candidates have Neurofibromatosis Type 2 (NF2) and distorted brainstem anatomy from bilateral vestibular schwannomas. The CN is difficult to characterize as ...

LIPPINCOTT WILLIAMS & WILKINS2020

Sleep disturbance-related depressive symptom and brain volume reduction in shift-working nurses

Chang-Hyun Park

Disturbed sleep is the most common effect of shift work. A large corpus of research indicates an association between sleep disturbance and depressive symptom in shift workers. In this study, we proposed the mediating role of grey matter (GM) structure in t ...

Nature Research2020

On the intrahemispheric connectivity of the monkey: a diffusion tractography and tract tracing analysis

Giorgio Innocenti, Gabriel Girard, Maxime Descoteaux

In this work, we compare diffusion tractography with neuronal retrograde tract tracing of the frontal, cingulate and parietal areas of the monkey. In this work, we compare diffusion tractography with neuronal retrograde tract tracing of the frontal, cingul ...

International Society for Magnetic Resonance in Medicine2019

Towards quantitative brain connectomics: microstructure informed tractography via convex optimization

Muhamed Barakovic

Tractography is the only non-invasive technique which is used to reconstruct the white mat- ter structural connectivity of the human brain. It relies on a specific Magnetic Resonance Imaging (MRI) acquisition, called diffusion MRI, which is sensitive to th ...

EPFL2019