Publications associées à Compensation of visual backward masking deficits in relatives of schizophrenia patients

An immersive virtual reality tool for assessing left and right unilateral spatial neglect

Olaf Blanke, Andrea Serino, Roberta Ronchi

The reported rate of the occurrence of unilateral spatial neglect (USN) is highly variable likely due to the lack of validity and low sensitivity of classical tools used to assess it. Virtual reality (VR) assessments try to overcome these limitations by pr ...

Wiley2024

Molecular reconstruction and simulation of the Neuron-Glia-Vasculature system

Polina Shichkova

The outstanding information processing capacity of the brain relies on numerous molecular mechanisms. It is an extremely energy-expensive function, which involves specialization and collaboration of different cell types. A common framework to study the com ...

EPFL2023

Comparison of Responses to DCN vs. VCN Stimulation in a Mouse Model of the Auditory Brainstem Implant (ABI)

Nicolas Vachicouras, Stéphanie Lacour, Florent-Valéry Coen

The auditory brainstem implant (ABI) is an auditory neuroprosthesis that provides hearing to deaf patients by electrically stimulating the cochlear nucleus (CN) of the brainstem. Whether such stimulation activates one or the other of the CN's two major sub ...

SPRINGER2022

Topology of synaptic connectivity constrains neuronal stimulus representation, predicting two complementary coding strategies

Michael Reimann, Ran Levi, Christoph Pokorny

In motor-related brain regions, movement intention has been successfully decoded from invivo spike train by isolating a lower-dimension manifold that the high-dimensional spiking activity is constrained to. The mechanism enforcing this constraint remains u ...

PUBLIC LIBRARY SCIENCE2022

Timing is Everything

Karen Adam

In this thesis, timing is everything. In the first part, we mean this literally, as we tackle systems that encode information using timing alone. In the second part, we adopt the standard, metaphoric interpretation of this saying and show the importance of ...

EPFL2022

Uncovering the neural encoding of behavior in the adult Drosophila motor system

Chin-Lin Chen

One of the most important goals in neuroscience research has always been to understand how animals control their behavior. However, the long focus on the role of brain neurons in behavioral control might be missing the full story. In fact, brain-wide fluct ...

EPFL2022

The shine-through paradigm and the schizophrenia spectrum: a summary

Michael Herzog, Maya Roinishvili, Ophélie Gladys Favrod, Simona Adele Garobbio, Janir Nuno Ramos Antunes Da Cruz

In the past 10 years, our laboratory has proved the shine-through paradigm to be a very sensitive endophenotype for schizophrenia. The shine-through paradigm is a visual backward masking task, where the target is a vertical vernier followed by a 25-element ...

2021

Clustering and control for adaptation uncovers time-warped spike time patterns in cortical networks in vivo

James Bryden Isbister

How information in the nervous system is encoded by patterns of action potentials (i.e. spikes) remains an open question. Multi-neuron patterns of single spikes are a prime candidate for spike time encoding but their temporal variability requires further c ...

Nature Research2021

Electrophysiological correlates of visual backward masking in patients with bipolar disorder

Michael Herzog, Maya Roinishvili, Ophélie Gladys Favrod, Simona Adele Garobbio, Janir Nuno Ramos Antunes Da Cruz

In visual backward masking (VBM), a target is followed by a mask that decreases target discriminability. Schizophrenia patients (SZ) show strong and reproducible masking impairments, which are associated with reduced EEG amplitudes. Patients with bipolar d ...

2021

Neural Compensation Mechanisms of Siblings of Schizophrenia Patients as Revealed by High-Density EEG

Michael Herzog, Maya Roinishvili, Ophélie Gladys Favrod, Patricia Figueiredo, Albulena Jashari-Shaqiri, Janir Nuno Ramos Antunes Da Cruz

Visual backward masking (VBM) deficits are candidate endophenotypes of schizophrenia indexing genetic liability of the disorder. In VBM, a target is followed by a mask that deteriorates target perception. Schizophrenia patients and, to a lesser extent, the ...

2020

Spatial covariance improves BCI performance for late ERPs components with high temporal variability

Ricardo Andres Chavarriaga Lozano, José del Rocio Millán Ruiz, Marija Uscumlic, Lucian Andrei Gheorghe, Ruslan Aydarkhanov

Objective. Event Related Potentials (ERPs) reflecting cognitive response to external stimuli, are widely used in brain computer interfaces. ERP waveforms are characterized by a series of components of particular latency and amplitude. The classical ERP dec ...

2020

Modeling time-varying brain networks with a self-tuning optimized Kalman filter

Gijs Plomp, David Pascucci

Brain networks are complex dynamical systems in which directed interactions between different areas evolve at the sub-second scale of sensory, cognitive and motor processes. Due to the highly non-stationary nature of neural signals and their unknown noise ...

2020

Psychometrics of Disembodiment and Its Differential Modulation by Visuomotor and Visuotactile Mismatches

Bigna Lenggenhager, Oliver Alan Kannape

Altered states of embodiment are fundamental to the scientific understanding of bodily self consciousness. The feeling of disembodiment during everyday activities is common to clinical conditions; however, the direct study of disembodiment in experimental ...

2020

Towards everyday brain-computer interfacing through decoding visual cognition

Ruslan Aydarkhanov

Decoding visual cognition from non-invasive measurements of brain activity has shown valuable applications. Vision-based Brain-Computer Interfaces (BCI) systems extend from spellers to database search and spatial navigation. Despite the high performance of ...

EPFL2020

Shedding light on excessive crying in babies

Dimitri Nestor Alice Van De Ville, François Lazeyras, Lorena Gonçalves de Alcântara e Freitas Krikler

Background Excessive and inconsolable crying behavior in otherwise healthy infants (a condition called infant colic (IC)) is very distressing to parents, may lead to maternal depression, and in extreme cases, may result in shaken baby syndrome. Despite the ...

NATURE PUBLISHING GROUP2021

Prefrontal High Gamma in ECoG Tags Periodicity of Musical Rhythms in Perception and Imagination

Steffen Alexander Herff

Rhythmic auditory stimuli are known to elicit matching activity patterns in neural populations. Furthermore, recent research has established the particular importance of high-gamma brain activity in auditory processing by showing its involvement in auditor ...

2020

Breathing is coupled with voluntary action and the cortical readiness potential

Olaf Blanke, Oliver Alan Kannape, Coline Barnoud, Hyeongdong Park, Henri Dan Trang

Voluntary action is a fundamental element of self-consciousness. The readiness potential (RP), a slow drift of neural activity preceding self-initiated movement, has been suggested to reflect neural processes underlying the preparation of voluntary action; ...

Nature Research2020

Metabolic and hemodynamic changes in the activated human brain and cerebellar organisation measured by MRS/MRl at 7 Tesla

Yohan Boillat

Although less often investigated than the positive blood-oxygen-level-dependent (BOLD) signal, a negative BOLD signal has also been observed under certain conditions, which could have a neuronal origin. To further investigate the negative BOLD signal from ...

EPFL2020

P300 in the park: feasibility of online data acquisition and integration in a Mobile Brain/Body Imaging setting

Silvestro Micera, Fiorenzo Artoni, Elena Galeasso

In the last years Mobile Brain/Body Imaging (MoBI) has been increasingly used to study cognition in the real world to give more ecological validity to brain imaging studies currently carried out only inside the lab. To increase portability of the setup and ...

IEEE2019

Neural dynamics of the competition between grouping organizations

Michael Herzog, Ophélie Gladys Favrod, Einat Rashal

Neural dynamics of the competition between grouping organizations have been studied to a limited extent. The paradigms used so far confounded grouping operations with task demands, using explicit reports of the predominantly perceived organization and bias ...

SAGE PUBLICATIONS LTD2019