Publications associées à Total Synthesis of (±)-Strictamine

CO2 Capture and Release in Amine Solutions: To What Extent Can Molecular Simulations Help Understand the Trends?

Wanda Andreoni, Fabio Pietrucci, Changru Ma

Absorption in amine solutions is a well-established advanced technology for CO2 capture. However, the fundamental aspects of the chemical reactions occurring in solution still appear to be unclear. Our previous investigation of aqueous monoethanolamine (ME ...

2023

Low-tech methods for the reuse of reinforced concrete structural elements

Maléna Bastien Masse, Julie Rachel Devènes, Corentin Jean Dominique Fivet, Nicole Widmer

Most of existing buildings are made of concrete, new buildings are being built with it and others are demolished when still in good structural condition. This drives increased demands for raw materials, greenhouse gas emissions, and an accumulation of demo ...

2023

A Collaborative Workflow to Automate the Design, Analysis, and Construction of Integrally-Attached Timber Plate Structures

Pierre Latteur, Yves Weinand, Aryan Rezaei Rad, Petras Vestartas, Nicolas Henry Pierre Louis Rogeau

This paper introduces a computational framework that fosters collaboration between architects, engineers, and contractors by bridging the gap between architectural design, structural analysis, and digital construction. The present research is oriented towa ...

CAADRIA2022

Reactions of amines with ozone and chlorine: Two novel oxidative methods to evaluate the N-DBP formation potential from dissolved organic nitrogen

Karim-Alexandre Essaied, Urs von Gunten, Lucy Victoria Brown

The composition of oxidant-reactive dissolved organic nitrogen (DON) is poorly characterized, although its ozonation is likely to form a great variety of disinfection by-products containing a nitrogen-oxygen bond (NDBPs). In this study, two chemical oxidat ...

PERGAMON-ELSEVIER SCIENCE LTD2022

Enhanced Treatment of Municipal Wastewater Effluents by Fe-TAML/H2O2: Efficiency of Micropollutant Abatement

Urs von Gunten

Combining iron with a tetraamido-macrocyclic ligand (Fe-TAML) as a catalyst and with hydrogen peroxide (H2O2) as the bulk oxidant is a process that has been suggested for the oxidative abatement of micropollutants during water treatment. In this study, the ...

AMER CHEMICAL SOC2021

New Vinylation and Alkynylation Strategies with Hypervalent Iodine Reagents and Diazo Compounds

Guillaume Dominique Pisella

The development of a sequential copper-catalyzed oxy-alkynylation/intramolecular [4+2] cycloaddition of allenes and arenes was investigated at first. This one-pot protocol allowed the construction of complex polycylic architectures with high efficiency fro ...

EPFL2021

Reactions of nitrogen-containing compounds with ozone: kinetics and mechanisms

Sung Eun Lim

Nitrogen-containing moieties are widespread in natural waters in dissolved organic nitrogen and micropollu-tants. They are often susceptible to an electrophilic attack of ozone because of the electron-rich nature of the neutral form of nitrogen in organic ...

EPFL2020

Development of Novel Standardized Structural Timber Elements Using Wood-Wood Connections

Julien Gamerro

Traditional wood-wood connections, widely used in the past, have been progressively replaced by steel fasteners and bonding processes in modern timber constructions. However, the emergence of digital fabrication and innovative engineered timber products ha ...

EPFL2020

Organocatalysts in C-N Bond Forming Reactions of Amines with CO2

Martin Hulla

The thesis describes a simple approach for N-formylation of amines with CO2 and hydrosilane reducing agents, the use of organic salts as N-formylation catalysts, their physical properties required for high catalytic activity and their role in the catalytic ...

EPFL2019

Delineation of the Critical Parameters of Salt Catalysts in the N-Formylation of Amines with CO2

Paul Joseph Dyson, Daniel Ortiz Trujillo, Dmitry Vasilyev, Martin Hulla

N-formylation of amines with CO2 is base-catalyzed and studies of salt catalysts reveal that the reaction is efficiently catalyzed by "free" floating anions of high basicity, as represented in the cover image. More information can be found in the Full Pape ...

WILEY-V C H VERLAG GMBH2019

Photoredox-Catalyzed Decarboxylation for the Transfer of Alkynes and Nitriles Using Hypervalent Iodine Reagents

Franck Le Vaillant

Aliphatic alkynes and nitriles are privileged motifs in organic chemistry. Therefore, alkynes and nitriles have played a central role for the exploration and development of novel strategies to forge C-C bonds in efficient manner. They are broadly used as v ...

EPFL2019

Design of Truss Structures Through Reuse

Joseph Jean François Desruelle, Corentin Jean Dominique Fivet, Jan Friedrich Georg Brütting, Gennaro Senatore

This paper presents structural optimization techniques to design truss structures that make best use of a given stock of structural components. Still little explored, the reuse of structural components over multiple service lives has the potential to signi ...

2019

Designing Energy-Efficient Façades to Meet Energy Transition Targets

Angela Clua Longas

The contemporary energy context can be considered as a period of energy transition, where the latest protocols focus on limiting greenhouse gas (GHG) emissions and improving energy efficiency across the different energy consumption sectors. As the largest ...

EPFL2019

Shape and size control of colloidal CdSe nanocrystals in the presence of carboxylate and alkylamine ligands

Xiaopeng Huang

In this thesis, we focus on investigating the shape and size evolution of colloidal CdSe nanomaterials in the presence of carboxylate and alkylamine surface ligands. By elaborating the combination of carboxylates and alkylamines with different hydrocarbon ...

EPFL2019

Mechanistic Study of the N-Formylation of Amines with Carbon Dioxide and Hydrosilanes

Gabor Laurenczy, Paul Joseph Dyson, Martin Hulla

N-formylation of amines with CO2 and hydrosilane reducing agents proceeds via fast and complex chemical equilibria, which hinder easy analysis of the reaction pathways. In situ reaction monitoring and kinetic studies reveal that three proposed pathways, vi ...

2018

Re-assessing the Formation of N-nitrosamines during Chloramination of Various Nitrogenous Compounds using Specific and Total N-nitrosamines Analysis

Florian Frédéric Vincent Breider, Urs von Gunten, Andrea Piazzoli

N-nitrosamines (NOAs) are potent carcinogenic and mutagenic compounds that can be present in water, biological fluids, food, consumer products and cigarette smoke. Several studies have shown that the formation of NOAs in water can arise from the reactions ...

2018

Applying a Trojan Horse Strategy to Ruthenium Complexes in the Pursuit of Novel Antibacterial Agents

Paul Joseph Dyson, Lucinda Kate Batchelor, Quentin François Antoine Laurent

Siderophores are iron chelators secreted by bacteria to scavenge iron(III) from their surrounding environment. They possess their own internalization pathway that is sufficiently unselective to be hijacked, making them suitable for Trojan Horse strategy ap ...

2018

Cross-Coupling of Alkyl Redox-Active Esters with Benzophenone Imines: Tandem Photoredox and Copper Catalysis

Xile Hu, Jonathan Balon, Runze Mao

Alkyl amines are an important class of organic compounds in medicinal and materials chemistry. Until now very have been very few methods for the synthesis of alkyl amines by metal‐catalyzed cross‐coupling of alkyl electrophiles with nitrogen nucleophiles. ...

Wiley-VCH Verlag GmbH2018

Smart Living Building Research Program - Executive Summary

Vanda Carla Costa Grisel, Emmanuel Rey, Marilyne Andersen, Cédric Liardet, Thomas Bernard Paul Jusselme, Arianna Brambilla, Endrit Hoxha, Stefano Cozza, Amélie Zizou Gisèle Renée Poncety, Didier Albert Simon Vuarnoz

The smart living lab project is a pioneering, inter-disciplinary and inter-institutional platform that combines several fields of research related to construction technologies. It aims to be a center of national scope, recognized on an international level ...

2017

Functional and Adaptive Construction for Rescue : an Analysis of the Approach Using Autonomous Robots

Hadi Ardiny

Although recent advances in the field of robotics have greatly increased robotic capabilities for several applications, autonomous robots are still in their infancy regarding their support of onsite construction. Unlike production robots that are used, for ...

EPFL2017