Publications associées à Ophthalmic system and method for clinical device using transcleral illumination with multiple points source

In Vivo Retinal Pigment Epithelium Imaging using Transscleral Optical Imaging in Healthy Eyes

Christophe Moser, Mathieu Künzi, Timothé Laforest, Laura Emmanuelle Kowalczuk

Objective: To image healthy retinal pigment epithelial (RPE) cells in vivo using Transscleral OPtical Imaging (TOPI) and to analyze statistics of RPE cell features as a function of age, axial length (AL), and eccentricity. Design: Single-center, explorator ...

ELSEVIER2022

Multi-modal retinal imaging platform

Christophe Moser, Mathieu Künzi, Timothé Laforest

The invention relates to oblique transscleral illumination of an eye fundus with at least one physical point light source around the eye allowing for dark field imaging combined with optical coherence tomography imaging. ...

2021

Homogeneous light stimulation of melanopsin and cones with a Maxwellian view device for the human eye

Gilles Evéquoz, Patrick Robert Flückiger

We designed and tested a device to stimulate specifically one photoreceptor type, or a combination of some of them, of the human eye by using up to six primaries. The device produces a homogeneous light field over 40 degrees which is projected onto the ret ...

IEEE2021

OCT-angiography assessing quiescent and active choroidal neovascularization in retinitis pigmentosa associated with PRPH2 pathogenic variant

Imen Habibi

Purpose: To report multimodal imaging findings including optical coherence tomography angiography (OCT-A) of a patient presenting with a quiescent choroidal neovascularization (CNV) in one eye and an active CNV in the fellow eye, complicating retinitis pig ...

2021

Optical phase contrast imaging of human retinal cells by changing the tissue refractive index

Christophe Moser, Mathieu Künzi, Timothé Laforest, Laura Emmanuelle Kowalczuk

Purpose : Based on oblique partially coherent illumination of transparent samples, we developed a simple custom Optical Phase Imaging (OPI) microscope providing a label-free, semi-quantitative phase contrast imaging. The aim of this study was to explore th ...

ASSOC RESEARCH VISION OPHTHALMOLOGY INC2020

MRI-based brain volumetry and retinal optical coherence tomography as the biomarkers of outcome in acute methanol poisoning

Bénédicte Marie Maréchal, Tobias Kober

Background: Basal ganglia lesions are typical findings on magnetic resonance imaging (MRI) of the brain in survivors of acute methanol poisoning. However, no data are available on the association between the magnitude of damaged brain regions, serum concen ...

ELSEVIER2020

Outcome and Complications of Combined Modified Deep Sclerectomy and Trabeculectomy for Surgical Management of Glaucoma: A Pilot Study

André Mermoud, Sylvain Roy

Purpose: To report the outcome and complications of a combined surgical technique of modified deep sclerectomy and trabeculectomy (mDST) for glaucoma. Patients and Methods: Retrospective study of 44 eyes of 43 patients with open and closed angle glaucoma w ...

2020

3-Dimensional magnetic resonance imaging of the freely moving human eye

Jérôme Yerly, Silvio Ionta, Josefina Adriana Maria Bastiaansen, David Zeugin, João Pedro Forjaco Jorge, Benedetta Franceschiello, Lorenzo Di Sopra

Eye motion is a major confound for magnetic resonance imaging (MRI) in neuroscience or ophthalmology. Currently, solutions toward eye stabilisation include participants fixating or administration of paralytics/anaesthetics. We developed a novel MRI protoco ...

PERGAMON-ELSEVIER SCIENCE LTD2020

Image reconstruction for novel time domain near infrared optical tomography: towards clinical applications

Edoardo Charbon, Scott Anthony Lindner, Jingjing Jiang, Chunmin Zhang, Martin Wolf

Near infrared optical tomography (NIROT) is an emerging modality that enables imaging the oxygenation of tissue, which is a biomarker of tremendous clinical relevance. Measuring in reflectance is usually required when NIROT is applied in clinical scenarios ...

2020

Solution-Processed Organic Optical Upconversion Device

Frank Nüesch, Roland Hany, Santhanu Panikar Ramanandan, Sina Abdolhosseinzadeh, Matthias Diethelm

Imaging in the near-infrared (NIR) is getting increasingly important for applications such as machine vision or medical imaging. NIR-to-visible optical upconverters consist of a monolithic stack of a NIR photodetector and a visible light-emitting unit. Suc ...

AMER CHEMICAL SOC2019

Near-infrared absorbing cyanine dyes for all-organic optical upconversion devices

Frank Nüesch, Roland Hany, Matthias Diethelm

The development of near-infrared (NIR) photodetection technologies is driven by emerging applications such as medical imaging or optical sensors for electronic displays and machine vision. An all-organic upconverter (OUD) is a device that converts incident ...

2019

En face retinal imaging

Dino Carpentras

Retinal imaging is routinely used to provide information about vision health. Recent studies showed that retinal images can also provide information on general health (e.g. stress level), brain pathologies and attention. Depending on the target information ...

EPFL2018

System, method and apparatus for retinal absorption phase and dark field imaging with oblique illumination

Christophe Moser, Mathieu Künzi, Dino Carpentras, Timothé Laforest

A method for imaging a tissue of an eye, the method including the steps of providing oblique illumination to the eye by a plurality of light emitting areas of a light delivery device, the plurality of light emitting areas being independently controllable a ...

2017

Reduced metabolic function and structural alterations in inherited retinal dystrophies: investigating the effect of peripapillary vessel oxygen saturation and vascular diameter on the retinal nerve fibre layer thickness

PurposeTo evaluate the relationship between the peripapillary metabolic alterations [retinal vessel Oximetry (RO)] and the structural findings [retinal vessel diameter and retinal nerve fibre layer thickness (RNFL)] in patients with inherited retinal dystr ...

Wiley2017

See-through ophthalmoscope for retinal imaging

Christophe Moser, Dino Carpentras

With the miniaturization of scanning mirrors and the emergence of wearable health monitoring, an intriguing step is to investigate the potential of a laser scanning ophthalmoscope (LSO) for retinal imaging with wearable glasses. In addition to providing mo ...

SPIE Society of Photo-optical Instrumentation Engineers2017

Compact Side and Multi Angle Illumination Lensless Imager and Method of Operating the Same

Christophe Moser, Manon Rostykus

A system for subpixel resolution imaging of an amplitude and quantitative phase image, the system including a waveguide having a top plane, a bottom plane, and two sides, an array of light sources emitting first befit beams from one side of the two sides o ...

2017

Potential blindness in children of patients with hereditary bone disease

Mono- and bi-allelic mutations in the low-density lipoprotein receptor related protein 5 (LRP5) may cause osteopetrosis, autosomal dominant and recessive exudative vitreoretinopathy, juvenile osteoporosis, or persistent hyperplastic primary vitreous (PHPV) ...

Springer London Ltd2016

Landmark Detection for Fusion of Fundus and MRI Toward a Patient-Specific Multimodal Eye Model

Meritxell Bach Cuadra, Carlos Ciller

Ophthalmologists typically acquire different image modalities to diagnose eye pathologies. They comprise, e.g., Fundus photography, optical coherence tomography, computed tomography, and magnetic resonance imaging (MRI). Yet, these images are often complem ...

Ieee-Inst Electrical Electronics Engineers Inc2015

Novel ADAM9 homozygous mutation in a consanguineous Egyptian family with severe cone-rod dystrophy and cataract

Tatiana Favez

Objective To genetically and phenotypically describe a new ADAM9 homozygous mutation in a consanguineous family from Egypt with autosomal recessive cone-rod dystrophy (arCRD), anterior polar and posterior subcapsular cataract. Design, setting and participa ...

Bmj Publishing Group2014

Retinal vessel oxygen saturation and its correlation with structural changes in retinitis pigmentosa

Purpose: To study the influence of retinal structural changes on oxygen saturation in retinitis pigmentosa (RP) patients. Methods: Oximetry measurements were performed on 21 eyes of 11 RP patients and compared to 24 eyes of 12 controls. Retinal oxygen satu ...

Wiley-Blackwell2014