Publications associées à Versatile spectral modulation of a broadband source for digital holographic microscopy

In situ monitoring of femtosecond laser-induced modifications in dielectrics

Over the last decades, the progress made in the generation of laser pulses shorter than a picosecond (10^-12 s) has allowed us to reach extreme optical power intensities exceeding 10^15 W cm^-2. This tremendous power has triggered an abundance of original ...

EPFL2023

Automated Dual-Mode Cell Monitoring To Simultaneously Explore Calcium Dynamics and Contraction-Relaxation Kinetics within Drug-Treated Stem Cell-Derived Cardiomyocytes

Gerardo Turcatti, Pierre Marquet, Benjamin Rappaz, Bokyoung Kim

This manuscript proposes a new dual-mode cell imaging system for studying the relationships between calcium dynamics and the contractility process of cardiomyocytes derived from human-induced pluripotent stem cells. Practically, this dual-mode cell imaging ...

AMER CHEMICAL SOC2023

Single-shot Kramers-Kronig complex orbital angular momentum spectrum retrieval

Camille Sophie Brès, Jianqi Hu, Yujie Chen

Orbital angular momentum (OAM) spectrum diagnosis is a fundamental building block for diverse OAM-based systems. Among others, the simple on-axis interferometric measurement can retrieve the amplitude and phase information of complex OAM spectra in a few s ...

SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS2023

Towards near-atomic resolution imaging of microsecond nanoscale dynamics

Gabriele Bongiovanni

Time-resolved electron microscopy has made significant progress in recent years, with some groups now working on instruments that offer attosecond temporal resolution. While much of the research in the field revolves around the improvement of temporal reso ...

EPFL2023

High sensitivity, incoherent differential imaging

Chiara Bonati

Microscopic visualisation of optically transparent samples has been a topic of interest for several decades. Features such as density or chemical composition can influence the optical phase of transmitted light, and phase contrast can reveal these structur ...

EPFL2022

Advanced Techniques in Optical Diffraction Tomography

Ahmed Bassam Sayed Ayoub Mohamed Emam

In this thesis, we study the 3 challenges described above. First, we study different reconstruction techniques and assess the fidelity of each reconstruction results by means of structured illumination and phase conjugation. By reconstructing the 3D refrac ...

EPFL2022

Phase Reconstruction of Low-Energy Electron Holograms of Individual Proteins

Klaus Kern, Stephan Rauschenbach, Sven Alexander Szilagyi, Hannah Julia Ochner

Low-energy electron holography (LEEH) is one of the few techniques capable of imaging large and complex three-dimensional molecules, such as proteins, on the single molecule level at subnanometer resolution. During the imaging process, the structural infor ...

AMER CHEMICAL SOC2022

Tunability of space-time wave packet carrying tunable and dynamically changing OAM value

Tobias Kippenberg, Hao Song, Maxim Karpov, Xinzhou Su

Space-time (ST) wave packets have gained much interest due to their dynamic optical properties. Such wave packets can be generated by synthesizing frequency comb lines, each having multiple complex-weighted spatial modes, to carry dynamically changing orbi ...

Optica Publishing Group2022

Ultrashort Pulse Excited Tip-Enhanced Raman Spectroscopy in Molecules

Klaus Kern, Yang Luo

Vibrational fingerprints of molecules and lowdimension materials can be traced with subnanometer resolution by performing Tip-enhanced Raman spectroscopy (TERS) in a localization of light in the plasmonic nanocavity of the STM enables high spatial resoluti ...

AMER CHEMICAL SOC2022

PHz Electronic Device Design and Simulation for Waveguide-Integrated Carrier-Envelope Phase Detection

Yujia Yang

Carrier-envelope phase (CEP) detection of ultrashort optical pulses and low-energy waveform field sampling have recently been demonstrated using direct time-domain methods that exploit optical-field photoemission from plasmonic nanoantennas. These devices ...

IEEE Institute of Electrical and Electronics Engineers2022

Versatile shaping of optical frequency combs and applications

Jianqi Hu

Optical frequency combs are a series of phase-locked and equidistant laser lines in the spectral domain. In the time domain, they correspond to periodic pulse trains by the Fourier relation. The ability to shape optical combs and pulse trains is pivotal to ...

EPFL2021

Spectral self-imaging of optical orbital angular momentum modes

Yin Chen, Camille Sophie Brès, Jianqi Hu, Yujie Chen

The Talbot self-imaging effect is mostly present in the forms of space or time, or in the frequency domain by the Fourier duality. Here, we disclose a new spectral Talbot effect arising in optical orbital angular momentum (OAM) modes. The effect occurs in ...

AIP Publishing2021

Phase calibration of a basic bright-field microscope for 3D metrology of transparent samples at the nanoscale

Martinus Gijs, Daniel Migliozzi, Bingying Zhao

Optical retrieval of the structure of transparent objects at the nano-scale requires adapted methods capable of probing their interaction with suitable light. Scattering events, for instance, depend on the content and the arrangement of the medium encounte ...

SPIE-INT SOC OPTICAL ENGINEERING2021

Polarization-sensitive optics diffraction tomography

Demetri Psaltis, Ahmed Ayoub, Joowon Lim, Elizabeth Elena Antoine, Amirhossein Saba Shirvan

Polarization of light has been widely used as a contrast mechanism in two-dimensional (2D) microscopy and also in some three-dimensional (3D) imaging modalities. In this paper, we report the 3D tomographic reconstruction of the refractive index (RI) tensor ...

2021

QUAREP-LiMi: A community-driven initiative to establish guidelines for quality assessment and reproducibility for instruments and images in light microscopy

Andrea Bassi, Antje Keppler, Arne Seitz

A modern day light microscope has evolved from a tool devoted to making primarily empirical observations to what is now a sophisticated , quantitative device that is an integral part of both physical and life science research. Nowadays, microscopes are fou ...

WILEY2021

Metasurfaces for label-free biosensing mid-infrared optics and active photonic devices

Aleksandrs Leitis

Novel two-dimensional metamaterials, known as metasurfaces, have emerged as a breakthrough platform for controlling electromagnetic wave properties at the nanoscale. These metasurfaces consist of subwavelength nanoantennas or so-called meta-atoms, which ca ...

EPFL2021

Photonic chip-based resonant supercontinuum via pulse-driven Kerr microresonator solitons

Tobias Kippenberg, Tobias Herr, Junqiu Liu, Miles Henry Anderson, Wenle Weng

Supercontinuum generation and soliton microcomb formation both represent key techniques for the formation of coherent, ultrabroad optical frequency combs, enabling the RF-to-optical link. Coherent supercontinuum generation typically relies on ultrashort pu ...

2021

High-Resolution Transmission Electron Microscopy with Bright Microsecond Electron Pulses

Marcel Drabbels, Ulrich Lorenz, Pavel Olshin, Gabriele Bongiovanni

Transmission electron microscopy at atomic-resolution is a crucial tool in a variety of fields, ranging from materials science to biology. [1,2] Fast electron cameras have recently enabled high-speed observations atomic resolution. [3] Moreover, they have ...

2021

Structured light generation by refractive-diffractive micro optical array illuminators

Maryam Yousefi

Structured light generation having broad applications in different optical fields, is the topic of this thesis. Our structured light generation strategy is based on applying periodic microoptical elements at the refraction-diffraction limit, under a focuse ...

EPFL2021

All-Dielectric Programmable Huygens' Metasurfaces

Hatice Altug, Andreas Tittl, Aleksandrs Leitis

Low-loss nanostructured dielectric metasurfaces have emerged as a breakthrough platform for ultrathin optics and cutting-edge photonic applications, including beam shaping, focusing, and holography. However, the static nature of their constituent materials ...

2020