Publications associées à Developing a method to derive alcohol-attributable fractions for HIV/AIDS mortality based on alcohol's impact on adherence to antiretroviral medication

Artificial intelligence of things for smart cities: advanced solutions for enhancing transportation safety

In the context of smart cities, ensuring road safety is crucial due to increasing urbanization and the interconnected nature of contemporary urban environments. Leveraging innovative technologies is essential to mitigate risks and create safer communities. ...

Springernature2024

Medical and Personal Characteristics Can Predict the Risk of Lung Metastasis

Michele De Palma, Nahal Mansouri

Aims: Understanding the correlations between underlying medical and personal characteristics of a patient with cancer and the risk of lung metastasis may improve clinical management and outcomes. We used machine learning methodologies to predict the risk o ...

2023

Associations between urinary biomarkers of oxidative stress and biomarkers of tobacco smoke exposure in smokers

Dominique Grandjean, Florian Frédéric Vincent Breider, Nicolas Sambiagio

Oxidative stress can contribute to the development of diseases, and may originate from exposures to toxicants commonly found in air pollution and cigarette smoke such as polycyclic aromatic hydrocarbons (PAHs) and volatile organic compounds (VOCs). Yet, as ...

Elsevier2022

Impaired cognitive flexibility and heightened urgency are associated with increased alcohol consumption in rodent models of excessive drinking

Emanuela De Falco

Alcohol use disorder (AUD) is characterized by impairments in decision-making that can exist as stable traits or transient states. Cognitive inflexibility reflects an inability to update information that guides decision-making and is thought to contribute ...

WILEY2021

Development of remote C-H bond functionalization of redox-active alcohol derivatives and oxidative transformations under photoredox catalysis

Alexandre Julien Florent Leclair

The development of radical-based remote C(sp3)-H functionalizations of redox-active alcohol derivatives, oxidative cycloaddition and rearrangement transformations under visible light photocatalysis constitute the basis of this thesis. The first chapter des ...

EPFL2021

Ten seconds of my nights: Exploring methods to measure brightness, loudness and attendance and their associations with alcohol use from video clips

Daniel Gatica-Perez, Skanda Muralidhar, Lakmal Buddika Meegahapola

Introduction Most evidence on associations between alcohol use behaviors and the characteristics of its social and physical context is based on self-reports from study participants and, thus, only account for their subjective impressions of the situation. ...

2021

Learning Urban Nightlife Routines from Mobile Data

Daniel Gatica-Perez, Thanh Trung Phan

The use of smartphone sensing for public health studies is appealing to understand routines. We present an approach to learn nightlife routines in a smartphone sensing dataset volunteered by 184 young people (1586 weekend nights with location data captured ...

ACM2020

Understanding Eating And Drinking In Context From Crowdsourced Data

Thanh Trung Phan

With the increasing rate of urbanization, understanding food and beverage consumption, including alcohol drinking behaviour with its consequences, is relevant in such a megacity in the future. Especially, investigation of alcohol drinking is necessary for ...

EPFL2020

Youth nightlife at home: towards a feminist conceptualisation of home

Daniel Gatica-Perez, Darshan Santani

This paper explores home as a space of youth nightlife and drinking through a feminist lens. It draws on feminist geographical scholarship on home and 40 semi-structured interviews with young people aged 16–25 in Switzerland in the context of a larger inte ...

2021

Understanding Heavy Drinking at Night through Smartphone Sensing and Active Human Engagement

Daniel Gatica-Perez, Skanda Muralidhar, Thanh Trung Phan

Heavy alcohol consumption can lead to many severe consequences. In this paper, we study the phenomenon of heavy drinking at night (4+ drinks for women or 5+ for men on a single evening), using a smartphone sensing dataset depicting about nightlife and drin ...

ACM2020

Shooting shots: Estimating alcoholic drink sizes in real life using event-level reports and annotations of close-up pictures

Daniel Gatica-Perez, Thanh Trung Phan

Introduction and Aims Drinks consumed in real life are diverse, in terms of beverage type, container size and alcohol by volume. To date, most ecological momentary assessment studies have assessed drinking amounts with 'standard' drinks, although their eve ...

WILEY2021

Towards Win-Win Policies for Healthy and Sustainable Diets in Switzerland

Suren Erkman, Arnaud Dauriat

The first Swiss national dietary survey (MenuCH) was used to screen disease burdens and greenhouse gas emissions (GHG) of Swiss diets (vegan, vegetarian, gluten-free, slimming), with a focus on gender and education level. The Health Nutritional Index (HENI ...

MDPI2020

The contexts of heavy drinking: A systematic review of the combinations of context-related factors associated with heavy drinking occasions

Background The amount of alcohol consumed during an occasion can be influenced by physical and social attributes of the setting, characteristics and state of individuals, and the interactions of these components. This systematic review identifies and descr ...

2019

After how many drinks does someone experience acute consequences-determining thresholds for binge drinking based on two event-level studies: Optimal thresholds for binge drinking

Background and Aims: The threshold of 4+/5+ drinks per occasion has been used for decades in alcohol research to distinguish between non risky versus risky episodic drinking. However, no study has assessed the validity of this threshold using event level d ...

2018

DrinkSense: Characterizing Youth Drinking Behavior using Smartphones

Daniel Gatica-Perez, Darshan Santani

Alcohol consumption is the number one risk factor for morbidity and mortality among young people. In late adolescence and early adulthood, excessive drinking and intoxication are more common than in any other life period, increasing the risk of adverse phy ...

2018

What Reminds Young People That They Drank More Than Intended on Weekend Nights: An Event-Level Study

Objective: Young people often drink more alcohol than intended over the course of a night. This study investigates individual and night-specific factors predicting young people’s acknowledgment of having drunk more than intended. Method: Using the Youth@Ni ...

2018

A preclinical model for identifying rats at risk of alcohol use disorder

Pierre Magistretti, Benjamin Boutrel

Alcohol use is one of the world's leading causes of death and disease, although only a small proportion of individuals develop persistent alcohol use disorder (AUD). The identification of vulnerable individuals prior to their chronic intoxication remains o ...

Springer Nature2017

PARP inhibition protects against alcoholic and non-alcoholic steatohepatitis

Johan Auwerx, Zhou Zhou, Dongryeol Ryu, Karim Laurent Gariani, Wei Wang

Background & Aims: Mitochondria) dysfunction, oxidative stress, inflammation, and metabolic reprograming are crucial contributors to hepatic injury and subsequent liver fibrosis. Poly(ADP-ribose) polymerases (PARP) and their interactions with sirtuins play ...

Elsevier Science Bv2017

Thermally-nucleated self-assembly of water and alcohol into stable structures at hydrophobic interfaces

Francesco Stellacci, Kislon Voitchovsky, Michele Ceriotti, Daniele Giofré

At the interface with solids, the mobility of liquid molecules tends to be reduced compared with bulk, often resulting in increased local order due to interactions with the surface of the solid. At room temperature, liquids such as water and methanol can f ...

Nature Publishing Group2016

Hydrophobic hydration of poly-N-isopropyl acrylamide: a matter of the mean energetic state of water

Paolo De Los Rios

The enthalpically favoured hydration of hydrophobic entities, termed hydrophobic hydration, impacts the phase behaviour of numerous amphiphiles in water. Here, we show experimental evidence that hydrophobic hydration is strongly determined by the mean ener ...

Nature Publishing Group2014