Publication

Principles of operation of a DNP prepolarizer coupled to a rodent MRI scanner

Publications associées (13)

An optimized protocol for assessing changes in mouse whole-brain activity using opto-fMRI

Functional magnetic resonance imaging (fMRI) in mouse brain, paired with spatially and temporally defined manipulations, offers a powerful tool to causally explain the effect of specific neuronal activity on brain network dynamics. Here, we present an opti ...

ELSEVIER2022

Brainstem Correlates of a Cold Pressor Test Measured by Ultra-High Field fMRI

Dimitri Nestor Alice Van De Ville, Fatma Megdiche, Olivier Benoit Thomas Reynaud, Domenica Bueti

Introduction Modern imaging techniques such as blood oxygen level-dependent (BOLD) functional magnetic resonance imaging (fMRI) allow the non-invasive and indirect measurement of brain activity. Whether changes in signal intensity can be detected in small ...

2020

Multi-slice passband bSSFP for human and rodent fMRI at ultra-high field

Rolf Gruetter, Rodrigo Araujo Fraga Da Silva, Olivier Benoit Thomas Reynaud, Ileana Ozana Jelescu

Balanced steady-state free precession (bSSFP) can be used as an alternative to gradient-echo (GE) EPI for BOLD functional MRI when image distortions and signal drop-outs are severe such as at ultra-high field. However, 3D-bSSFP acquisitions have distinct d ...

Academic Press Inc - Elsevier Science2019

Fast model-based T-2 mapping using SAR-reduced simultaneous multislice excitation

Jean-Philippe Thiran, Gunnar Krüger, Tobias Kober, José Pedro Rebelo Ferreira Marques, Tom Hilbert

Purpose To obtain whole-brain high-resolution T-2 maps in 2 minutes by combining simultaneous multislice excitation and low-power PINS (power independent of number of slices) refocusing pulses with undersampling and a model-based reconstruction. Methods A ...

WILEY2019

Study of cortical energy metabolism during sensory stimulation-induced brain activity by ¹³C magnetic resonance spectroscopy in vivo

Sarah Catherine Sonnay

Cerebral function is associated with high metabolic activity that is supported by continuous supply of oxygen and glucose from the blood. Coupling between brain energy metabolism and neuronal activity has been studied extensively during the past decades. N ...

EPFL2017

Ultra-High Field Birdcage Coils: a Comparison Study at 14.1T

Arnaud Comment, Rolf Gruetter, Hongxia Lei, Tian Cheng

An essential feature of magnetic resonance (MR) probes for magnetic resonance imaging and spectroscopy is the ability to generate uniform B-1(+) excitation in a volume of interest. When the magnetic field strength is increased, leading to an increase in re ...

Ieee2014

A 7 tesla FMRI study of amygdala responses to fearful faces

Nouchine Hadjikhani, Wietske Van der Zwaag, Nicole Regula Zürcher Wimmer

The amygdalae are involved in the perception of emotions such as happiness, anger and fear. Because of their proximity to the sinuses, the image signal intensity in T2* weighted fMRI data is often affected by signal loss due to through-slice dephasing, esp ...

2012

High Time-Resolved Cardiac Functional Imaging Using Temporal Regularization for Small Animal on a Clinical 3T Scanner

Dimitri Nestor Alice Van De Ville, Jean-Noël Hyacinthe

Accurate assessment of mice cardiac function with magnetic resonance imaging is essential for longitudinal studies and for drug development related to cardiovascular diseases. Whereas dedicated small animal MR scanners are not readily available, it would b ...

2012

Spread spectrum magnetic resonance imaging

Jean-Philippe Thiran, Pierre Vandergheynst, Dimitri Nestor Alice Van De Ville, Rolf Gruetter, Yves Wiaux, José Pedro Rebelo Ferreira Marques, Gilles Puy

We propose a novel compressed sensing technique to accelerate the magnetic resonance imaging (MRI) acquisition process. The method, coined spread spectrum MRI or simply s2MRI, consists of pre-modulating the signal of interest by a linear chirp before rando ...

Institute of Electrical and Electronics Engineers2012

Toward Reliable MR-Based Brain Structure Morphometry : Importance of Rigorous Quality Control

Bénédicte Marie Maréchal

Dementing neurodegenerative disorders have more and more prominent public health implications with the most frequent cause being the currently non reversible Alzheimer's Disease (AD). However, over the past 15 years, an abundant literature has demonstrated ...

EPFL2011

Hybrid Small Animal Imaging System Combining Magnetic Resonance Imaging with Fluorescence Tomography Using Single Photon Avalanche Diode Detectors

Edoardo Charbon, Lucio Carrara, Christof Baltes, Markus Rudin

The high sensitivity of fluorescence imaging enables the detection of molecular processes in living organisms. However, diffuse light propagation in tissue prevents accurate recovery of tomographic information on fluorophore distribution for structures emb ...

Institute of Electrical and Electronics Engineers2011

Design and performance of a DNP prepolarizer coupled to a rodent MRI scanner

Arnaud Comment, Jacques Van Der Klink, Rolf Gruetter, Sami Jannin, Fiodar Kurdzesau

For most of the last forty years, the techniques of Dynamic Nuclear Polarization (DNP) have been confined to particle-physics laboratories building polarized targets, but recently it has been shown that samples similar to a solid target can be transformed ...

2007

Spatio-temporal coupling of the electric and hemodynamic brain responses in humans

Roberto Martuzzi

Our comprehension of human brain functions and their dynamics has been dramatically improved by recent developments in non-invasive imaging techniques. These methods can be divided into two different categories, according to the nature of the measured sign ...

EPFL2006